Effect of bradykinin metabolism inhibitors on evoked hypotension in rats: rank efficacy of enzymes associated with bradykinin‐mediated angioedema von Fryer, R M, Segreti, J, Banfor, P N, Widomski, D L, Backes, B J, Lin, C W, Ballaron, S J, Cox, B F, Trevillyan, J M, Reinhart, G A, Geldern, T W

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Novel p-Arylthio Cinnamides as Antagonists of Leukocyte Function-Associated Antigen-1/Intracellular Adhesion Molecule-1 Interaction. 2. Mechanism of Inhibition and Structure-Based... von Liu, Gang, Huth, Jeffrey R, Olejniczak, Edward T, Mendoza, Renaldo, DeVries, Peter, Leitza, Sandra, Reilly, Edward B, Okasinski, Gregory F, Fesik, Stephen W, von Geldern, Thomas W

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Discovery of Novel p-Arylthio Cinnamides as Antagonists of Leukocyte Function-Associated Antigen-1/Intracellular Adhesion Molecule-1 Interaction. 1. Identification of an Additional... von Liu, Gang, Link, J. T, Pei, Zhonghua, Reilly, Edward B, Leitza, Sandra, Nguyen, Bach, Marsh, Kennan C, Okasinski, Gregory F, von Geldern, Thomas W, Ormes, Mark, Fowler, Kerry, Gallatin, Mike

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Discovery of Novel p-Arylthio Cinnamides as Antagonists of Leukocyte Function-Associated Antigen-1/Intercellular Adhesion Molecule-1 Interaction. 4. Structure−Activity Relationship... von Winn, Martin, Reilly, Edward B, Liu, Gang, Huth, Jeffrey R, Jae, Hwan-Soo, Freeman, Jennifer, Pei, Zhonghua, Xin, Zhili, Lynch, John, Kester, Jeff, von Geldern, Thomas W, Leitza, Sandra, DeVries, Peter, Dickinson, Robert, Mussatto, Donna, Okasinski, Gregory F

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Discovery of Potent Antagonists of Leukocyte Function-Associated Antigen-1/Intercellular Adhesion Molecule-1 Interaction. 3. Amide (C-Ring) Structure−Activity Relationship and Impr... von Pei, Zhonghua, Xin, Zhili, Liu, Gang, Li, Yihong, Reilly, Edward B, Lubbers, Nathan L, Huth, Jeffery R, Link, James T, von Geldern, Thomas W, Cox, Bryan F, Leitza, Sandra, Gao, Yi, Marsh, Kennan C, DeVries, Peter, Okasinski, Greg F

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Pyrrolidine-3-carboxylic Acids as Endothelin Antagonists. 3. Discovery of a Potent, 2-Nonaryl, Highly Selective ETA Antagonist (A-216546) von Liu, Gang, Henry, Kenneth J, Szczepankiewicz, Bruce G, Winn, Martin, Kozmina, Natasha S, Boyd, Steven A, Wasicak, James, von Geldern, Thomas W, Wu-Wong, Jinshyun R, Chiou, William J, Dixon, Douglas B, Nguyen, Bach, Marsh, Kennan C, Opgenorth, Terry J

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Pyrrolidine-3-carboxylic Acids as Endothelin Antagonists. 4. Side Chain Conformational Restriction Leads to ETB Selectivity von von Geldern, Thomas W, Tasker, Andrew S, Sorensen, Bryan K, Winn, Martin, Szczepankiewicz, Bruce G, Dixon, Douglas B, Chiou, William J, Wang, Liming, Wessale, Jerry L, Adler, Andy, Marsh, Kennan C, Nguyen, Bach, Opgenorth, Terry J

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Atrial natriuretic peptide and glomerular hyperfiltration during onset of spontaneous diabetes mellitus von Okwueze, M. I, Opgenorth, T. J, von Geldern, T. W, Vari, R. C

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Pyrrolidine-3-carboxylic Acids as Endothelin Antagonists. 2. Sulfonamide-Based ETA/ETB Mixed Antagonists von Jae, Hwan-Soo, Winn, Martin, Dixon, Douglas B, Marsh, Kennan C, Nguyen, Bach, Opgenorth, Terry J, von Geldern, Thomas W

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Design, Synthesis, and Activity of a Series of Pyrrolidine-3-carboxylic Acid-Based, Highly Specific, Orally Active ETB Antagonists Containing a Diphenylmethylamine Acetamide Side C... von Liu, Gang, Kozmina, Natasha S, Winn, Martin, von Geldern, Thomas W, Chiou, William J, Dixon, Douglas B, Nguyen, Bach, Marsh, Kennan C, Opgenorth, Terry J

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Azole Endothelin Antagonists. 3. Using Δ log P as a Tool To Improve Absorption von von Geldern, Thomas W, Hoffman, Daniel J, Kester, Jeffrey A, Nellans, Hugh N, Dayton, Brian D, Calzadilla, Samuel V, Marsh, Kennan C, Hernandez, Lisa, Chiou, William, Dixon, Douglas B, Wu-Wong, Jinshyun R, Opgenorth, Terry J

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Discovery of a series of pyrrolidine-based endothelin receptor antagonists with enhanced ETA receptor selectivity von BOYD, S. A, MANTEI, R. A, DIXON, D. B, HUTCHINS, C. W, MARSH, K. C, NGUYEN, B, OPGENORTH, T. J, TASKER, A. S, GANG LIU, SORENSEN, B. K, HENRY, K. J, VON GELDERN, T. W, WINN, M, WU-WONG, J. R, CHIOU, W. J

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Pharmacology of A-216546 : a highly selective antagonist for endothelin ETA receptor von WU-WONG, J. R, DIXON, D. B, GANG LIU, SZCZEPANKIEWICZ, B, VON GELDERN, T. W, OPGENORTH, T. J, CHIOU, W. J, DAYTON, B. D, NOVOSAD, E. I, ADLER, A. L, WESSALE, J. L, CALZADILLA, S. V, HERNANDEZ, L, MARSH, K. C

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Benzoxazole benzenesulfonamides are novel allosteric inhibitors of fructose-1,6-bisphosphatase with a distinct binding mode von von Geldern, Thomas W., Lai, Chunqiu, Gum, Rebecca J., Daly, Melissa, Sun, Chaohong, Fry, Elizabeth H., Abad-Zapatero, Celerino

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Pyrrolidine-3-carboxylic acids as endothelin antagonists. 4. Side chain conformational restriction leads to ET(B) selectivity von von Geldern, T W, Tasker, A S, Sorensen, B K, Winn, M, Szczepankiewicz, B G, Dixon, D B, Chiou, W J, Wang, L, Wessale, J L, Adler, A, Marsh, K C, Nguyen, B, Opgenorth, T J

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New Antimitotic Agents with Activity in Multi-Drug-Resistant Cell Lines and in Vivo Efficacy in Murine Tumor Models von Szczepankiewicz, Bruce G, Liu, Gang, Jae, Hwan-Soo, Tasker, Andrew S, Gunawardana, Indrani W, von Geldern, Thomas W, Gwaltney, Stephen L, Wu-Wong, J. Ruth, Gehrke, Laura, Chiou, William J, Credo, R. Bruce, Alder, Jeffery D, Nukkala, Michael A, Zielinski, Nicolette A, Jarvis, Ken, Mollison, Karl W, Frost, David J, Bauch, Joy L, Hui, Yu Hua, Claiborne, Akiyo K, Li, Qun, Rosenberg, Saul H

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The effects of diminishing albumin binding to some Endothelin receptor antagonists von Szczepankiewicz, Bruce G., Bal, Radhika B., von Geldern, Thomas W., Wu-Wong, Jinshyun R., Chiou, William J., Dixon, Douglas B., Opgenorth, Terry J., Hoffman, Daniel J., Borre, Anthony J., Marsh, Kennan C., Nguyen, Bach N.

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A ring-reversed analog of atrial natriuretic peptide retains receptor binding, guanylate cyclase stimulation von von Geldern, Thomas W., Budzik, Gerald P., Dillon, Terry P.

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Azole Endothelin Antagonists. 2. Structure−Activity Studies von von Geldern, Thomas W, Kester, Jeffrey A, Bal, Radhika, Wu-Wong, Jinshyun R, Chiou, William, Dixon, Douglas B, Opgenorth, Terry J

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Potent and Selective Non-Benzodioxole-Containing Endothelin-A Receptor Antagonists von Tasker, Andrew S, Sorensen, Bryan K, Jae, Hwan-Soo, Winn, Martin, von Geldern, Thomas W, Dixon, Douglas B, Chiou, William J, Dayton, Brian D, Calzadila, Samuel, Hernandez, Lisa, Marsh, Kennan C, WuWong, J. Ruth, Opgenorth, Terry J

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