Preclinical Strategies to Identify Off-Target Toxicity of High-Affinity TCRs von Bijen, Helena M., van der Steen, Dirk M., Hagedoorn, Renate S., Wouters, Anne K., Wooldridge, Linda, Falkenburg, J.H. Frederik, Heemskerk, Mirjam H.M.

Volltext

A library of cancer testis specific T cell receptors for T cell receptor gene therapy von de Rooij, Marije A.J., Remst, Dennis F.G., van der Steen, Dirk M., Wouters, Anne K., Hagedoorn, Renate S., Kester, Michel G.D., Meeuwsen, Miranda H., Wachsmann, Tassilo L.A., de Ru, Arnoud H., van Veelen, Peter A., Verdegaal, Els M.E., Falkenburg, J.H. Frederik, Heemskerk, Mirjam H.M.

Volltext

Combined CD8+ and CD4+ adenovirus hexon-specific T cells associated with viral clearance after stem cell transplantation as treatment for adenovirus infection von ZANDVLIET, Maarten L, FREDERIK FALKENBURG, J. H, GUCHELAAR, Henk-Jan, SCHILHAM, Marco W, MEIJ, Pauline, VAN LIEMPT, Ellis, VELTROP-DUITS, Louise A, LANKESTER, Arjan C, KALPOE, Jayant S, KESTER, Michel G. D, VAN DER STEEN, Dirk M, VAN TOL, Maarten J, WILLEMZE, Roel

Volltext

PRAME as a Potential Target for Immunotherapy in Metastatic Uveal Melanoma von Gezgin, Gülçin, Luk, Sietse J, Cao, Jinfeng, Dogrusöz, Mehmet, van der Steen, Dirk M, Hagedoorn, Renate S, Krijgsman, Daniëlle, van der Velden, Pieter A, Field, Matthew G, Luyten, Gregorius P. M, Szuhai, Karoly, Harbour, J. William, Jordanova, Ekaterina S, Heemskerk, Mirjam H. M, Jager, Martine J

Volltext

A broad and systematic approach to identify B cell malignancy-targeting TCRs for multi-antigen-based T cell therapy von Meeuwsen, Miranda H., Wouters, Anne K., Jahn, Lorenz, Hagedoorn, Renate S., Kester, Michel G.D., Remst, Dennis F.G., Morton, Laura T., van der Steen, Dirk M., Kweekel, Christiaan, de Ru, Arnoud H., Griffioen, Marieke, van Veelen, Peter A., Falkenburg, J.H. Frederik, Heemskerk, Mirjam H.M.

Volltext

PRAME-Specific Allo-HLA―Restricted T Cells with Potent Antitumor Reactivity Useful for Therapeutic T-Cell Receptor Gene Transfer von AMIR, Avital L, VAN DER STEEN, Dirk M, JEDEMA, Inge, GRIFFIOEN, Marieke, VAN VEELEN, Peter A, FALKENBURG, J. H. Frederik, HEEMSKERK, Mirjam H. M, VAN LOENEN, Marleen M, HAGEDOORN, Renate S, DE BOER, Renate, KESTER, Michel D. G, DE RU, Arnoud H, LUGTHART, Gert-Jan, VAN KOOTEN, Cees, HIEMSTRA, Pieter S

Volltext

Identification of Varicella-Zoster Virus-Specific CD8 T Cells in Patients after T-Cell-Depleted Allogeneic Stem Cell Transplantation von VAN DER HEIDEN, Pim L. J, DE BOER, Renate, WILLEMZE, Roel, FALKENBURG, J. H. Frederik, HEEMSKERK, Mirjam H. M, VAN DER STEEN, Dirk M, KESTER, Michel G. D, VAN DER HOORN, Menno W. A. G, HAARMAN, Wilmy M. E, BARNBY-PORRITT, Helen E, FRY, Jeremy W, NAPPER, C. E, MARIJT, Erik W. A

Volltext

Allo-HLA–reactive T cells inducing graft-versus-host disease are single peptide specific von Amir, Avital L., van der Steen, Dirk M., Hagedoorn, Renate S., Kester, Michel G.D., van Bergen, Cornelis A.M., Drijfhout, Jan W., de Ru, Arnoud H., Falkenburg, J. H. Frederik, van Veelen, Peter A., Heemskerk, Mirjam H.M.

Volltext

A CD22-reactive TCR from the T-cell allorepertoire for the treatment of acute lymphoblastic leukemia by TCR gene transfer von Jahn, Lorenz, Hagedoorn, Renate S, van der Steen, Dirk M, Hombrink, Pleun, Kester, Michel G D, Schoonakker, Marjolein P, de Ridder, Daniëlle, van Veelen, Peter A, Falkenburg, J H Frederik, Heemskerk, Mirjam H M

Volltext

A library of cancer testis specific T cell receptors for T cell receptor gene therapy von de Rooij, Marije A.J., Remst, Dennis F.G., van der Steen, Dirk M., Wouters, Anne K., Hagedoorn, Renate S., Kester, Michel G.D., Meeuwsen, Miranda H., Wachsmann, Tassilo L.A., de Ru, Arnoud H., van Veelen, Peter A., Verdegaal, Els M.E., Falkenburg, J.H. Frederik, Heemskerk, Mirjam H.M.

Volltext

Generation of CD20-specific TCRs for TCR gene therapy of CD20low B-cell malignancies insusceptible to CD20-targeting antibodies von Jahn, Lorenz, van der Steen, Dirk M, Hagedoorn, Renate S, Hombrink, Pleun, Kester, Michel G D, Schoonakker, Marjolein P, de Ridder, Daniëlle, van Veelen, Peter A, Falkenburg, J H Frederik, Heemskerk, Mirjam H M

Volltext

Peptide Binding to HLA-E Molecules in Humans, Nonhuman Primates, and Mice Reveals Unique Binding Peptides but Remarkably Conserved Anchor Residues von Ruibal, Paula, Franken, Kees L. M. C., van Meijgaarden, Krista E., van Loon, Joeri J. F., van der Steen, Dirk, Heemskerk, Mirjam H. M., Ottenhoff, Tom H. M., Joosten, Simone A.

Volltext

T Cell Receptor Gene Therapy Targeting the Intracellular Transcription Factor Bob1 for the Treatment of Multiple Myeloma and Other B Cell Malignancies von Jahn, Lorenz, Hagedoorn, Renate S., Hombrink, Pleun, Kester, Michel G.D., van der Steen, Dirk M., Hassan, Chopie, Schoonakker, Marjolein P., van der Pijl, Erwin, van Veelen, Peter A., Falkenburg, J.H. Frederik, Heemskerk, Mirjam H.M.

Volltext

T Cell Receptors Specific for the Intracellular Transcription Factor Bob1 Allow Efficient Targeting of Human B Cell Leukemia and Multiple Myeloma von Jahn, Lorenz, Hombrink, Pleun, Kester, Michel G.D., van der Steen, Dirk M., Hagedoorn, Renate S., Hassan, Chopie, Schoonakker, Marjolein P., van der Pijl, Erwin, van Veelen, Peter A., Falkenburg, J.H. Frederik, Heemskerk, Mirjam H.M.

Volltext

Natural killer cells facilitate PRAME-specific T-cell reactivity against neuroblastoma von Spel, Lotte, Boelens, Jaap Jan, Van Der Steen, Dirk M, Blokland, Nina J G, van Noesel, Max M, Molenaar, Jan J, Heemskerk, Mirjam H M, Boes, Marianne, Nierkens, Stefan

Volltext

High Avidity PRAME Specific T Cells Derived From In Vivo HLA Mismatched Transplantation Setting Potentially Useful for Immunotherapeutic Strategies von Amir, Avital L., van der Steen, Dirk M., Hagedoorn, Renate S., Griffioen, Marieke, Falkenburg, J.H. Frederik, Heemskerk, Mirjam H.M.

Volltext

Abstract A044: Mutated NPM1 as target for immunotherapy of acute myeloid leukemia von Lee, Dyantha I. van der, Reijmers, Rogier M., Honders, M. Willy, Hagedoorn, Renate S., Jong, Rob. M. de, Kester, Michel G.D., Steen, Dirk M. van der, Ru, Arnoud H. de, Kweekel, Christiaan, Jedema, Inge, Veelken, Hendrik, Heemskerk, Mirjam M., Veelen, Peter A. van, Falkenburg, J.H. Frederik, Griffioen, Marieke

Volltext

Abstract B037: Improved CD8+ T-cell recognition of neuroblastoma after innate immune attack by natural killer cells von Spel, Lotte, Boelens, Jaap J., Til, Niek van, Steen, Dirk M. van der, Blokland, Nina J.G., Noesel, Max M. van, Molenaar, Jan J., Heemskerk, Mirjam H.M., Boes, Marianne, Nierkens, Stefan

Volltext

Stable Recombinase-Mediated Cassette Exchange in Arabidopsis Using Agrobacterium tumefaciens : Vector systems for plant research and biotechnology von LOUWERSE, Jeanine D, VAN LIER, Miranda C. M, VAN DER STEEN, Dirk M, DE VLAAM, Clementine M. T, HOOYKAAS, Paul J. J, VERGUNST, Annette C

Volltext

Erratum: A library of cancer testis specific T cell receptors for T cell receptor gene therapy von de Rooij, Marije A J, Remst, Dennis F G, van der Steen, Dirk M, Wouters, Anne K, Hagedoorn, Renate S, Kester, Michel G D, Meeuwsen, Miranda H, Wachsmann, Tassilo L A, de Ru, Arnoud H, van Veelen, Peter A, Verdegaal, Els M E, Falkenburg, J H Frederik, Heemskerk, Mirjam H M

Volltext