Transcriptional repression of NFKBIA triggers constitutive IKK‐ and proteasome‐independent p65/RelA activation in senescence von Kolesnichenko, Marina, Mikuda, Nadine, Höpken, Uta E, Kärgel, Eva, Uyar, Bora, Tufan, Ahmet Bugra, Milanovic, Maja, Sun, Wei, Krahn, Inge, Schleich, Kolja, von Hoff, Linda, Hinz, Michael, Willenbrock, Michael, Jungmann, Sabine, Akalin, Altuna, Lee, Soyoung, Schmidt‐Ullrich, Ruth, Schmitt, Clemens A, Scheidereit, Claus

Volltext

The AP-1-BATF and -BATF3 module is essential for growth, survival and TH17/ILC3 skewing of anaplastic large cell lymphoma von Schleussner, Nikolai, Merkel, Olaf, Costanza, Mariantonia, Liang, Huan-Chang, Hummel, Franziska, Romagnani, Chiara, Durek, Pawel, Anagnostopoulos, Ioannis, Hummel, Michael, Jöhrens, Korinna, Niedobitek, Antonia, Griffin, Patrick R., Piva, Roberto, Sczakiel, Henrike L., Woessmann, Wilhelm, Damm-Welk, Christine, Hinze, Christian, Stoiber, Dagmar, Gillissen, Bernd, Turner, Suzanne D., Kaergel, Eva, von Hoff, Linda, Grau, Michael, Lenz, Georg, Dörken, Bernd, Scheidereit, Claus, Kenner, Lukas, Janz, Martin, Mathas, Stephan

Volltext

Autocrine LTA signaling drives NF-κB and JAK-STAT activity and myeloid gene expression in Hodgkin lymphoma von von Hoff, Linda, Kärgel, Eva, Franke, Vedran, McShane, Erik, Schulz-Beiss, Kathrin W., Patone, Giannino, Schleussner, Nikolai, Kolesnichenko, Marina, Hübner, Norbert, Daumke, Oliver, Selbach, Matthias, Akalin, Altuna, Mathas, Stephan, Scheidereit, Claus

Volltext

The AP-1-BATF and -BATF3 module is essential for growth, survival and TH17/ILC3 skewing of anaplastic large cell lymphoma von Schleussner, Nikolai, Merkel, Olaf, Costanza, Mariantonia, Liang, Huan-Chang, Hummel, Franziska, Romagnani, Chiara, Durek, Pawel, Anagnostopoulos, Ioannis, Hummel, Michael, Jöhrens, Korinna, Niedobitek, Antonia, Griffin, Patrick R, Piva, Roberto, Sczakiel, Henrike L, Woessmann, Wilhelm, Damm-Welk, Christine, Hinze, Christian, Stoiber, Dagmar, Gillissen, Bernd, Turner, Suzanne D, Kaergel, Eva, von Hoff, Linda, Grau, Michael, Lenz, Georg, Dörken, Bernd, Scheidereit, Claus, Kenner, Lukas, Janz, Martin, Mathas, Stephan

Volltext bestellen

Small molecule targeting of transcription-replication conflict for selective chemotherapy von Gu, Long, Li, Min, Li, Caroline M., Haratipour, Pouya, Lingeman, Robert, Jossart, Jennifer, Gutova, Margarita, Flores, Linda, Hyde, Caitlyn, Kenjić, Nikola, Li, Haiqing, Chung, Vincent, Li, Hongzhi, Lomenick, Brett, Von Hoff, Daniel D., Synold, Timothy W., Aboody, Karen S., Liu, Yilun, Horne, David, Hickey, Robert J., Perry, J. Jefferson P., Malkas, Linda H.

Volltext

Nanoliposomal irinotecan with fluorouracil and folinic acid in metastatic pancreatic cancer after previous gemcitabine-based therapy (NAPOLI-1): a global, randomised, open-label, p... von Wang-Gillam, Andrea, MD, Li, Chung-Pin, Prof, Bodoky, György, Prof, Dean, Andrew, MD, Shan, Yan-Shen, Prof, Jameson, Gayle, MSN, Macarulla, Teresa, MD, Lee, Kyung-Hun, MD, Cunningham, David, Prof, Blanc, Jean F, Prof, Hubner, Richard A, PhD, Chiu, Chang-Fang, Prof, Schwartsmann, Gilberto, MD, Siveke, Jens T, Prof, Braiteh, Fadi, MD, Moyo, Victor, MBBCh, Belanger, Bruce, PhD, Dhindsa, Navreet, DDS, Bayever, Eliel, MBBCh, Von Hoff, Daniel D, Prof, Chen, Li-Tzong, Prof

Volltext

randomized phase II study of PX-12, an inhibitor of thioredoxin in patients with advanced cancer of the pancreas following progression after a gemcitabine-containing combination von Ramanathan, Ramesh K, Abbruzzese, James, Dragovich, Tomislav, Kirkpatrick, Lynn, Guillen, Jose M, Baker, Amanda F, Pestano, Linda A, Green, Sylvan, Von Hoff, Daniel D

Volltext

E6201, an intravenous MEK1 inhibitor, achieves an exceptional response in BRAF V600E-mutated metastatic malignant melanoma with brain metastases von Babiker, Hani M., Byron, Sara A., Hendricks, William P. D., Elmquist, William F., Gampa, Gautham, Vondrak, Jessica, Aldrich, Jessica, Cuyugan, Lori, Adkins, Jonathan, De Luca, Valerie, Tibes, Raoul, Borad, Mitesh J., Marceau, Katie, Myers, Thomas J., Paradiso, Linda J., Liang, Winnie S., Korn, Ronald L., Cridebring, Derek, Von Hoff, Daniel D., Carpten, John D., Craig, David W., Trent, Jeffrey M., Gordon, Michael S.

Volltext

A Phase I Pharmacokinetic Study of HMN-214, a Novel Oral Stilbene Derivative with Polo-Like Kinase-1–Interacting Properties, in Patients with Advanced Solid Tumors von GARLAND, Linda L, TAYLOR, Charles, PILKINGTON, Deborah L, COHEN, Jan L, VON HOFF, Daniel D

Volltext

Traces of Trauma: A Multivariate Pattern Analysis of Childhood Trauma, Brain Structure, and Clinical Phenotypes von Popovic, David, Ruef, Anne, Dwyer, Dominic B., Antonucci, Linda A., Sanfelici, Rachele, Kambeitz-Ilankovic, Lana, Dong, Mark S., Paul, Riya, Paolini, Marco, Hedderich, Dennis, Haidl, Theresa, Kambeitz, Joseph, Ruhrmann, Stephan, Chisholm, Katharine, Schultze-Lutter, Frauke, Falkai, Peter, Pergola, Giulio, Blasi, Giuseppe, Bertolino, Alessandro, Lencer, Rebekka, Dannlowski, Udo, Upthegrove, Rachel, Salokangas, Raimo K.R., Pantelis, Christos, Meisenzahl, Eva, Wood, Stephen J., Brambilla, Paolo, Koutsouleris, Nikolaos, Dong, Mark Sen, Erkens, Anne, Gussmann, Eva, Haas, Shalaila, Hasan, Alkomiet, Hoff, Claudius, Khanyaree, Ifrah, Melo, Aylin, Köhler, Janis, Öztürk, Ömer Faruk, Penzel, Nora, Rangnick, Adrian, von Saldern, Sebastian, Spangemacher, Moritz, Tupac, Ana, Urquijo, Maria Fernanda, Weiske, Johanna, Wenzel, Julian, Wosgien, Antonia, Betz, Linda, Blume, Karsten, Kaiser, Nathalie, Lichtenstein, Thorsten, Woopen, Christiane, Andreou, Christina, Egloff, Laura, Harrisberger, Fabienne, Lenz, Claudia, Leanza, Letizia, Mackintosh, Amatya, Smieskova, Renata, Studerus, Erich, Walter, Anna, Widmayer, Sonja, Day, Chris, Griffiths, Sian Lowri, Iqbal, Mariam, Mallikarjun, Pavan, Stainton, Alexandra, Lin, Ashleigh, Heinimaa, Markus, Ilonen, Tuula, Jalo, Päivi, Laurikainen, Heikki, Lehtinen, Maarit, Luutonen, Antti, Mäkela, Akseli, Paju, Janina, Pesonen, Henri, Sormunen, Elina, Toivonen, Anna, Turtonen, Otto, Solana, Ana Beatriz, Abraham, Manuela, Hehn, Nicolas, Schirmer, Timo, Altamura, Carlo, Belleri, Marika, Bottinelli, Francesca, Ferro, Adele, Re, Marta, Percudani, Mauro, Sberna, Maurizio, D’Agostino, Armando, Del Fabro, Lorenzo, Perna, Giampaolo, Alciati, Alessandra, Balestrieri, Matteo, Bonivento, Carolina, Cabras, Giuseppe, Garzitto, Marco, Piccin, Sara

Volltext

Target-specific, histology-independent, randomized discontinuation study of lapatinib in patients with HER2-amplified solid tumors von Galsky, Matthew D., Von Hoff, Daniel D., Neubauer, Marcus, Anderson, Thomas, Fleming, Mark, Nagarwala, Yasir, Mahoney, Janine M., Midwinter, Dawn, Vocila, Linda, Zaks, Tal Z.

Volltext

Using combined environmental–clinical classification models to predict role functioning outcome in clinical high-risk states for psychosis and recent-onset depression von Antonucci, Linda A., Penzel, Nora, Sanfelici, Rachele, Pigoni, Alessandro, Kambeitz-Ilankovic, Lana, Dwyer, Dominic, Ruef, Anne, Sen Dong, Mark, Öztürk, Ömer Faruk, Chisholm, Katharine, Haidl, Theresa, Rosen, Marlene, Ferro, Adele, Pergola, Giulio, Andriola, Ileana, Blasi, Giuseppe, Ruhrmann, Stephan, Schultze-Lutter, Frauke, Falkai, Peter, Kambeitz, Joseph, Lencer, Rebekka, Dannlowski, Udo, Upthegrove, Rachel, Salokangas, Raimo K. R., Pantelis, Christos, Meisenzahl, Eva, Wood, Stephen J., Brambilla, Paolo, Borgwardt, Stefan, Bertolino, Alessandro, Koutsouleris, Nikolaos

Volltext

Validation of the Bullying Scale for Adults - Results of the PRONIA-study von Haidl, Theresa Katharina, Schneider, Nicole, Dickmann, Kim, Ruhrmann, Stephan, Kaiser, Nathalie, Rosen, Marlene, Seves, Mauro, Lichtenstein, Thorsten, Upthegrove, Rachel, Salokangas, Raimo K.R., Pantelis, Christos, Meisenzahl, Eva, Wood, Stephen J., Brambilla, Paolo, Borgwardt, Stefan, Rebekka, Lencer, Kambeitz, Joseph, Koutsouleris, Nikolaos, Schultze-Lutter, Frauke, Betz, Linda, Erkens, Anne, Gussmann, Eva, Haas, Shalaila, Hasan, Alkomiet, Hoff, Claudius, Khanya-ree, Ifrah, Melo, Aylin, Muckenhuber-Sternbauer, Susanna, Köhler, Janis, Öztürk, Ömer, Penzel, Nora, Popovic, David, Rangnick, Adrian, von Saldern, Sebastian, Sanfelici, Rachele, Spangemacher, Moritz, Tupac, Ana, Urquijo, Maria Fernanda, Weiske, Johanna, Wosgien, Antonia, Hedderich, Dennis, Blume, Karsten, Woopen, Christiane, Andreou, Christina, Egloff, Laura, Harrisberger, Fabienne, Lenz, Claudia, Leanza, Letizia, Mackin-tosh, Amatya, Smieskova, Renata, Studerus, Erich, Walter, Anna, Widmayer, Sonja, Day, Chris, Griffiths, Sian Lowri, Iqbal, Mariam, Pelton, Mirabel, Mallikarjun, Pavan, Stainton, Alexandra, Lin, Ashleigh, Denissoff, Alexander, Ellilä, Anu, From, Tiina, Heinimaa, Markus, Ilonen, Tuula, Jalo, Päivi, Lauri-kainen, Heikki, Luutonen, Antti, Mäkela, Akseli, Paju, Janina, Pesonen, Henri, Armio, Reetta-Liina, Toivonen, Anna, Turtonen, Otto, Solana, Ana Beatriz, Abraham, Manuela, Hehn, Nicolas, Schirmer, Timo, Altamura, Carlo, Belleri, Marika, Bottinelli, Francesca, Ferro, Adele, Re, Marta, Monzani, Emiliano, Percudani, Mauro, Sberna, Maurizio, D'Agostino, Armando, Del Fabro, Lorenzo, Perna, Giampaolo, Nobile, Maria, Alciati, Alessandra, Balestrieri, Matteo, Bonivento, Carolina, Cabras, Giuseppe, Fabbro, Franco, Garzitto, Marco, Piccin, Sara

Volltext

Alterations of Functional Connectivity Dynamics in Affective and Psychotic Disorders von Hoheisel, Linnea, Kambeitz-Ilankovic, Lana, Wenzel, Julian, Haas, Shalaila S., Antonucci, Linda A., Ruef, Anne, Penzel, Nora, Schultze-Lutter, Frauke, Lichtenstein, Theresa, Rosen, Marlene, Dwyer, Dominic B., Lencer, Rebekka, Brambilla, Paolo, Borgwardt, Stephan, Wood, Stephen J., Upthegrove, Rachel, Bertolino, Alessandro, Ruhrmann, Stephan, Meisenzahl, Eva, Koutsouleris, Nikolaos, Fink, Gereon R., Daun, Silvia, Kambeitz, Joseph, Betz, Linda, Erkens, Anne, Gussmann, Eva, Haas, Shalaila, Hasan, Alkomiet, Khanyaree, Ifrah, Melo, Aylin, Muckenhuber-Sternbauer, Susanna, Köhler, Janis, Öztürk, Ömer, Penzel, Nora, Popovic, David, Rangnick, Adrian, von Saldern, Sebastian, Sanfelici, Rachele, Spangemacher, Moritz, Tupac, Ana, Urquijo, Maria Fernanda, Weiske, Johanna, Wosgien, Antonia, Blume, Karsten, Gebhardt, Dominika, Kaiser, Nathalie, Milz, Ruth, Seves, Mauro, Vent, Silke, Wassen, Martina, Andreou, Christina, Egloff, Laura, Harrisberger, Fabienne, Lenz, Claudia, Leanza, Letizia, Mackintosh, Amatya, Smieskova, Renata, Studerus, Erich, Widmayer, Sonja, Day, Chris, Iqbal, Mariam, Pelton, Mirabel, Mallikarjun, Pavan, Stainton, Alexandra, Lin, Ashleigh, Denissoff, Alexander, Ellilä, Anu, From, Tiina, Heinimaa, Markus, Ilonen, Tuula, Jalo, Päivi, Laurikainen, Heikki, Luutonen, Antti, Mäkela, Akseli, Paju, Janina, Pesonen, Henri, Toivonen, Anna, Turtonen, Otto, Solana, Ana Beatriz, Abraham, Manuela, Hehn, Nicolas, Schirmer, Timo, Altamura, Carlo, Belleri, Marika, Bottinelli, Francesca, Ferro, Adele, Re, Marta, Monzani, Emiliano, Sberna, Maurizio, D’Agostino, Armando, Del Fabro, Lorenzo, Perna, Giampaolo, Nobile, Maria, Alciati, Alessandra, Balestrieri, Matteo, Bonivento, Carolina, Cabras, Giuseppe, Fabbro, Franco, Garzitto, Marco, Piccin, Sara

Volltext

Phase I clinical and pharmacologic study of eniluracil plus fluorouracil in patients with advanced cancer von SCHILSKY, R. L, HOHNEKER, J, RATAIN, M. J, JANISCH, L, SMETZER, L, SOL LUCAS, V, SOO PEONG KHOR, DIASIO, R, VON HOFF, D. D, BURRIS, H. A

Volltext

Target-specific randomized discontinuation trial design: a novel approach in molecular therapeutics von Galsky, Matthew D., Zaks, Tal, Hassani, Habib, Vocila, Linda, Sonpavde, Guru, Hutson, Thomas E., Von Hoff, Daniel D.

Volltext

Phase I trial of intravenous IL-4 Pseudomonas exotoxin protein (NBI-3001) in patients with advanced solid tumors that express the IL-4 receptor von GARLAND, Linda, GITLITZ, Barbara, EBBINGHAUS, Scot, PAN, Henry, DE HAAN, Hans, PURI, Raj K, VON HOFF, Daniel, FIGLIN, Robert

Volltext

Inferior quantitative and qualitative immune responses to pneumococcal conjugate vaccine in infants with nasopharyngeal colonization by Streptococcus pneumoniae during the primary... von Madhi, Shabir A, Violari, Avy, Klugman, Keith P, Lin, Gina, McIntyre, James A, von Gottberg, Anne, Jean-Philippe, Patrick, Cotton, Mark F, Adrian, Peter

Volltext

Phase I and pharmacokinetic study of GI147211, a water-soluble camptothecin analogue, administered for five consecutive days every three weeks von ECKHARDT, S. G, BAKER, S. D, ROTHENBERG, M. L, WHITE, L, WISSEL, P, KUNKA, R, DEPEE, S, LITTLEFIELD, D, BURRIS, H. A, VON HOFF, D. D, ROWINSKY, E. K, ECKARDT, J. R, BURKE, T. G, WARNER, D. L, KUHN, J. G, RODRIGUEZ, G, FIELDS, S, THURMAN, A, SMITH, L

Volltext

O-287 Phase 2 study of TLK286 (GST P1-1 activated glutathione analog) administered weekly in patients with platinum refractory of resistant non-small cell lung cancer (NSCLC) von Papadimitrakopoulou, Vassiliki, Blumenschein, George, Fossella, Frank, Figlin, Robert, Gilitz, Barbara, Garland, Linda, Von Hoff, Daniel, King, Lisa, Jameson, Anneliese, Brown, Gail L.

Volltext