EVALUATION OF SERUM TROPONIN T MEASUREMENTIN ACUTE MYOCARDIAL INFARCTION

EVALUATION OF SERUM TROPONIN T MEASUREMENTIN ACUTE MYOCARDIAL INFARCTION

The release kinetics of the cardiac specific troponin T (cTnT), measured by an immunosorbent assay, in 32 patients with acute myocardial infarction (AMI) was evaluated. In 8 AMI patients (25%), the release kinetics of serum cTnT showed biphasic serum concentration curves with a large peak at 10 to 1...

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Veröffentlicht in:中华医学杂志：英文版 1995 (7), p.23-27
1. Verfasser: 于宏伟 赵文娟 范洪亮 徐庆科 苗志敏
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刀口
回回
回气
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container_title 中华医学杂志：英文版
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creator 于宏伟 赵文娟 范洪亮 徐庆科 苗志敏
description The release kinetics of the cardiac specific troponin T (cTnT), measured by an immunosorbent assay, in 32 patients with acute myocardial infarction (AMI) was evaluated. In 8 AMI patients (25%), the release kinetics of serum cTnT showed biphasic serum concentration curves with a large peak at 10 to 18 hours after onset and the serum cTnT concentrations were up to 30 to 120 times of the normal upper limit-detected (0.2 μg / ml), and another samll cTnT peak at 70 to 100 hours after onset of pain. The serum cTnT measurements in the remaining 24 AMI patients (75%) gave only one large peak which was around 32 to 108 hours after onset of pain. cTnT appeared in serum as early as 3 to 4 hours and remained elevated until 240 hours after the infarctions. The results indicated that (1) cTnT was a sensitive and specific marker of AMI; (2) the biphasic curve of cTnT releae in general, the ratio of cTnT at around 14 to 32 (14/32)>1 in particular, may be a useful marker suggesting early reperfusion; (3) the continuous
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The results indicated that (1) cTnT was a sensitive and specific marker of AMI; (2) the biphasic curve of cTnT releae in general, the ratio of cTnT at around 14 to 32 (14/32)&amp;gt;1 in particular, may be a useful marker suggesting early reperfusion; (3) the continuous</description><identifier>ISSN: 0366-6999</identifier><identifier>EISSN: 2542-5641</identifier><language>eng</language><subject>刀口 ; 回回 ; 回气</subject><ispartof>中华医学杂志：英文版, 1995 (7), p.23-27</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttp://image.cqvip.com/vip1000/qk/85656X/85656X.jpg</thumbnail><link.rule.ids>314,780,784,4022</link.rule.ids></links><search><creatorcontrib>于宏伟 赵文娟 范洪亮 徐庆科 苗志敏</creatorcontrib><title>EVALUATION OF SERUM TROPONIN T MEASUREMENTIN ACUTE MYOCARDIAL INFARCTION</title><title>中华医学杂志：英文版</title><addtitle>Chinese Medical Journal</addtitle><description>The release kinetics of the cardiac specific troponin T (cTnT), measured by an immunosorbent assay, in 32 patients with acute myocardial infarction (AMI) was evaluated. 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subjects 刀口
回回
回气
title EVALUATION OF SERUM TROPONIN T MEASUREMENTIN ACUTE MYOCARDIAL INFARCTION
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