ABCC6–Mediated ATP Secretion by the Liver Is the Main Source of the Mineralization Inhibitor Inorganic Pyrophosphate in the Systemic Circulation—Brief Report von Jansen, Robert S, Duijst, Suzanne, Mahakena, Sunny, Sommer, Daniela, Szeri, Flóra, Váradi, András, Plomp, Astrid, Bergen, Arthur A, Oude Elferink, Ronald P.J, Borst, Piet, van de Wetering, Koen

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Multidrug resistance-associated proteins 3, 4, and 5 von Borst, Piet, de Wolf, Cornelia, van de Wetering, Koen

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Intestinal Breast Cancer Resistance Protein (BCRP)/Bcrp1 and Multidrug Resistance Protein 3 (MRP3)/Mrp3 Are Involved in the Pharmacokinetics of Resveratrol von van de Wetering, Koen, Burkon, Alexander, Feddema, Wouter, Bot, Alice, de Jonge, Hugo, Somoza, Veronika, Borst, Piet

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Selective induction of chemotherapy resistance of mammary tumors in a conditional mouse model for hereditary breast cancer von Rottenberg, Sven, Nygren, Anders O.H, Pajic, Marina, van Leeuwen, Fijs W.B, van der Heijden, Ingrid, van de Wetering, Koen, Liu, Xiaoling, de Visser, Karin E, Gilhuijs, Kenneth G, van Tellingen, Olaf, Schouten, Jan P, Jonkers, Jos, Borst, Piet

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Negative regulation of urokinase receptor activity by a GPI-specific phospholipase C in breast cancer cells von van Veen, Michiel, Matas-Rico, Elisa, van de Wetering, Koen, Leyton-Puig, Daniela, Kedziora, Katarzyna M, De Lorenzi, Valentina, Stijf-Bultsma, Yvette, van den Broek, Bram, Jalink, Kees, Sidenius, Nicolai, Perrakis, Anastassis, Moolenaar, Wouter H

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Inorganic Pyrophosphate Deficiency Syndromes and Potential Treatments for Pathologic Tissue Calcification von Ralph, Douglas, van de Wetering, Koen, Uitto, Jouni, Li, Qiaoli

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Contribution of the drug transporter ABCG2 (breast cancer resistance protein) to resistance against anticancer nucleosides von de Wolf, Cornelia, Jansen, Robert, Yamaguchi, Hiroaki, de Haas, Marcel, van de Wetering, Koen, Wijnholds, Jan, Beijnen, Jos, Borst, Piet

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Multidrug resistance-associated proteins 3, 4, and 5 von Borst, Piet, de Wolf, Cornelia, van de Wetering, Koen

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Oral administration of pyrophosphate inhibits connective tissue calcification von Dedinszki, Dóra, Szeri, Flóra, Kozák, Eszter, Pomozi, Viola, Tőkési, Natália, Mezei, Tamás Róbert, Merczel, Kinga, Letavernier, Emmanuel, Tang, Ellie, Le Saux, Olivier, Arányi, Tamás, van de Wetering, Koen, Váradi, András

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ABCC6 prevents ectopic mineralization seen in pseudoxanthoma elasticum by inducing cellular nucleotide release von Jansen, Robert S., Küçükosmanoğlu, Aslı, de Haas, Marcel, Sapthu, Sunny, Otero, Jon Andoni, Hegman, Ilse E. M., Bergen, Arthur A. B., Gorgels, Theo G. M. F., Borst, P., van de Wetering, Koen

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Abcc6 Knockout Rat Model Highlights the Role of Liver in PPi Homeostasis in Pseudoxanthoma Elasticum von Li, Qiaoli, Kingman, Joshua, van de Wetering, Koen, Tannouri, Sami, Sundberg, John P., Uitto, Jouni

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Pyrophosphate Supplementation Prevents Chronic and Acute Calcification in ABCC6-Deficient Mice von Pomozi, Viola, Brampton, Christopher, van de Wetering, Koen, Zoll, Janna, Calio, Bianca, Pham, Kevin, Owens, Jesse B, Marh, Joel, Moisyadi, Stefan, Váradi, András, Martin, Ludovic, Bauer, Carolin, Erdmann, Jeanette, Aherrahrou, Zouhair, Le Saux, Olivier

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The membrane protein ANKH is crucial for bone mechanical performance by mediating cellular export of citrate and ATP von Szeri, Flora, Lundkvist, Stefan, Donnelly, Sylvia, Engelke, Udo F. H., Rhee, Kyu, Williams, Charlene J., Sundberg, John P., Wevers, Ron A., Tomlinson, Ryan E., Jansen, Robert S., van de Wetering, Koen

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N-lactoyl-amino acids are ubiquitous metabolites that originate from CNDP2-mediated reverse proteolysis of lactate and amino acids von Jansen, Robert S., Addie, Ruben, Merkx, Remco, Fish, Alexander, Mahakena, Sunny, Bleijerveld, Onno B., Altelaar, Maarten, IJlst, Lodewijk, Wanders, Ronald J., Borst, P., van de Wetering, Koen

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Multidrug resistance-associated protein 9 (ABCC12) is present in mouse and boar sperm von Ono, Nobuhito, Van der Heijden, Ingrid, Scheffer, George L, Van de Wetering, Koen, Van Deemter, Elizabeth, De Haas, Marcel, Boerke, Arjan, Gadella, Bart M, De Rooij, Dirk G, Neefjes, Jacques J, Groothuis, Tom A M, Oomen, Lauran, Brocks, Lenny, Ishikawa, Toshihisa, Borst, Piet

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Identification of multidrug resistance protein 1 (MRP1/ABCC1) as a molecular gate for cellular export of cobalamin von Beedholm-Ebsen, Rasmus, van de Wetering, Koen, Hardlei, Tore, Nexø, Ebba, Borst, Piet, Moestrup, Søren K.

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Loss of function mutation in Ank causes aberrant mineralization and acquisition of osteoblast-like-phenotype by the cells of the intervertebral disc von Ohnishi, Takashi, Tran, Victoria, Sao, Kimheak, Ramteke, Pranay, Querido, William, Barve, Ruteja A., van de Wetering, Koen, Risbud, Makarand V.

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Mutagenic Analysis of the Putative ABCC6 Substrate-Binding Cavity Using a New Homology Model von Szeri, Flora, Corradi, Valentina, Niaziorimi, Fatemeh, Donnelly, Sylvia, Conseil, Gwenaelle, Cole, Susan P. C., Tieleman, D. Peter, van de Wetering, Koen

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Does the absence of ABCC6 (Multidrug Resistance Protein 6) in patients with Pseudoxanthoma elasticum prevent the liver from providing sufficient vitamin K to the periphery? von Borst, Piet, van de Wetering, Koen, Schlingemann, Reinier

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A new perspective on intervertebral disc calcification-from bench to bedside von Novais, Emanuel J, Narayanan, Rajkishen, Canseco, Jose A, van de Wetering, Koen, Kepler, Christopher K, Hilibrand, Alan S, Vaccaro, Alexander R, Risbud, Makarand V

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