Ferroptosis-Strengthened Metabolic and Inflammatory Regulation of Tumor-Associated Macrophages Provokes Potent Tumoricidal Activities

Modulation of tumor-associated macrophages (TAMs) holds promise for cancer treatment, mainly relying on M1 signaling activation and pro-inflammatory promotion. Nevertheless, the antitumor activity is often limited by the anti-inflammatory factors in the tumor microenvironment. Moreover, the metaboli...

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Veröffentlicht in:Nano letters 2021-08, Vol.21 (15), p.6471-6479
Hauptverfasser: Gu, Zhengying, Liu, Tianqing, Liu, Chao, Yang, Yannan, Tang, Jie, Song, Hao, Wang, Yue, Yang, Yang, Yu, Chengzhong
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Sprache:eng
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