PRELIMINARY CRYSTALLOGRAPHIC STUDY OF THE PLATELET AGGREGATION INHIBITOR FROM THE VENOM OF Agkistrodon halys Pallas

PRELIMINARY CRYSTALLOGRAPHIC STUDY OF THE PLATELET AGGREGATION INHIBITOR FROM THE VENOM OF Agkistrodon halys Pallas

In addition to esterasic activity, phospholipase A2 （PLA2） from snake venom possesses various physiological activities and toxicities, such as hemolysis, anticoagulation, platelet function, presynaptic toxicity, muscular toxicity. It has been found that the venom from Agkistrodon halys Pallas has th...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:中国科学通报：英文版 1992 (16), p.1394-1396
1. Verfasser: 桂璐璐 牛秀田 毕汝昌 林政炯 陈远聪
Format: Artikel
Sprache:eng
Schlagworte:
aggregation
crystal
inhibitor
phospholipase
platelet
protein
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 1396
container_issue 16
container_start_page 1394
container_title 中国科学通报：英文版
container_volume
creator 桂璐璐 牛秀田 毕汝昌 林政炯 陈远聪
description In addition to esterasic activity, phospholipase A2 （PLA2） from snake venom possesses various physiological activities and toxicities, such as hemolysis, anticoagulation, platelet function, presynaptic toxicity, muscular toxicity. It has been found that the venom from Agkistrodon halys Pallas has three homologous PLA2, which are quite different from each other in enzymatic activity, presynaptic toxicity, platelet function, hemolysis and anticoagulation. For example, the neutral PLA2 has strong presynaptic toxicity, but no platelet function. On the contrary, the acidic PLA2 can inhibit the platelet aggregation, but
format Article
fullrecord <record><control><sourceid>chongqing</sourceid><recordid>TN_cdi_chongqing_primary_1005156770</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><cqvip_id>1005156770</cqvip_id><sourcerecordid>1005156770</sourcerecordid><originalsourceid>FETCH-chongqing_primary_10051567703</originalsourceid><addsrcrecordid>eNqNi08LgjAcQHcoKMrv8IPOwbRMPC6bOphO1go8xeiPWabluvjtk-gDdHrv8N4AjR3su3Pf8RYjZBlzwxjbS99ZYm-MTCYpZwlLicwhkPlWEc5FJEkWswC2arfJQYSgYgoZJ4pyqoBEkaQRUUykwNKYrZkSEkIpkm-3p2lv_USKe2nebXNqarjqqjOQ6arSZoqGF12Zs_XjBM1CqoJ4frw2dfEq6-LwbMuHbruDjbFruyvPw4v_qg9200MY</addsrcrecordid><sourcetype>Publisher</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>PRELIMINARY CRYSTALLOGRAPHIC STUDY OF THE PLATELET AGGREGATION INHIBITOR FROM THE VENOM OF Agkistrodon halys Pallas</title><source>Alma/SFX Local Collection</source><creator>桂璐璐 牛秀田 毕汝昌 林政炯 陈远聪</creator><creatorcontrib>桂璐璐 牛秀田 毕汝昌 林政炯 陈远聪</creatorcontrib><description>In addition to esterasic activity, phospholipase A2 （PLA2） from snake venom possesses various physiological activities and toxicities, such as hemolysis, anticoagulation, platelet function, presynaptic toxicity, muscular toxicity. It has been found that the venom from Agkistrodon halys Pallas has three homologous PLA2, which are quite different from each other in enzymatic activity, presynaptic toxicity, platelet function, hemolysis and anticoagulation. For example, the neutral PLA2 has strong presynaptic toxicity, but no platelet function. On the contrary, the acidic PLA2 can inhibit the platelet aggregation, but</description><identifier>ISSN: 2095-9273</identifier><language>eng</language><subject>aggregation ; crystal ; inhibitor ; phospholipase ; platelet ; protein</subject><ispartof>中国科学通报：英文版, 1992 (16), p.1394-1396</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttp://image.cqvip.com/vip1000/qk/86894X/86894X.jpg</thumbnail><link.rule.ids>314,780,784,4024</link.rule.ids></links><search><creatorcontrib>桂璐璐 牛秀田 毕汝昌 林政炯 陈远聪</creatorcontrib><title>PRELIMINARY CRYSTALLOGRAPHIC STUDY OF THE PLATELET AGGREGATION INHIBITOR FROM THE VENOM OF Agkistrodon halys Pallas</title><title>中国科学通报：英文版</title><addtitle>Chinese Science Bulletin</addtitle><description>In addition to esterasic activity, phospholipase A2 （PLA2） from snake venom possesses various physiological activities and toxicities, such as hemolysis, anticoagulation, platelet function, presynaptic toxicity, muscular toxicity. It has been found that the venom from Agkistrodon halys Pallas has three homologous PLA2, which are quite different from each other in enzymatic activity, presynaptic toxicity, platelet function, hemolysis and anticoagulation. For example, the neutral PLA2 has strong presynaptic toxicity, but no platelet function. On the contrary, the acidic PLA2 can inhibit the platelet aggregation, but</description><subject>aggregation</subject><subject>crystal</subject><subject>inhibitor</subject><subject>phospholipase</subject><subject>platelet</subject><subject>protein</subject><issn>2095-9273</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1992</creationdate><recordtype>article</recordtype><recordid>eNqNi08LgjAcQHcoKMrv8IPOwbRMPC6bOphO1go8xeiPWabluvjtk-gDdHrv8N4AjR3su3Pf8RYjZBlzwxjbS99ZYm-MTCYpZwlLicwhkPlWEc5FJEkWswC2arfJQYSgYgoZJ4pyqoBEkaQRUUykwNKYrZkSEkIpkm-3p2lv_USKe2nebXNqarjqqjOQ6arSZoqGF12Zs_XjBM1CqoJ4frw2dfEq6-LwbMuHbruDjbFruyvPw4v_qg9200MY</recordid><startdate>1992</startdate><enddate>1992</enddate><creator>桂璐璐 牛秀田 毕汝昌 林政炯 陈远聪</creator><scope>2RA</scope><scope>92L</scope><scope>CQIGP</scope><scope>~WA</scope></search><sort><creationdate>1992</creationdate><title>PRELIMINARY CRYSTALLOGRAPHIC STUDY OF THE PLATELET AGGREGATION INHIBITOR FROM THE VENOM OF Agkistrodon halys Pallas</title><author>桂璐璐 牛秀田 毕汝昌 林政炯 陈远聪</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-chongqing_primary_10051567703</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1992</creationdate><topic>aggregation</topic><topic>crystal</topic><topic>inhibitor</topic><topic>phospholipase</topic><topic>platelet</topic><topic>protein</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>桂璐璐 牛秀田 毕汝昌 林政炯 陈远聪</creatorcontrib><collection>维普_期刊</collection><collection>中文科技期刊数据库-CALIS站点</collection><collection>维普中文期刊数据库</collection><collection>中文科技期刊数据库- 镜像站点</collection><jtitle>中国科学通报：英文版</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>桂璐璐 牛秀田 毕汝昌 林政炯 陈远聪</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>PRELIMINARY CRYSTALLOGRAPHIC STUDY OF THE PLATELET AGGREGATION INHIBITOR FROM THE VENOM OF Agkistrodon halys Pallas</atitle><jtitle>中国科学通报：英文版</jtitle><addtitle>Chinese Science Bulletin</addtitle><date>1992</date><risdate>1992</risdate><issue>16</issue><spage>1394</spage><epage>1396</epage><pages>1394-1396</pages><issn>2095-9273</issn><abstract>In addition to esterasic activity, phospholipase A2 （PLA2） from snake venom possesses various physiological activities and toxicities, such as hemolysis, anticoagulation, platelet function, presynaptic toxicity, muscular toxicity. It has been found that the venom from Agkistrodon halys Pallas has three homologous PLA2, which are quite different from each other in enzymatic activity, presynaptic toxicity, platelet function, hemolysis and anticoagulation. For example, the neutral PLA2 has strong presynaptic toxicity, but no platelet function. On the contrary, the acidic PLA2 can inhibit the platelet aggregation, but</abstract></addata></record>
fulltext fulltext
identifier ISSN: 2095-9273
ispartof 中国科学通报：英文版, 1992 (16), p.1394-1396
issn 2095-9273
language eng
recordid cdi_chongqing_primary_1005156770
source Alma/SFX Local Collection
subjects aggregation
crystal
inhibitor
phospholipase
platelet
protein
title PRELIMINARY CRYSTALLOGRAPHIC STUDY OF THE PLATELET AGGREGATION INHIBITOR FROM THE VENOM OF Agkistrodon halys Pallas
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-20T18%3A03%3A51IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-chongqing&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=PRELIMINARY%20CRYSTALLOGRAPHIC%20STUDY%20OF%20THE%20PLATELET%20AGGREGATION%20INHIBITOR%20FROM%20THE%20VENOM%20OF%20Agkistrodon%20halys%20Pallas&rft.jtitle=%E4%B8%AD%E5%9B%BD%E7%A7%91%E5%AD%A6%E9%80%9A%E6%8A%A5%EF%BC%9A%E8%8B%B1%E6%96%87%E7%89%88&rft.au=%E6%A1%82%E7%92%90%E7%92%90%20%E7%89%9B%E7%A7%80%E7%94%B0%20%E6%AF%95%E6%B1%9D%E6%98%8C%20%E6%9E%97%E6%94%BF%E7%82%AF%20%E9%99%88%E8%BF%9C%E8%81%AA&rft.date=1992&rft.issue=16&rft.spage=1394&rft.epage=1396&rft.pages=1394-1396&rft.issn=2095-9273&rft_id=info:doi/&rft_dat=%3Cchongqing%3E1005156770%3C/chongqing%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rft_cqvip_id=1005156770&rfr_iscdi=true