ROC Analysis and a Realistic Model of Heart Rate Variability

We have carried out a pilot study on a standard collection of electrocardiograms from patients who suffer from congestive heart failure, and subjects without cardiac pathology, using receiver-operating-characteristic (ROC) analysis. The scale-dependent wavelet-coefficient standard deviation \sigma_{...

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Hauptverfasser: Thurner, Stefan, Feurstein, Markus C, Teich, Malvin C
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Teich, Malvin C
description We have carried out a pilot study on a standard collection of electrocardiograms from patients who suffer from congestive heart failure, and subjects without cardiac pathology, using receiver-operating-characteristic (ROC) analysis. The scale-dependent wavelet-coefficient standard deviation \sigma_{wav}(m), a multiresolution-based analysis measure, is found to be superior to two commonly used measures of cardiac dysfunction when the two classes of patients cannot be completely separated. A jittered integrate-and-fire model with a fractal Gaussian-noise kernel provides a realistic simulation of heartbeat sequences for both heart-failure patients and normal subjects.
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subjects Physics - Chaotic Dynamics
Quantitative Biology - Biomolecules
Quantitative Biology - Cell Behavior
Quantitative Biology - Genomics
Quantitative Biology - Molecular Networks
Quantitative Biology - Neurons and Cognition
Quantitative Biology - Other
Quantitative Biology - Populations and Evolution
Quantitative Biology - Quantitative Methods
Quantitative Biology - Subcellular Processes
Quantitative Biology - Tissues and Organs
title ROC Analysis and a Realistic Model of Heart Rate Variability
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