New Selective Inhibitors of ERG Positive Prostate Cancer: ERGi-USU‑6 Salt Derivatives

Prostate cancer is among the leading causes of cancer related death of men in the United States. The ERG gene fusion leading to overexpression of near full-length ERG transcript and protein represents most prevalent (50–65%) prostate cancer driver gene alterations. The ERG oncoprotein overexpression...

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Veröffentlicht in:	ACS medicinal chemistry letters 2021-11, Vol.12 (11), p.1703-1709
Hauptverfasser:	Eldhose, Binil, Pandrala, Mallesh, Xavier, Charles, Mohamed, Ahmed A, Srivastava, Shiv, Sunkara, Anu D, Dobi, Albert, Malhotra, Sanjay V
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemistry, Medicinal Letter Life Sciences & Biomedicine Pharmacology & Pharmacy Science & Technology
Online-Zugang:	Volltext
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