Bioanalysis of ibrutinib, and its dihydrodiol- and glutathione cycle metabolites by liquid chromatography-tandem mass spectrometry von Rood, J.J.M., Dormans, P.J.A., van Haren, M.J., Schellens, J.H.M., Beijnen, J.H., Sparidans, R.W.

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Bioanalysis of EGFRm inhibitor osimertinib, and its glutathione cycle- and desmethyl metabolites by liquid chromatography-tandem mass spectrometry von Rood, J.J.M., van Haren, M.J., Beijnen, J.H., Sparidans, R.W.

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Transition state mimics as inhibitors of methyltransferase enzymes von van Haren, M.J

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Novel cephalosporin conjugates display potent and selective inhibition of imipenemase-type metallo-β-lactamases von Tehrani, K.H.M.E., Wade, N., Mashayekhi, V., Brüchle, N.C., Jespers, W., Voskuil, K., Pesce, D., Westen, G.J.P. van, Martin, N.I.

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Nicotinamide N-Methyl Transferase (NNMT): an emerging therapeutic target von Gao, Y., Martin, N.I., Haren, M.J. van

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Synthetic studies with bacitracin A and preparation of analogues containing alternative zinc binding groups von Buijs, N., Vlaming, H.C., Haren, M.J. van, Martin, N.I.

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Peptidic transition state analogues as PRMT inhibitors von Zhang, Y., Haren, M.J. van, Martin, N.I.

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A direct assay for measuring the activity and inhibition of coactivator-associated arginine methyltransferase 1 von Zhang, Y., Haren, M.J. van, Marechal, N., Troffer-Charlier, N., Cura, V., Cavarelli, J., Martin, N.I.

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Structural studies provide new insights into the role of lysine acetylation on substrate recognition by CARM1 and inform the design of potent peptidomimetic inhibitors von Zhang, Y., Marechal, N., Haren, M.J. van, Troffer-Charlier, N., Cura, V., Cavarelli, J., Martin, N.I.

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Mechanistic investigations of metallo-β-lactamase inhibitors: strong zinc binding is not required for potent enzyme inhibition von Wade, N., Tehrani, K.H.M.E., Brüchle, N.C., Haren, M.J. van, Mashayekhi, V., Martin, N.I.

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Mechanistic investigations of metallo‐β‐lactamase inhibitors: strong zinc binding Is not required for potent enzyme inhibition von Wade, N., Tehrani, K.H.M.E., Brüchle, N.C., Haren, M.J. van, Mashayekhi, Vi, Martin, N.I.

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Cephalosporin prodrug inhibitors overcome metallo-β-lactamase driven antibiotic resistance von Haren, M.J. van, Tehrani, K.H.M.E., Kotsogianni, I., Wade, N., Brüchle, N., Mashayekhi, V., Martin, N.I.

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PRMT Inhibitors von Haren, M.J. van, Martin, N.I.

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Cephalosporin prodrug inhibitors overcome metallo‐β‐lactamase driven antibiotic resistance von Haren, M.J. van, Tehrani, K.H.M.E., Kotsogianni Teftsoglou, A.I., Wade, N., Brüchle, N.C., Mashayekhi, V., Martin, N.I.

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Small molecule carboxylates inhibit metallo-β-lactamases and resensitize carbapenem-resistant bacteria to meropenem von Tehrani, K.H.M.E., Brüchle, N.C., Wade, N., Mashayekhi, V., Pesce, D., Haren, M.J. van, Martin, N.I.

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Esterase-sensitive prodrugs of a potent bisubstrate inhibitor of Nicotinamide N-Methyltransferase (NNMT) display cellular activity von Haren, M.J. van, Gao, Y., Buijs, N., Campagna, R., Sartini, D., Emanuelli, M., Mateuszuk, L., Kij, A., Chlopicki, S., Martinez de Castilla, P.E., Schiffelers, R., Martin, N.I.

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Novel Cephalosporin conjugates display potent and selective inhibition of Imipenemase-type Metallo-β-Lactamases von Tehrani, K.H.M.E., Wade, N., Mashayekhi, V., Brüchle, N., Jespers, W., Voskuil, K., Pesce, D., Haren, M.J. van, Westen, G.J.P. van, Martin, N.I.

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Aminocarboxylic acids related to aspergillomarasmine A (AMA) and ethylenediamine-N,N′-disuccinic acid (EDDS) are strong zinc-binders and inhibitors of the metallo-beta-lactamase ND... von Tehrani, K.H.M.E., Fu, H., Brüchle, N.C., Mashayekhi, V., Prats Luján, A., Haren, M.J. van, Poelarends, G.J., Martin, N.I.

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Potent inhibition of nicotinamide N-methyltransferase by alkene linked bisubstrate mimics bearing electron deficient aromatics von Gao, Y., Haren, M.J. van, Buijs, N., Innocenti, P., Zhang, Y., Sartini, D., Campagna, R., Emanuelli, M., Parsons, R.B., Jespers, W., Gutiérrez-de-Terán, H., Westen, G.J.P. van, Martin, N.I.

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Macrocyclic peptides as allosteric inhibitors of nicotinamide n-methyltransferase (NNMT) von Haren, M.J. van, Zhang, Y., Thijssen, V., Buijs, N.P., Gao, Y., Mateuszuk, L., Fedak, F.A., Kij, A., Campagna, R., Sartini, D., Emanuelli, M., Chlopicki, S., Jongkees, S.A.K., Martin, N.I.

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