Inhibitory effects of coronary vasodilator papaverine on heterologouslyexpressed HERG currents in Xenopus oocytes

Aim： To characterize the effects of papaverine on HERG channels expressed in Xenopus oocytes as well as cardiac action potential in rabbit ventricular myocytes. Methods： Conventional microelectrodes were used to record action potential in rabbit ventricular myocytes. HERG currents were recorded by 2...

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Veröffentlicht in:	Acta pharmacologica Sinica 2007, Vol.28 (4), p.503-510
1. Verfasser:	Cuk-seong KIM Nam LEE Sook-jin SON Kyu-seung LEE Hyo-shin KIM Yong-geun KWAK Soo-wan CHAE Sang-doLEE Byeong-hwa JEON Jin-bong PARK
Format:	Artikel
Sprache:	eng
Schlagworte:	HERG通道电流 冠状动脉血管扩张药物 卵母细胞 心脏动作电位 抑制作用 罂粟碱
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