MicroRNA-221 inhibits CDKNIC/p57 expression in human colorectal carcinoma

Aim: To investigate the regulatory effect of microRNA-221 (miR-221) on CDKN1C/p57 expression in colorectal carcinoma (CRC). Methods: Thirty four CRC and adjacent non-tumorous tissue samples were collected individually. Total RNA and protein were isolatedand from these samples and four human CRC-deri...

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Veröffentlicht in:Acta pharmacologica Sinica 2011, Vol.32 (3), p.375-384
1. Verfasser: Kai SUN Wei WANG Jun-jie ZENG Cheng-tang WU Shang-tong LEI Guo-xin LI
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Sprache:eng
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