Pharmacokinetics, Safety, and Tolerability of GS-9851, a Nucleotide Analog Polymerase Inhibitor for Hepatitis C Virus, following Single Ascending Doses in Healthy Subjects

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Veröffentlicht in:	Antimicrobial Agents and Chemotherapy 2013-03, Vol.57 (3), p.1201-1208
Hauptverfasser:	DENNING, Jill, CORNPROPST, Melanie, FLACH, Stephen D, BERREY, Michelle M, SYMONDS, William T
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Adolescent Adult Aged Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral Agents Antiviral Agents - blood Antiviral Agents - pharmacokinetics Antiviral Agents - pharmacology Area Under Curve Biological and medical sciences Dose-Response Relationship, Drug Double-Blind Method Drug Administration Schedule Female Half-Life Hepacivirus Hepacivirus - drug effects Hepacivirus - growth & development Hepatitis C virus Hepatitis C, Chronic Hepatitis C, Chronic - drug therapy Hepatitis C, Chronic - virology Human viral diseases Humans Infectious diseases Male Medical sciences Middle Aged Nucleotides Nucleotides - blood Nucleotides - pharmacokinetics Nucleotides - pharmacology Pharmacology. Drug treatments Placebos RNA, Viral RNA, Viral - antagonists & inhibitors RNA, Viral - biosynthesis Viral diseases Viral hepatitis Viral Load - drug effects
Online-Zugang:	Volltext
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