Bactericidal, protistocidal, nematodicidal properties and chemical composition of ethanol extract of Punica granatum peel

We have studied the chemical composition and antibacterial profile of ethanolic extract of Punica granatum L. (Lythraceae) on strains of microorganisms in vitro. Analysis using GC-MS showed 5-hydroxymethylfurfural (36.6%), D-sucrose (23.2%), sorbitol (6.7%), palmitic acid β-monoglyceride (5.6%), 2-f...

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Veröffentlicht in:Biosystems diversity 2019-01, Vol.27 (3), p.300-306
Hauptverfasser: Palchykov, V.A, Zazharskiy, V. V, Brygadyrenko, V. V, Davydenko, P. O, Kulishenko, O.M, Borovik, I.V, Chumak, V, Kryvaya, A, Boyko, O. O
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container_end_page 306
container_issue 3
container_start_page 300
container_title Biosystems diversity
container_volume 27
creator Palchykov, V.A
Zazharskiy, V. V
Brygadyrenko, V. V
Davydenko, P. O
Kulishenko, O.M
Borovik, I.V
Chumak, V
Kryvaya, A
Boyko, O. O
description We have studied the chemical composition and antibacterial profile of ethanolic extract of Punica granatum L. (Lythraceae) on strains of microorganisms in vitro. Analysis using GC-MS showed 5-hydroxymethylfurfural (36.6%), D-sucrose (23.2%), sorbitol (6.7%), palmitic acid β-monoglyceride (5.6%), 2-furancarboxaldehyde (3.5%) and β-D-glucopyranose (3.3%) as the major components of the title extract. The experiment revealed a positive antibacterial effect of extracts obtained from P. granatum on 14 strains specifically Enterobacteriaceae microorganisms (Escherichia coli, Enterobacter aegorenеs, Proteus vulgaris, Serratia marcescens, Klebsiella pneumonia), Listeriaceae (Listeria ivanovi, L. іnnocua, L. monocytogenes) and yeasts from the family Saccharomycetaceae (Candida albicans). Our study showed that in many cases these extracts more intensively affect multi-resistant strains of microorganisms than macrolide antibiotic azithromycin and is therefore a source of molecules to be exploited in medicine or by the pharmaceutical industry.
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subjects Evaluation research
pomegranate
bactericidal action
gas chromatography-mass spectrometry (gc-ms)
5-hydroxymethylfurfural
d-sucrose
sorbitol
title Bactericidal, protistocidal, nematodicidal properties and chemical composition of ethanol extract of Punica granatum peel
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