Tau affects P53 function and cell fate during the DNA damage response

Cells are constantly exposed to DNA damaging insults. To protect the organism, cells developed a complex molecular response coordinated by P53, the master regulator of DNA repair, cell division and cell fate. DNA damage accumulation and abnormal cell fate decision may represent a pathomechanism shar...

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Veröffentlicht in:	arXiv.org 2020-04
Hauptverfasser:	Sola, Martina, Magrin, Claudia, Giona Pedrioli, Pinton, Sandra, Salvade, Agnese, Papin, Stephanie, Paganetti, Paolo
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer Cell death Cellular communication Damage accumulation Deoxyribonucleic acid Depletion DNA DNA damage Quantitative Biology - Cell Behavior
Online-Zugang:	Volltext
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