The effect of APOE and other common genetic variants on the onset of Alzheimer's disease and dementia: a community-based cohort study von van der Lee, Sven J, Wolters, Frank J, Ikram, M Kamran, Hofman, Albert, Ikram, M Arfan, Amin, Najaf, van Duijn, Cornelia M

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The coarse-grained plaque: a divergent Aβ plaque-type in early-onset Alzheimer’s disease von Boon, Baayla D. C., Bulk, Marjolein, Jonker, Allert J., Morrema, Tjado H. J., van den Berg, Emma, Popovic, Marko, Walter, Jochen, Kumar, Sathish, van der Lee, Sven J., Holstege, Henne, Zhu, Xiaoyue, Van Nostrand, William E., Natté, Remco, van der Weerd, Louise, Bouwman, Femke H., van de Berg, Wilma D. J., Rozemuller, Annemieke J. M., Hoozemans, Jeroen J. M.

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Genome-wide association study of frontotemporal dementia identifies a C9ORF72 haplotype with a median of 12-G4C2 repeats that predisposes to pathological repeat expansions von Reus, Lianne M., Jansen, Iris E., Mol, Merel O., van Ruissen, Fred, van Rooij, Jeroen, van Schoor, Natasja M., Tesi, Niccolò, Reinders, Marcel J. T., Huisman, Martijn A., Holstege, Henne, Visser, Pieter Jelle, de Boer, Sterre C. M., Hulsman, Marc, Ahmad, Shahzad, Amin, Najaf, Uitterlinden, Andre G., Ikram, Arfan, van Duijn, Cornelia M., Seelaar, Harro, Ramakers, Inez H. G. B., Verhey, Frans R. J., van der Lugt, Aad, Claassen, Jurgen A. H. R., Jan Biessels, Geert, De Deyn, Peter Paul, Scheltens, Philip, van der Flier, Wiesje M., van Swieten, John C., Pijnenburg, Yolande A. L., van der Lee, Sven J.

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A meta-analysis of genome-wide association studies identifies multiple longevity genes von Deelen, Joris, Evans, Daniel S., Arking, Dan E., Tesi, Niccolò, Nygaard, Marianne, Liu, Xiaomin, Wojczynski, Mary K., Biggs, Mary L., van der Spek, Ashley, Atzmon, Gil, Ware, Erin B., Sarnowski, Chloé, Smith, Albert V., Seppälä, Ilkka, Cordell, Heather J., Dose, Janina, Amin, Najaf, Arnold, Alice M., Ayers, Kristin L., Barzilai, Nir, Becker, Elizabeth J., Beekman, Marian, Blanché, Hélène, Christensen, Kaare, Christiansen, Lene, Collerton, Joanna C., Cubaynes, Sarah, Cummings, Steven R., Davies, Karen, Debrabant, Birgit, Deleuze, Jean-François, Duncan, Rachel, Faul, Jessica D., Franceschi, Claudio, Galan, Pilar, Gudnason, Vilmundur, Harris, Tamara B., Huisman, Martijn, Hurme, Mikko A., Jagger, Carol, Jansen, Iris, Jylhä, Marja, Kähönen, Mika, Karasik, David, Kardia, Sharon L. R., Kingston, Andrew, Kirkwood, Thomas B. L., Launer, Lenore J., Lehtimäki, Terho, Lieb, Wolfgang, Lyytikäinen, Leo-Pekka, Martin-Ruiz, Carmen, Min, Junxia, Nebel, Almut, Newman, Anne B., Nie, Chao, Nohr, Ellen A., Orwoll, Eric S., Perls, Thomas T., Province, Michael A., Psaty, Bruce M., Raitakari, Olli T., Reinders, Marcel J. T., Robine, Jean-Marie, Rotter, Jerome I., Sebastiani, Paola, Smith, Jennifer, Sørensen, Thorkild I. A., Taylor, Kent D., Uitterlinden, André G., van der Flier, Wiesje, van der Lee, Sven J., van Duijn, Cornelia M., van Heemst, Diana, Vaupel, James W., Weir, David, Ye, Kenny, Zeng, Yi, Zheng, Wanlin, Holstege, Henne, Kiel, Douglas P., Lunetta, Kathryn L., Slagboom, P. Eline, Murabito, Joanne M.

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Alzheimer's disease genetic pathways impact cerebrospinal fluid biomarkers and imaging endophenotypes in non‐demented individuals von Lorenzini, Luigi, Collij, Lyduine E., Tesi, Niccoló, Vilor‐Tejedor, Natàlia, Ingala, Silvia, Blennow, Kaj, Foley, Christopher, Frisoni, Giovanni B., Haller, Sven, Holstege, Henne, van der Lee, Sven, Martinez‐Lage, Pablo, Marioni, Riccardo E., McCartney, Daniel L., O’ Brien, John, Oliveira, Tiago Gil, Payoux, Pierre, Reinders, Marcel, Ritchie, Craig, Scheltens, Philip, Schwarz, Adam J., Sudre, Carole H., Waldman, Adam D., Wolz, Robin, Chatelat, Gael, Ewers, Michael, Wink, Alle Meije, Mutsaerts, Henk J. M. M., Gispert, Juan Domingo, Visser, Pieter Jelle, Tijms, Betty M., Altmann, Andre, Barkhof, Frederik

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The association of vascular disorders with incident dementia in different age groups von Legdeur, Nienke, van der Lee, Sven J, de Wilde, Marcel, van der Lei, Johan, Muller, Majon, Maier, Andrea B, Visser, Pieter Jelle

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PLCG2 protective variant p.P522R modulates tau pathology and disease progression in patients with mild cognitive impairment von Kleineidam, Luca, Chouraki, Vincent, Próchnicki, Tomasz, van der Lee, Sven J., Madrid-Márquez, Laura, Wagner-Thelen, Holger, Karaca, Ilker, Weinhold, Leonie, Wolfsgruber, Steffen, Boland, Anne, Martino Adami, Pamela V., Lewczuk, Piotr, Popp, Julius, Brosseron, Frederic, Jansen, Iris E., Hulsman, Marc, Kornhuber, Johannes, Peters, Oliver, Berr, Claudine, Heun, Reinhard, Frölich, Lutz, Tzourio, Christophe, Dartigues, Jean-François, Hüll, Michael, Espinosa, Ana, Hernández, Isabel, de Rojas, Itziar, Orellana, Adelina, Valero, Sergi, Stringa, Najada, van Schoor, Natasja M., Huisman, Martijn, Scheltens, Philip, Rüther, Eckart, Deleuze, Jean-Francois, Wiltfang, Jens, Tarraga, Lluis, Schmid, Matthias, Scherer, Martin, Riedel-Heller, Steffi, Heneka, Michael T., Amouyel, Philippe, Jessen, Frank, Boada, Merce, Maier, Wolfgang, Schneider, Anja, González-Pérez, Antonio, van der Flier, Wiesje M., Wagner, Michael, Lambert, Jean-Charles, Holstege, Henne, Sáez, Mª Eugenia, Latz, Eicke, Ruiz, Agustin, Ramirez, Alfredo

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Centenarian controls increase variant effect sizes by an average twofold in an extreme case-extreme control analysis of Alzheimer's disease von Tesi, Niccolò, van der Lee, Sven J, Hulsman, Marc, Jansen, Iris E, Stringa, Najada, van Schoor, Natasja, Meijers-Heijboer, Hanne, Huisman, Martijn, Scheltens, Philip, Reinders, Marcel J T, van der Flier, Wiesje M, Holstege, Henne

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SORL1 deficiency in human excitatory neurons causes APP-dependent defects in the endolysosome-autophagy network von Hung, Christy, Tuck, Eleanor, Stubbs, Victoria, van der Lee, Sven J, Aalfs, Cora, van Spaendonk, Resie, Scheltens, Philip, Hardy, John, Holstege, Henne, Livesey, Frederick J

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Alzheimer's disease genetic pathways impact cerebrospinal fluid biomarkers and imaging endophenotypes in non‐demented individuals von Lorenzini, Luigi, Collij, Lyduine, Tesi, Niccoló, Vilor-Tejedor, Natàlia, Ingala, Silvia, Blennow, Kaj, Foley, Christopher, Frisoni, Giovanni, Haller, Sven, Holstege, Henne, van der van der Lee, Sven, Martinez-Lage, Pablo, Marioni, Riccardo, Mccartney, Daniel, O’ Brien, John, Oliveira, Tiago Gil, Payoux, Pierre, Reinders, Marcel, Ritchie, Craig, Scheltens, Philip, Schwarz, Adam, Sudre, Carole, Waldman, Adam, Wolz, Robin, Chatelat, Gael, Ewers, Michael, Wink, Alle Meije, Mutsaerts, Henk, Gispert, Juan Domingo, Visser, Pieter Jelle, Tijms, Betty, Altmann, Andre, Barkhof, Frederik

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The global impact of non-communicable diseases on healthcare spending and national income: a systematic review von Muka, Taulant, Imo, David, Jaspers, Loes, Colpani, Veronica, Chaker, Layal, van der Lee, Sven J., Mendis, Shanthi, Chowdhury, Rajiv, Bramer, Wichor M., Falla, Abby, Pazoki, Raha, Franco, Oscar H.

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Interest in genetic susceptibility testing and disclosure of AD dementia risk in cognitively normal adults: a survey study von Waterink, Lisa, Masselink, Larissa A, van der Lee, Sven J, Visser, Leonie N C, Cleutjens, Solange, van der Schaar, Jetske, van Harten, Argonde C, Scheltens, Philip, Sikkes, Sietske A M, van der Flier, Wiesje M, Zwan, Marissa D

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Fine-mapping the effects of Alzheimer’s disease risk loci on brain morphology von Roshchupkin, G.V, Adams, H.H.H, van der Lee, S.J, Vernooij, M.W, van Duijn, C.M, Uitterlinden, A.G, van der Lugt, A, Hofman, A, Niessen, W.J, Ikram, M.A

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The global impact of non-communicable diseases on households and impoverishment: a systematic review von Jaspers, Loes, Colpani, Veronica, Chaker, Layal, van der Lee, Sven J., Muka, Taulant, Imo, David, Mendis, Shanthi, Chowdhury, Rajiv, Bramer, Wichor M., Falla, Abby, Pazoki, Raha, Franco, Oscar H.

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Heritability of the shape of subcortical brain structures in the general population von Roshchupkin, Gennady V., Gutman, Boris A., Vernooij, Meike W., Jahanshad, Neda, Martin, Nicholas G., Hofman, Albert, McMahon, Katie L., van der Lee, Sven J., van Duijn, Cornelia M., de Zubicaray, Greig I., Uitterlinden, André G., Wright, Margaret J., Niessen, Wiro J., Thompson, Paul M., Ikram, M. Arfan, Adams, Hieab H. H.

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A genome-wide association study identifies genetic loci associated with specific lobar brain volumes von van der Lee, Sven J., Knol, Maria J., Chauhan, Ganesh, Satizabal, Claudia L., Smith, Albert Vernon, Hofer, Edith, Bis, Joshua C., Hibar, Derrek P., Hilal, Saima, van den Akker, Erik B., Arfanakis, Konstantinos, Bernard, Manon, Yanek, Lisa R., Amin, Najaf, Crivello, Fabrice, Cheung, Josh W., Harris, Tamara B., Saba, Yasaman, Lopez, Oscar L., Li, Shuo, van der Grond, Jeroen, Yu, Lei, Paus, Tomas, Roshchupkin, Gennady V., Amouyel, Philippe, Jahanshad, Neda, Taylor, Kent D., Yang, Qiong, Mathias, Rasika A., Boehringer, Stefan, Mazoyer, Bernard, Rice, Ken, Cheng, Ching Yu, Maillard, Pauline, van Heemst, Diana, Wong, Tien Yin, Niessen, Wiro J., Beiser, Alexa S., Beekman, Marian, Zhao, Wanting, Nyquist, Paul A., Chen, Christopher, Launer, Lenore J., Psaty, Bruce M., Ikram, M. Kamran, Vernooij, Meike W., Schmidt, Helena, Pausova, Zdenka, Becker, Diane M., De Jager, Philip L., Thompson, Paul M., van Duijn, Cornelia M., Bennett, David A., Slagboom, P. Eline, Schmidt, Reinhold, Longstreth, W. T., Ikram, M. Arfan, Seshadri, Sudha, Debette, Stéphanie, Gudnason, Vilmundur, Adams, Hieab H. H., DeCarli, Charles

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Cerebrospinal fluid tau levels are associated with abnormal neuronal plasticity markers in Alzheimer's disease von Visser, Pieter Jelle, Reus, Lianne M, Gobom, Johan, Jansen, Iris, Dicks, Ellen, van der Lee, Sven J, Tsolaki, Magda, Verhey, Frans R J, Popp, Julius, Martinez-Lage, Pablo, Vandenberghe, Rik, Lleó, Alberto, Molinuevo, José Luís, Engelborghs, Sebastiaan, Freund-Levi, Yvonne, Froelich, Lutz, Sleegers, Kristel, Dobricic, Valerija, Lovestone, Simon, Streffer, Johannes, Vos, Stephanie J B, Bos, Isabelle, Smit, August B, Blennow, Kaj, Scheltens, Philip, Teunissen, Charlotte E, Bertram, Lars, Zetterberg, Henrik, Tijms, Betty M

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Male-specific epistasis between WWC1 and TLN2 genes is associated with Alzheimer's disease von Gusareva, Elena S., Twizere, Jean-Claude, Sleegers, Kristel, Dourlen, Pierre, Abisambra, Jose F., Meier, Shelby, Cloyd, Ryan, Weiss, Blaine, Dermaut, Bart, Bessonov, Kyrylo, van der Lee, Sven J., Carrasquillo, Minerva M., Katsumata, Yuriko, Cherkaoui, Majid, Asselbergh, Bob, Ikram, M. Arfan, Mayeux, Richard, Farrer, Lindsay A., Haines, Jonathan L., Pericak-Vance, Margaret A., Schellenberg, Gerard D., Sims, Rebecca, Williams, Julie, Amouyel, Philippe, van Duijn, Cornelia M., Ertekin-Taner, Nilüfer, Van Broeckhoven, Christine, Dequiedt, Franck, Fardo, David W., Lambert, Jean-Charles, Van Steen, Kristel

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The global impact of non-communicable diseases on macro-economic productivity: a systematic review von Chaker, Layal, Falla, Abby, van der Lee, Sven J., Muka, Taulant, Imo, David, Jaspers, Loes, Colpani, Veronica, Mendis, Shanthi, Chowdhury, Rajiv, Bramer, Wichor M., Pazoki, Raha, Franco, Oscar H.

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Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease von Desikan, Rahul S, Schork, Andrew J, Wang, Yunpeng, Thompson, Wesley K, Dehghan, Abbas, Ridker, Paul M, Chasman, Daniel I, McEvoy, Linda K, Holland, Dominic, Chen, Chi-Hua, Karow, David S, Brewer, James B, Hess, Christopher P, Williams, Julie, Sims, Rebecca, O'Donovan, Michael C, Choi, Seung Hoan, Bis, Joshua C, Ikram, M Arfan, Gudnason, Vilmundur, DeStefano, Anita L, van der Lee, Sven J, Psaty, Bruce M, van Duijn, Cornelia M, Launer, Lenore, Seshadri, Sudha, Pericak-Vance, Margaret A, Mayeux, Richard, Haines, Jonathan L, Farrer, Lindsay A, Hardy, John, Ulstein, Ingun Dina, Aarsland, Dag, Fladby, Tormod, White, Linda R, Sando, Sigrid B, Rongve, Arvid, Witoelar, Aree, Djurovic, Srdjan, Hyman, Bradley T, Snaedal, Jon, Steinberg, Stacy, Stefansson, Hreinn, Stefansson, Kari, Schellenberg, Gerard D, Andreassen, Ole A, Dale, Anders M

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