EFFECTS OF BU GU ZHI(PSORALEA CORYLIFOLIA L) AND BAI ZHI(DAHURIAN ANGELICA ROOT) EXTRACTS ON MELANOCYTE ADHESION AND MIGRATION

Vitiligoisacommonskindiseaesmanifestedby depigmentedwhitepatchessurroundedbyanormal orahyperpigmentedborder,causedbymelanocyte selectivilydestroy[1].Melanocyteishappenedby theneuralcrest,whichwouldmigratedtobasallay erofepidermisandhairfolliculuspilibywayof dorso lateralmethodinnormalperson,willbeacti vatedandmultiplicatedandmigratedtoepidermle sioninperiodofvitiligorecovery[2].Thoughthe traditionalChinesemedicinehasbettercurative effectintreatingthevitiligo,molecularmechanism controlsmelanocyteresponses...