Case Weighted Adaptive Power Priors for Hybrid Control Analyses with Time-to-Event Data

We develop a method for hybrid analyses that uses external controls to augment internal control arms in randomized controlled trials (RCT) where the degree of borrowing is determined based on similarity between RCT and external control patients to account for systematic differences (e.g. unmeasured...

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Hauptverfasser: Kwiatkowski, Evan, Zhu, Jiawen, Li, Xiao, Pang, Herbert, Lieberman, Grazyna, Psioda, Matthew A
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Sprache:eng
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