Sample size calculation based on the difference in restricted mean time lost for clinical trials with competing risks

Computation of sample size is important when designing clinical trials. The presence of competing risks makes the design of clinical trials with time-to-event endpoints cumbersome. A model based on the subdistribution hazard ratio (SHR) is commonly used for trials under competing risks. However, thi...

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Hauptverfasser: Geng, Xiang, Li, Zhaojin, Zhang, Chengfeng, Wang, Yanjie, Shen, Haoning, Huang, Zhiheng, Hou, Yawen, Chen, Zheng
Format: Artikel
Sprache:eng
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