396 FASTING REDUCES LIVER FIBROSIS IN A MOUSE MODEL OF CHRONIC CHOLANGIOPATHY von Sokolovic, A, van Roomen, C.P.A.A, Ottenhoff, R, Aten, J, Hiralall, J.K, Bosma, P.J, Elferink, R.P.J. Oude, Groen, A.K, Sokolovic, M

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Humanized Anti-IgE mAb Hu-901 Prevents the Activation of Allergen-Specific T Cells von van Neerven, R.J.J., van Roomen, C.P.A.A., Thomas, W.R., de Boer, M., Knol, E.F., Davis, F.M.

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Improvement of hyperlipidemia and atherosclerosis with lipophilic iminosugars von Lombardo, E., Bietrix, F.M., van Roomen, C.P.A.A., Ottenhoff, R., Groen, A.K., Aerts, J.M.F.G.

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High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages von Hoepel, W., Chen, H.J., Geyer, C.E., Allahverdiyeva, S., Manz, X.D., Taeye, S.W. de, Aman, J., Mes, L., Steenhuis, M., Griffith, G.R., Bonta, P.I., Brouwer, P.J.M., Caniels, T.G., Straten, K. van der, Golebski, K., Jonkers, R.E., Larsen, M.D., Linty, F., Nouta, J., Roomen, C.P.A.A. van, Baarle, F.E.H.P. van, Drunen, C.M. van, Wolbink, G., Vlaar, A.P.J., Bree, G.J. de, Sanders, R.W., Willemsen, L., Neele, A.E., Beek, D. van de, Rispens, T., Wuhrer, M., Bogaard, H.J., Gils, M.J. van, Vidarsson, G., Winther, M. de, Dunnen, J. den

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Investigations on therapeutic glucocerebrosidases through paired detection with fluorescent activity-based probes von Kallemeijn, W.W., Scheij, S., Hoogendoorn, S., Witte, M.D., Herrera Moro Chao, D., Roomen, C.P.A.A. van, Ottenhoff, R., Overkleeft, H.S., Boot, R.G., Aerts, J.M.F.G.

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Stabilization of Glucocerebrosidase by Active Site Occupancy von Ben Bdira, F., Kallemeijn, W.W., Oussoren, S.V., Scheij, S., Bleijlevens, B., Florea, B.I., Roomen, C.P.A.A. van, Ottenhoff, R., Kooten, M.J.F.M. van, Walvoort, M.T.C., Witte, M.D., Boot, R.G., Ubbink, M., Overkleeft, H.S., Aerts, J.M.F.G.

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Reducing GBA2 Activity Ameliorates Neuropathology in Niemann-Pick Type C Mice von Marques, A.R.A., Aten, J., Ottenhoff, R., Roomen, C.P.A.A. van, Moro, D.H., Claessen, N., Veloz, M.F.V., Zhou, K., Lin, Z., Mirzaian, M., Boot, R.G., Zeeuw, C.I. de, Overkleeft, H.S., Yildiz, Y., Aerts, J.M.F.G.

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Correction of Liver Steatosis by a Hydrophobic Iminosugar Modulating Glycosphingolipids Metabolism von Lombardo, E., Roomen, C.P.A.A. van, Van Puijvelde, G.H., Ottenhoff, R., Eijk, M. van, Aten, J., Kuiper, J., Overkleeft, H.S., Groen, A.K., Verhoeven, A.J., Aerts, J.M.F.G., Bietrix, F.

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Reducing Glycosphingolipid Content in Adipose Tissue of Obese Mice Restores Insulin Sensitivity, Adipogenesis and Reduces Inflammation von Eijk, M.C. van, Aten, J., Bijl, N., Ottenhoff, R., Roomen, C.P.A.A. van, Dubbelhuis, P.F., Seeman, I., Ghauharali-Vlugt van der, K., Overkleeft, H.S., Arbeeny, C., Groen, A.K., Aerts, J.M.F.G.

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The polycomb repressive complex 2 (PRC2) in macrophages and atherosclerosis von Neele, A.E., Willemsen, L., Chen, H.-J., Gijbels, M.J.J., Roomen, C.P.A.A., Griffith, G.R., Van Der Velden, S., Hoeksema, M.A., Prange, K.H.M., Boshuizen, M.C., Van Den Bossche, J., Tool, A.T., Matlung, H.L., Van Den Berg, T.K., Lutgens, E., De Winther, M.P.J.

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Histone methyltransferase DOT1L regulates macrophage inflammatory responses and lipid metabolism von Willemsen, L., Neele, A.E., Prange, K.H.M., Roomen, C.P.A.A., Bruinenberg, D. A.M. Lotgerink, Den Toom, M., Griffith, G.R., Chen, H.-J., Beckers, L., Bosmans, L.A., Binder, C.J., Van Leeuwen, F., Jacobs, H., De Winther, M.P.J.

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