Small Angle X‑ray Scattering-Based Elucidation of the Self-Association Mechanism of Human Insulin Analogue LysB29(Nεω‑carboxyheptadecanoyl) des(B30)

LysB29(Nεω-carboxyheptadecanoyl) des(B30) human insulin is an insulin analogue belonging to a class of analogues designed to form soluble depots in subcutis by self-association, aiming at a protracted action. On the basis of small angle X-ray scattering (SAXS) supplemented by a range of biophysical...

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Veröffentlicht in:Biochemistry (Easton) 2013-01, Vol.52 (2), p.282-294
Hauptverfasser: Jensen, Malene Hillerup, Wahlund, Per-Olof, Toft, Katrine Nørgaard, Jacobsen, Jes Kristian, Steensgaard, Dorte Bjerre, van de Weert, Marco, Havelund, Svend, Vestergaard, Bente
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Sprache:eng
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