Pulsatile Drug Delivery System Based on Electrohydrodynamic Method
Electrohydrodynamic (EHD) generation, a commonly used method in BioMEMS, plays a significant role in the pulsatile drug delivery system for a decade. In this paper, an EHD based drug delivery system is well designed, which can be used to generate a single drug droplet as small as 2.83 nL in 8.5 ms w...
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| creator | Zheng, Yi Zhang, Yuan Hu, Junqiang Gao, Wenle |
| description | Electrohydrodynamic (EHD) generation, a commonly used method in BioMEMS,
plays a significant role in the pulsatile drug delivery system for a decade. In
this paper, an EHD based drug delivery system is well designed, which can be
used to generate a single drug droplet as small as 2.83 nL in 8.5 ms with a
total device of 2\times2\times3 mm^3, and an external supplied voltage of 1500
V. Theoretically, we derive the expressions for the size and the formation time
of a droplet generated by EHD method, while taking into account the drug supply
rate, properties of liquid, gap between two electrodes, nozzle size, and
charged droplet neutralization. This work proves a repeatable, stable and
controllable droplet generation and delivery system based on EHD method
experimentally as well as theoretically. |
| doi_str_mv | 10.48550/arxiv.1207.1844 |
| format | Article |
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plays a significant role in the pulsatile drug delivery system for a decade. In
this paper, an EHD based drug delivery system is well designed, which can be
used to generate a single drug droplet as small as 2.83 nL in 8.5 ms with a
total device of 2\times2\times3 mm^3, and an external supplied voltage of 1500
V. Theoretically, we derive the expressions for the size and the formation time
of a droplet generated by EHD method, while taking into account the drug supply
rate, properties of liquid, gap between two electrodes, nozzle size, and
charged droplet neutralization. This work proves a repeatable, stable and
controllable droplet generation and delivery system based on EHD method
experimentally as well as theoretically.</description><identifier>DOI: 10.48550/arxiv.1207.1844</identifier><language>eng</language><subject>Physics - Fluid Dynamics ; Physics - Medical Physics</subject><creationdate>2012-07</creationdate><rights>http://arxiv.org/licenses/nonexclusive-distrib/1.0</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>228,230,776,881</link.rule.ids><linktorsrc>$$Uhttps://arxiv.org/abs/1207.1844$$EView_record_in_Cornell_University$$FView_record_in_$$GCornell_University$$Hfree_for_read</linktorsrc><backlink>$$Uhttps://doi.org/10.48550/arXiv.1207.1844$$DView paper in arXiv$$Hfree_for_read</backlink></links><search><creatorcontrib>Zheng, Yi</creatorcontrib><creatorcontrib>Zhang, Yuan</creatorcontrib><creatorcontrib>Hu, Junqiang</creatorcontrib><creatorcontrib>Gao, Wenle</creatorcontrib><title>Pulsatile Drug Delivery System Based on Electrohydrodynamic Method</title><description>Electrohydrodynamic (EHD) generation, a commonly used method in BioMEMS,
plays a significant role in the pulsatile drug delivery system for a decade. In
this paper, an EHD based drug delivery system is well designed, which can be
used to generate a single drug droplet as small as 2.83 nL in 8.5 ms with a
total device of 2\times2\times3 mm^3, and an external supplied voltage of 1500
V. Theoretically, we derive the expressions for the size and the formation time
of a droplet generated by EHD method, while taking into account the drug supply
rate, properties of liquid, gap between two electrodes, nozzle size, and
charged droplet neutralization. This work proves a repeatable, stable and
controllable droplet generation and delivery system based on EHD method
experimentally as well as theoretically.</description><subject>Physics - Fluid Dynamics</subject><subject>Physics - Medical Physics</subject><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>GOX</sourceid><recordid>eNotz7tuwjAUgGEvDBXt3qnyCyTEd2csl14kEJVgjw72CVhySOUEVL99Rcv0b7_0EfLMqlJapaoZpJ9wLRmvTMmslA9k_nWJA4whIl2my5EuMYYrpkx3eRixo3MY0NP-TFcR3Zj6U_ap9_kMXXB0g-Op949k0kIc8OneKdm_rfaLj2K9ff9cvK4L0EoW2jHOpfVaOotCgQLuuDKyFlY4c-CeG21BexDOCyas04AH0zJvdA1tbcSUvPxv_wzNdwodpNzcLM3NIn4BQvVEIA</recordid><startdate>20120708</startdate><enddate>20120708</enddate><creator>Zheng, Yi</creator><creator>Zhang, Yuan</creator><creator>Hu, Junqiang</creator><creator>Gao, Wenle</creator><scope>GOX</scope></search><sort><creationdate>20120708</creationdate><title>Pulsatile Drug Delivery System Based on Electrohydrodynamic Method</title><author>Zheng, Yi ; Zhang, Yuan ; Hu, Junqiang ; Gao, Wenle</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a654-6c12248d64c8e35a5a2c25749383c7b2d2768a6da3cd3138c6aeb7f1d769af973</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Physics - Fluid Dynamics</topic><topic>Physics - Medical Physics</topic><toplevel>online_resources</toplevel><creatorcontrib>Zheng, Yi</creatorcontrib><creatorcontrib>Zhang, Yuan</creatorcontrib><creatorcontrib>Hu, Junqiang</creatorcontrib><creatorcontrib>Gao, Wenle</creatorcontrib><collection>arXiv.org</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Zheng, Yi</au><au>Zhang, Yuan</au><au>Hu, Junqiang</au><au>Gao, Wenle</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pulsatile Drug Delivery System Based on Electrohydrodynamic Method</atitle><date>2012-07-08</date><risdate>2012</risdate><abstract>Electrohydrodynamic (EHD) generation, a commonly used method in BioMEMS,
plays a significant role in the pulsatile drug delivery system for a decade. In
this paper, an EHD based drug delivery system is well designed, which can be
used to generate a single drug droplet as small as 2.83 nL in 8.5 ms with a
total device of 2\times2\times3 mm^3, and an external supplied voltage of 1500
V. Theoretically, we derive the expressions for the size and the formation time
of a droplet generated by EHD method, while taking into account the drug supply
rate, properties of liquid, gap between two electrodes, nozzle size, and
charged droplet neutralization. This work proves a repeatable, stable and
controllable droplet generation and delivery system based on EHD method
experimentally as well as theoretically.</abstract><doi>10.48550/arxiv.1207.1844</doi><oa>free_for_read</oa></addata></record> |
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| subjects | Physics - Fluid Dynamics Physics - Medical Physics |
| title | Pulsatile Drug Delivery System Based on Electrohydrodynamic Method |
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