A data-informed mathematical model of microglial cell dynamics during ischemic stroke in the middle cerebral artery

Neuroinflammation immediately follows the onset of ischemic stroke in the middle cerebral artery. During this process, microglial cells are activated in and recruited to the penumbra. Microglial cells can be activated into two different phenotypes: M1, which can worsen brain injury; or M2, which can...

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Hauptverfasser: Amato, Sara, Arnold, Andrea
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Sprache:eng
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