Improving the Lethal Effect of Cpl-7, a Pneumococcal Phage Lysozyme with Broad Bactericidal Activity, by Inverting the Net Charge of Its Cell Wall-Binding Module

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Veröffentlicht in:	Antimicrobial Agents and Chemotherapy 2013-11, Vol.57 (11), p.5355-5365
Hauptverfasser:	DIEZ-MARTINEZ, Roberto, DE PAZ, Héctor, BUSTAMANTE, Noemí, GARCIA, Ernesto, MENENDEZ, Margarita, GARCIA, Pedro
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Substitution Animals Antibiotics. Antiinfectious agents. Antiparasitic agents Bacterial diseases Biological and medical sciences Cell Wall - drug effects Cell Wall - metabolism Cell Wall - virology Choline - metabolism Danio rerio Embryo, Nonmammalian - drug effects Embryo, Nonmammalian - microbiology Escherichia coli Escherichia coli - drug effects Escherichia coli - pathogenicity Escherichia coli - virology Experimental Therapeutics Human bacterial diseases Infectious diseases Medical sciences Monoterpenes - pharmacology Muramidase Muramidase - genetics Muramidase - metabolism Muramidase - pharmacology Pharmacology. Drug treatments Protein Binding Protein Engineering Pseudomonas putida Pseudomonas putida - drug effects Pseudomonas putida - pathogenicity Pseudomonas putida - virology Staphylococcal infections, streptococcal infections, pneumococcal infections Static Electricity Streptococcus Phages Streptococcus Phages - enzymology Streptococcus Phages - genetics Streptococcus pneumoniae Streptococcus pneumoniae - drug effects Streptococcus pneumoniae - pathogenicity Streptococcus pneumoniae - virology Streptococcus pyogenes Streptococcus pyogenes - drug effects Streptococcus pyogenes - pathogenicity Streptococcus pyogenes - virology Viral Proteins Viral Proteins - genetics Viral Proteins - metabolism Viral Proteins - pharmacology Zebrafish - embryology Zebrafish - microbiology
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