Targeting glutaminolysis in chondrosarcoma in context of the IDH1/2 mutation von Peterse, Elisabeth F. P., Niessen, Bertine, Addie, Ruben D., de Jong, Yvonne, Cleven, Arjen H. G., Kruisselbrink, Alwine B., van den Akker, Brendy E. W. M., Molenaar, Remco J., Cleton-Jansen, Anne-Marie, Bovée, Judith V. M. G.

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Does PARP Inhibition Sensitize Chondrosarcoma Cell Lines to Chemotherapy or Radiotherapy? Results From a Three-dimensional Spheroid Cell Model von Palubeckaitė, Ieva, Venneker, Sanne, van den Akker, Brendy E. W. M., Briaire-de Bruijn, Inge H., Boveé, Judith V. M. G.

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Extreme Diversity of the Human Vascular Mesenchymal Cell Landscape von Bruijn, Laura E., van den Akker, Brendy E. W. M., van Rhijn, Connie M., Hamming, Jaap F., Lindeman, Jan H. N.

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Multimodal profiling of chordoma immunity reveals distinct immune contextures von van Oost, Siddh, Meijer, Debora M, Ijsselsteijn, Marieke E, Roelands, Jessica P, van den Akker, Brendy E M W, van der Breggen, Ruud, Briaire-de Bruijn, Inge H, van der Ploeg, Manon, Wijers-Koster, Pauline M, Polak, Samuel B, Peul, Wilco C, van der Wal, Robert J P, de Miranda, Noel F C C, Bovee, Judith V M G

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Transforming Growth Factor β Signaling in Colorectal Cancer Cells With Microsatellite Instability Despite Biallelic Mutations in TGFBR2 von de Miranda, Noel F.C.C, van Dinther, Maarten, van den Akker, Brendy E.W.M, van Wezel, Tom, ten Dijke, Peter, Morreau, Hans

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IR/IGF1R signaling as potential target for treatment of high-grade osteosarcoma von Kuijjer, Marieke L, Peterse, Elisabeth F P, van den Akker, Brendy E W M, Briaire-de Bruijn, Inge H, Serra, Massimo, Meza-Zepeda, Leonardo A, Myklebost, Ola, Hassan, A Bassim, Hogendoorn, Pancras C W, Cleton-Jansen, Anne-Marie

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NAD Synthesis Pathway Interference Is a Viable Therapeutic Strategy for Chondrosarcoma von Peterse, Elisabeth F P, van den Akker, Brendy E W M, Niessen, Bertine, Oosting, Jan, Suijker, Johnny, de Jong, Yvonne, Danen, Erik H J, Cleton-Jansen, Anne-Marie, Bovée, Judith V M G

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Osteosarcoma Stem Cells Have Active Wnt/β-catenin and Overexpress SOX2 and KLF4 von Martins-Neves, Sara R., Corver, Willem E., Paiva-Oliveira, Daniela I., van den Akker, Brendy E. W. M., Briaire-de-Bruijn, Inge H., Bovée, Judith V. M. G., Gomes, Célia M. F., Cleton-Jansen, Anne-Marie

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Distinct Patterns of Somatic Mosaicism in the APC Gene in Neoplasms From Patients With Unexplained Adenomatous Polyposis von Jansen, Anne M.L, Crobach, Stijn, Geurts-Giele, Willemina R.R, van den Akker, Brendy E.W.M, Garcia, Marina Ventayol, Ruano, Dina, Nielsen, Maartje, Tops, Carli M.J, Wijnen, Juul T, Hes, Frederik J, van Wezel, Tom, Dinjens, Winand N.M, Morreau, Hans

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Kinome and mRNA expression profiling of high-grade osteosarcoma cell lines implies Akt signaling as possible target for therapy von Kuijjer, Marieke L, van den Akker, Brendy E W M, Hilhorst, Riet, Mommersteeg, Monique, Buddingh, Emilie P, Serra, Massimo, Bürger, Horst, Hogendoorn, Pancras C W, Cleton-Jansen, Anne-Marie

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Screening for Potential Targets for Therapy in Mesenchymal, Clear Cell, and Dedifferentiated Chondrosarcoma Reveals Bcl-2 Family Members and TGFβ as Potential Targets von van Oosterwijk, Jolieke G, Meijer, Danielle, van Ruler, Maayke A.J.H, van den Akker, Brendy E.W.M, Oosting, Jan, Krenács, Tibor, Picci, Piero, Flanagan, Adrienne M, Liegl-Atzwanger, Bernadette, Leithner, Andreas, Athanasou, Nick, Daugaard, Søren, Hogendoorn, Pancras C.W, Bovée, Judith V.M.G

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Inhibition of Bcl-2 family members sensitises soft tissue leiomyosarcomas to chemotherapy von de Graaff, Marieke A, de Rooij, Marije A J, van den Akker, Brendy E W M, Gelderblom, Hans, Chibon, Fréderic, Coindre, Jean-Michel, Marino-Enriquez, Adrian, Fletcher, Jonathan A, Cleton-Jansen, Anne-Marie, Bovée, Judith V M G

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Whole Gene Capture Analysis of 15 CRC Susceptibility Genes in Suspected Lynch Syndrome Patients von Jansen, Anne M L, Geilenkirchen, Marije A, van Wezel, Tom, Jagmohan-Changur, Shantie C, Ruano, Dina, van der Klift, Heleen M, van den Akker, Brendy E W M, Laros, Jeroen F J, van Galen, Michiel, Wagner, Anja, Letteboer, Tom G W, Gómez-García, Encarna B, Tops, Carli M J, Vasen, Hans F, Devilee, Peter, Hes, Frederik J, Morreau, Hans, Wijnen, Juul T

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Combined mismatch repair and POLE/POLD1 defects explain unresolved suspected Lynch syndrome cancers von Jansen, Anne Ml, van Wezel, Tom, van den Akker, Brendy Ewm, Ventayol Garcia, Marina, Ruano, Dina, Tops, Carli Mj, Wagner, Anja, Letteboer, Tom Gw, Gómez-García, Encarna B, Devilee, Peter, Wijnen, Juul T, Hes, Frederik J, Morreau, Hans

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Does PARP Inhibition Sensitize Chondrosarcoma Cell Lines to Chemotherapy or Radiotherapy? Results From a Three-dimensional Spheroid Cell Model von Palubeckaitė, Ieva, Venneker, Sanne, van den Akker, Brendy E. W. M., Briaire-de Bruijn, Inge H., Boveé, Judith V. M. G.

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Osteosarcoma Stem Cells Have Active Wnt/[beta]-catenin and Overexpress SOX2 and KLF4 von Martins-Neves, Sara R, Corver, Willem E, Paiva-Oliveira, Daniela I, van den Akker, Brendy E W M, Briaire-de-Bruijn, Inge H, Bovee, Judith V M G, Gomes, Célia M F, Cleton-Jansen, Anne-Marie

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Whole Gene Capture Analysis of 15 CRC Susceptibility Genes in Suspected Lynch Syndrome Patients von Jansen, Anne M L, Geilenkirchen, Marije A, van Wezel, Tom, Jagmohan-Changur, Shantie C, Ruano, Dina, van der Klift, Heleen M, van den Akker, Brendy E W M, Laros, Jeroen F J, van Galen, Michiel, Wagner, Anja, Letteboer, Tom G W, Gómez-García, Encarna B, Tops, Carli M J, Vasen, Hans F, Devilee, Peter, Hes, Frederik J, Morreau, Hans, Wijnen, Juul T

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Inhibition of Bcl-2 family members sensitises soft tissue leiomyosarcomas to chemotherapy von de Graaff, Marieke A, de Rooij, Marije A J, van den Akker, Brendy E W M, Gelderblom, Hans, Chibon, Fréderic, Coindre, Jean-Michel, Marino-Enriquez, Adrian, Fletcher, Jonathan A, Cleton-Jansen, Anne-Marie, Bovée, Judith V M G

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