A New Efficient Synthetic Method for 3-1odothyronamine and Its Potent Hypothermic Efficacy

A New Efficient Synthetic Method for 3-1odothyronamine and Its Potent Hypothermic Efficacy

We developed a new efficient synthetic method for a 3-iodothyronamine （TjAM） that has advantages of less synthetic steps and much higher overall yield compared to those in the conventional method. Our animal study showed that TTAM synthesized by the method exerted a potent hypothermic effect in non-...

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Veröffentlicht in:中国化学：英文版 2011, Vol.29 (10), p.2205-2208
1. Verfasser: Kim, Joong-Gon Song, Young-Kyu Jeon, Su-Yeon Lim, Ye-Ji Ju, Hyunwo Choi, Inho Chung, Chan-Moon
Format: Artikel
Sprache:eng
Schlagworte:
低温
功效
动物实验
合成方法
收益率
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Zusammenfassung:We developed a new efficient synthetic method for a 3-iodothyronamine （TjAM） that has advantages of less synthetic steps and much higher overall yield compared to those in the conventional method. Our animal study showed that TTAM synthesized by the method exerted a potent hypothermic effect in non-hibernator mice.
ISSN:1001-604X
1614-7065