Platelet thromboxane(11-dehydro-Thromboxane B2) and aspirin response in patients with diabetes and coronary artery disease

Aspirin(ASA) irreversibly inhibits platelet cyclooxygenase-1(COX-1) leading to decreased thromboxane-mediated platelet activation. The effect of ASA ingestion on thromboxane generation was evaluated in patients with diabetes(DM) and cardiovascular disease. Thromboxane inhibition was assessed by meas...

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Veröffentlicht in:世界糖尿病杂志:英文版(电子版) 2014 (2), p.115-127
1. Verfasser: Luis R Lopez Kirk E Guyer Ignacio Garcia De La Torre Kelly R Pitts Eiji Matsuura Paul RJ Ames
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Sprache:eng
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