The Naphthyridinone GSK364735 Is a Novel, Potent Human Immunodeficiency Virus Type 1 Integrase Inhibitor and Antiretroviral

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Veröffentlicht in:	Antimicrobial Agents and Chemotherapy 2008-03, Vol.52 (3), p.901-908
Hauptverfasser:	GARVEY, Edward P, JOHNS, Brian A, WEATHERHEAD, Jason G, KOBLE, Cecilia S, ALIEN, Scott H, SCHALLER, Lee T, SHERRILL, Ronald G, YOSHINAGA, Tomokazu, KOBAYASHI, Masanori, WAKASA-MORIMOTO, Chiaki, MIKI, Shigeru, NAKAHARA, Koichiro, GARTLAND, Margaret J, NOSHI, Takeshi, SATO, Akihiko, FUJIWARA, Tamio, FOSTER, Scott A, MILLER, Wayne H, FERRIS, Robert G, HAZEN, Richard J, UNDERWOOD, Mark R, BOROS, Eric E, THOMPSON, James B
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-HIV Agents - pharmacology Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral Agents Biological and medical sciences Cell Line Cells, Cultured Drug Resistance, Viral Drug Synergism HIV Integrase HIV Integrase - drug effects HIV Integrase - genetics HIV Integrase Inhibitors HIV Integrase Inhibitors - pharmacology HIV Protease Inhibitors - pharmacology HIV-1 HIV-1 - drug effects HIV-1 - enzymology HIV-1 - physiology Human immunodeficiency virus Human immunodeficiency virus 1 Human immunodeficiency virus 2 Human viral diseases Humans Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunopathology Infectious diseases Leukocytes, Mononuclear - virology Medical sciences Microbial Sensitivity Tests - methods Mutation Naphthyridines Naphthyridines - pharmacology Pharmacology. Drug treatments Reverse Transcriptase Inhibitors - pharmacology Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Virus Integration - drug effects Virus Replication - drug effects
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