Classification of large DNA methylation datasets for identifying cancer drivers

DNA methylation is a well-studied genetic modification crucial to regulate the functioning of the genome. Its alterations play an important role in tumorigenesis and tumor-suppression. Thus, studying DNA methylation data may help biomarker discovery in cancer. Since public data on DNA methylation be...

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Veröffentlicht in:	arXiv.org 2018-04
Hauptverfasser:	Celli, Fabrizio, Cumbo, Fabio, Weitschek, Emanuel
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Biomarkers Cancer Classification Computer Science - Computational Engineering, Finance, and Science Data management Datasets Deletion Deoxyribonucleic acid DNA DNA methylation Experiments Feature extraction Genes Genetic modification Genomes Iterative methods Network analysis Quantitative Biology - Genomics Tumors
Online-Zugang:	Volltext
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