Engagement of PSGL-1 enhances β2-integrin-involved adhesion of neutrophils to recombinant ICAM-1

Aim: The interactions of selectins and their ligands initiate the process of leukocyte migrating into inflamed tissue. P-selectin glycoprotein ligand 1 (PSGL-1) is the best characterized ligand of selectins, and has been demonstrated to mediate the adhesion of leukocytes to all three selectins in vi...

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Veröffentlicht in:Acta pharmacologica Sinica 2006-05, Vol.27 (5), p.617-622
1. Verfasser: Xiao-guang WANG Yan-ping CHENG Xue-qing BA
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Sprache:eng
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