Interplay between membrane elasticity and active cytoskeleton forces regulates the aggregation dynamics of the immunological synapse

Soft Matter 13, 6938 (2017) Adhesion between a T cell and an antigen presenting cell is achieved by TCR-pMHC and LFA1-ICAM1 protein complexes. These segregate to form a special pattern, known as the immunological synapse (IS), consisting of a central quasi-circular domain of TCR-pMHC bonds surrounde...

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Hauptverfasser:	Dharan, Nadiv, Farago, Oded
Format:	Artikel
Sprache:	eng
Schlagworte:	Physics - Biological Physics Physics - Soft Condensed Matter
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