A comprehensive comparison of tools for fitting mutational signatures

Mutational signatures connect characteristic mutational patterns in the genome with biological or chemical processes that take place in cancers. Analysis of mutational signatures can help elucidate tumor evolution, prognosis, and therapeutic strategies. Although tools for extracting mutational signa...

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Veröffentlicht in:	arXiv.org 2024-12
Hauptverfasser:	Medo, Matúš, Ng, Charlotte K Y, Medová, Michaela
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological activity Cancer Empirical analysis Mutation Performance evaluation Quantitative Biology - Genomics Quantitative Biology - Quantitative Methods Signatures Tumors
Online-Zugang:	Volltext
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