Snail Regulates MyoD Binding-Site Occupancy to Direct Enhancer Switching and Differentiation-Specific Transcription in Myogenesis von Soleimani, Vahab D., Yin, Hang, Jahani-Asl, Arezu, Ming, Hong, Kockx, Christel E.M., van Ijcken, Wilfred F.J., Grosveld, Frank, Rudnicki, Michael A.

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The core spliceosome as target and effector of non-canonical ATM signalling von Tresini, Maria, Warmerdam, Daniël O., Kolovos, Petros, Snijder, Loes, Vrouwe, Mischa G., Demmers, Jeroen A. A., van IJcken, Wilfred F. J., Grosveld, Frank G., Medema, René H., Hoeijmakers, Jan H. J., Mullenders, Leon H. F., Vermeulen, Wim, Marteijn, Jurgen A.

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The Isl1/Ldb1 Complex Orchestrates Genome-wide Chromatin Organization to Instruct Differentiation of Multipotent Cardiac Progenitors von Caputo, Luca, Witzel, Hagen R., Kolovos, Petros, Cheedipudi, Sirisha, Looso, Mario, Mylona, Athina, van IJcken, Wilfred F.J., Laugwitz, Karl-Ludwig, Evans, Sylvia M., Braun, Thomas, Soler, Eric, Grosveld, Frank, Dobreva, Gergana

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Inefficient DNA Repair Is an Aging-Related Modifier of Parkinson’s Disease von Sepe, Sara, Milanese, Chiara, Gabriels, Sylvia, Derks, Kasper W.J., Payan-Gomez, Cesar, van IJcken, Wilfred F.J., Rijksen, Yvonne M.A., Nigg, Alex L., Moreno, Sandra, Cerri, Silvia, Blandini, Fabio, Hoeijmakers, Jan H.J., Mastroberardino, Pier G.

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Transcriptional Dominance of Pax7 in Adult Myogenesis Is Due to High-Affinity Recognition of Homeodomain Motifs von Soleimani, Vahab D., Punch, Vincent G., Kawabe, Yoh-ichi, Jones, Andrew E., Palidwor, Gareth A., Porter, Christopher J., Cross, Joe W., Carvajal, Jaime J., Kockx, Christel E.M., van IJcken, Wilfred F.J., Perkins, Theodore J., Rigby, Peter W.J., Grosveld, Frank, Rudnicki, Michael A.

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Contribution of rare and common variants determine complex diseases—Hirschsprung disease as a model von Alves, Maria M., Sribudiani, Yunia, Brouwer, Rutger W.W., Amiel, Jeanne, Antiñolo, Guillermo, Borrego, Salud, Ceccherini, Isabella, Chakravarti, Aravinda, Fernández, Raquel M., Garcia-Barcelo, Maria-Mercè, Griseri, Paola, Lyonnet, Stanislas, Tam, Paul K., van IJcken, Wilfred F.J., Eggen, Bart J.L., te Meerman, Gerard J., Hofstra, Robert M.W.

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Metabolic Enzyme IMPDH Is Also a Transcription Factor Regulated by Cellular State von Kozhevnikova, Elena N., van der Knaap, Jan A., Pindyurin, Alexey V., Ozgur, Zeliha, van Ijcken, Wilfred F.J., Moshkin, Yuri M., Verrijzer, C. Peter

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Endogenous WNT signals mediate BMP-induced and spontaneous differentiation of epiblast stem cells and human embryonic stem cells von Kurek, Dorota, Neagu, Alex, Tastemel, Melodi, Tüysüz, Nesrin, Lehmann, Johannes, van de Werken, Harmen J G, Philipsen, Sjaak, van der Linden, Reinier, Maas, Alex, van IJcken, Wilfred F J, Drukker, Micha, Ten Berge, Derk

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Balancing of Histone H3K4 Methylation States by the Kdm5c/SMCX Histone Demethylase Modulates Promoter and Enhancer Function von Outchkourov, Nikolay S., Muiño, Jose M., Kaufmann, Kerstin, van IJcken, Wilfred F.J., Koerkamp, Marian J. Groot, van Leenen, Dik, de Graaf, Petra, Holstege, Frank C.P., Grosveld, Frank G., Timmers, H.T. Marc

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Pathogen-induced activation of disease-suppressive functions in the endophytic root microbiome von Carrión, Víctor J., Perez-Jaramillo, Juan, Cordovez, Viviane, Tracanna, Vittorio, de Hollander, Mattias, Ruiz-Buck, Daniel, Mendes, Lucas W., van Ijcken, Wilfred F.J., Gomez-Exposito, Ruth, Elsayed, Somayah S., Mohanraju, Prarthana, Arifah, Adini, van der Oost, John, Paulson, Joseph N., Mendes, Rodrigo, van Wezel, Gilles P., Medema, Marnix H., Raaijmakers, Jos M.

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PRC2 Facilitates the Regulatory Topology Required for Poised Enhancer Function during Pluripotent Stem Cell Differentiation von Cruz-Molina, Sara, Respuela, Patricia, Tebartz, Christina, Kolovos, Petros, Nikolic, Milos, Fueyo, Raquel, van Ijcken, Wilfred F.J., Grosveld, Frank, Frommolt, Peter, Bazzi, Hisham, Rada-Iglesias, Alvaro

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A cohesin-independent role for NIPBL at promoters provides insights in CdLS von Zuin, Jessica, Franke, Vedran, van Ijcken, Wilfred F J, van der Sloot, Antoine, Krantz, Ian D, van der Reijden, Michael I J A, Nakato, Ryuichiro, Lenhard, Boris, Wendt, Kerstin S

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Two independent transcription initiation codes overlap on vertebrate core promoters von Haberle, Vanja, Li, Nan, Hadzhiev, Yavor, Plessy, Charles, Previti, Christopher, Nepal, Chirag, Gehrig, Jochen, Dong, Xianjun, Akalin, Altuna, Suzuki, Ana Maria, van IJcken, Wilfred F. J., Armant, Olivier, Ferg, Marco, Strähle, Uwe, Carninci, Piero, Müller, Ferenc, Lenhard, Boris

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Whole-transcriptome analysis of endothelial to hematopoietic stem cell transition reveals a requirement for Gpr56 in HSC generation von Solaimani Kartalaei, Parham, Yamada-Inagawa, Tomoko, Vink, Chris S, de Pater, Emma, van der Linden, Reinier, Marks-Bluth, Jonathon, van der Sloot, Anthon, van den Hout, Mirjam, Yokomizo, Tomomasa, van Schaick-Solernó, M Lucila, Delwel, Ruud, Pimanda, John E, van IJcken, Wilfred F J, Dzierzak, Elaine

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Notch signaling licenses allergic airway inflammation by promoting Th2 cell lymph node egress von Tindemans, Irma, van Schoonhoven, Anne, KleinJan, Alex, de Bruijn, Marjolein Jw, Lukkes, Melanie, van Nimwegen, Menno, van den Branden, Anouk, Bergen, Ingrid M, Corneth, Odilia Bj, van IJcken, Wilfred Fj, Stadhouders, Ralph, Hendriks, Rudi W

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Human age estimation from blood using mRNA, DNA methylation, DNA rearrangement, and telomere length von Zubakov, Dmitry, Liu, Fan, Kokmeijer, Iris, Choi, Ying, van Meurs, Joyce B.J, van IJcken, Wilfred F.J, Uitterlinden, André G, Hofman, Albert, Broer, Linda, van Duijn, Cornelia M, Lewin, Jörn, Kayser, Manfred

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Loss-of-Function Variants in MYLK Cause Recessive Megacystis Microcolon Intestinal Hypoperistalsis Syndrome von Halim, Danny, Brosens, Erwin, Muller, Françoise, Wangler, Michael F., Beaudet, Arthur L., Lupski, James R., Akdemir, Zeynep H. Coban, Doukas, Michael, Stoop, Hans J., de Graaf, Bianca M., Brouwer, Rutger W.W., van Ijcken, Wilfred F.J., Oury, Jean-François, Rosenblatt, Jonathan, Burns, Alan J., Tibboel, Dick, Hofstra, Robert M.W., Alves, Maria M.

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MAU2 and NIPBL Variants Impair the Heterodimerization of the Cohesin Loader Subunits and Cause Cornelia de Lange Syndrome von Parenti, Ilaria, Diab, Farah, Gil, Sara Ruiz, Mulugeta, Eskeatnaf, Casa, Valentina, Berutti, Riccardo, Brouwer, Rutger W.W., Dupé, Valerie, Eckhold, Juliane, Graf, Elisabeth, Puisac, Beatriz, Ramos, Feliciano, Schwarzmayr, Thomas, Gines, Macarena Moronta, van Staveren, Thomas, van IJcken, Wilfred F.J., Strom, Tim M., Pié, Juan, Watrin, Erwan, Kaiser, Frank J., Wendt, Kerstin S.

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Large-Scale Expansion of Human iPSC-Derived Skeletal Muscle Cells for Disease Modeling and Cell-Based Therapeutic Strategies von van der Wal, Erik, Herrero-Hernandez, Pablo, Wan, Raymond, Broeders, Mike, in 't Groen, Stijn L.M., van Gestel, Tom J.M., van IJcken, Wilfred F.J., Cheung, Tom H., van der Ploeg, Ans T., Schaaf, Gerben J., Pijnappel, W.W.M. Pim

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LSD1/KDM1A and GFI1B repress endothelial fate and induce hematopoietic fate in induced pluripotent stem cell-derived hemogenic endotheliums von Zhang, Huan, Hansen, Marten, Di Summa, Franca, Von Lindern, Marieke, Gillemans, Nynke, Van IJcken, Wilfred F.J., Svendsen, Arthur Flohr, Philipsen, Sjaak, Van der Reijden, Bert, Varga, Eszter, Van den Akker, Emile

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