Integrating molecular models into CryoEM heterogeneity analysis using scalable high-resolution deep Gaussian mixture models

Resolving the structural variability of proteins is often key to understanding the structure-function relationship of those macromolecular machines. Single particle analysis using Cryogenic electron microscopy (CryoEM), combined with machine learning algorithms, provides a way to reveal the dynamics...

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Hauptverfasser: Chen, Muyuan, Toader, Bogdan, Lederman, Roy
Format: Artikel
Sprache:eng
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