High-dimensional cytometric analysis of colorectal cancer reveals novel mediators of antitumour immunity von de Vries, Natasja L, van Unen, Vincent, Ijsselsteijn, Marieke E, Abdelaal, Tamim, van der Breggen, Ruud, Farina Sarasqueta, Arantza, Mahfouz, Ahmed, Peeters, Koen C M J, Höllt, Thomas, Lelieveldt, Boudewijn P F, Koning, Frits, de Miranda, Noel F C C

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Transcriptional profiling of human familial longevity indicates a role for ASF1A and IL7R von Passtoors, Willemijn M, Boer, Judith M, Goeman, Jelle J, Akker, Erik B van den, Deelen, Joris, Zwaan, Bas J, Scarborough, Ann, Breggen, Ruud van der, Vossen, Rolf H A M, Houwing-Duistermaat, Jeanine J, Ommen, Gert Jan B van, Westendorp, Rudi G J, van Heemst, Diana, de Craen, Anton J M, White, Andrew J, Gunn, David A, Beekman, Marian, Slagboom, P Eline

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A 40-Marker Panel for High Dimensional Characterization of Cancer Immune Microenvironments by Imaging Mass Cytometry von Ijsselsteijn, Marieke E, van der Breggen, Ruud, Farina Sarasqueta, Arantza, Koning, Frits, de Miranda, Noel F C C

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Revisiting immune escape in colorectal cancer in the era of immunotherapy von Ijsselsteijn, Marieke Erica, Petitprez, Florent, Lacroix, Laetitia, Ruano, Dina, van der Breggen, Ruud, Julie, Catherine, Morreau, Hans, Sautès-Fridman, Catherine, Fridman, Wolf Herman, de Miranda, Noel Filipe da Cunha Carvalho

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Annotating Transcriptional Effects of Genetic Variants in Disease‐Relevant Tissue: Transcriptome‐Wide Allelic Imbalance in Osteoarthritic Cartilage von Hollander, Wouter, Pulyakhina, Irina, Boer, Cindy, Bomer, Nils, Breggen, Ruud, Arindrarto, Wibowo, Couthino de Almeida, Rodrigo, Lakenberg, Nico, Sentner, Thom, Laros, Jeroen F. J., ‘t Hoen, Peter A. C., Slagboom, Eline P. E., Nelissen, Rob G. H. H., Meurs, Joyce, Ramos, Yolande F. M., Meulenbelt, Ingrid

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Genes involved in the osteoarthritis process identified through genome wide expression analysis in articular cartilage; the RAAK study von Ramos, Yolande F M, den Hollander, Wouter, Bovée, Judith V M G, Bomer, Nils, van der Breggen, Ruud, Lakenberg, Nico, Keurentjes, J Christiaan, Goeman, Jelle J, Slagboom, P Eline, Nelissen, Rob G H H, Bos, Steffan D, Meulenbelt, Ingrid

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Neoantigen-specific immunity in low mutation burden colorectal cancers of the consensus molecular subtype 4 von van den Bulk, Jitske, Verdegaal, Els M E, Ruano, Dina, Ijsselsteijn, Marieke E, Visser, Marten, van der Breggen, Ruud, Duhen, Thomas, van der Ploeg, Manon, de Vries, Natasja L, Oosting, Jan, Peeters, Koen C M J, Weinberg, Andrew D, Farina-Sarasqueta, Arantza, van der Burg, Sjoerd H, de Miranda, Noel F C C

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Identification and systematic annotation of tissue-specific differentially methylated regions using the Illumina 450k array von Slieker, Roderick C, Bos, Steffan D, Goeman, Jelle J, Bovée, Judith Vmg, Talens, Rudolf P, van der Breggen, Ruud, Suchiman, H Eka D, Lameijer, Eric-Wubbo, Putter, Hein, van den Akker, Erik B, Zhang, Yanju, Jukema, J Wouter, Slagboom, P Eline, Meulenbelt, Ingrid, Heijmans, Bastiaan T

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Occupational exposure to gases/fumes and mineral dust affect DNA methylation levels of genes regulating expression von van der Plaat, Diana A, Vonk, Judith M, Terzikhan, Natalie, de Jong, Kim, de Vries, Maaike, La Bastide-van Gemert, Sacha, van Diemen, Cleo C, Lahousse, Lies, Brusselle, Guy G, Nedeljkovic, Ivana, Amin, Najaf, Kromhout, Hans, Vermeulen, Roel C H, Postma, Dirkje S, van Duijn, Cornelia M, Boezen, H Marike

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A meta-analysis of European and Asian cohorts reveals a global role of a functional SNP in the 5′ UTR of GDF5 with osteoarthritis susceptibility von Chapman, Kay, Takahashi, Atsushi, Meulenbelt, Ingrid, Watson, Chris, Rodriguez-Lopez, Julio, Egli, Rainer, Tsezou, Aspasia, Malizos, Konstantinos N., Kloppenburg, Margreet, Shi, Dongquan, Southam, Lorraine, van der Breggen, Ruud, Donn, Rachelle, Qin, Jianghui, Doherty, Michael, Slagboom, P. Eline, Wallis, Gillian, Kamatani, Naoyuki, Jiang, Qing, Gonzalez, Antonio, Loughlin, John, Ikegawa, Shiro

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Identification of DIO2 as a new susceptibility locus for symptomatic osteoarthritis von Meulenbelt, Ingrid, Min, Josine L., Bos, Steffan, Riyazi, Naghmeh, Houwing-Duistermaat, Jeanine J., van der Wijk, Henk-Jan, Kroon, Herman M., Nakajima, Masahiro, Ikegawa, Shiro, Uitterlinden, André G., van Meurs, Joyce B.J., van der Deure, Wendy M., Visser, Theo J., Seymour, Albert B., Lakenberg, Nico, van der Breggen, Ruud, Kremer, Dennis, van Duijn, Cornelia M., Kloppenburg, Margreet, Loughlin, John, Slagboom, P. Eline

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Genome-wide association study (GWAS)-identified disease risk alleles do not compromise human longevity von Beekman, Marian, Nederstigt, Christa, Suchiman, H. Eka D., Kremer, Dennis, van der Breggen, Ruud, Lakenberg, Nico, Alemayehu, Wendimagegn Ghidey, de Craen, Anton J. M., Westendorp, Rudi G. J., Boomsma, Dorret I., de Geus, Eco J. C., Houwing-Duistermaat, Jeanine J., Heijmans, Bastiaan T., Slagboom, P. Eline, Cantor, Charles R.

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Transcriptional Associations of Osteoarthritis‐Mediated Loss of Epigenetic Control in Articular Cartilage von den Hollander, Wouter, Ramos, Yolande F. M., Bomer, Nils, Elzinga, Stefan, van der Breggen, Ruud, Lakenberg, Nico, de Dijcker, Wesley J., Suchiman, H. Eka D., Duijnisveld, Bouke J., Houwing‐Duistermaat, Jeanine J., Slagboom, P. Eline, Bos, Steffan D., Nelissen, Rob G. H. H., Meulenbelt, Ingrid

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CD103 and CD39 coexpression identifies neoantigen-specific cytotoxic T cells in colorectal cancers with low mutation burden von van den Bulk, Jitske, van der Ploeg, Manon, Ijsselsteijn, Marieke E, Ruano, Dina, van der Breggen, Ruud, Duhen, Rebekka, Peeters, Koen C M J, Fariña-Sarasqueta, Arantza, Verdegaal, Els M E, van der Burg, Sjoerd H, Duhen, Thomas, de Miranda, Noel F C C

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The effect of forced exercise on knee joints in Dio2−/− mice: type II iodothyronine deiodinase-deficient mice are less prone to develop OA-like cartilage damage upon excessive mech... von Bomer, Nils, Cornelis, Frederique M F, Ramos, Yolande FM, den Hollander, Wouter, Storms, Lies, van der Breggen, Ruud, Lakenberg, Nico, Slagboom, P Eline, Meulenbelt, Ingrid, Lories, Rik JL

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Multimodal profiling of chordoma immunity reveals distinct immune contextures von van Oost, Siddh, Meijer, Debora M, Ijsselsteijn, Marieke E, Roelands, Jessica P, van den Akker, Brendy E M W, van der Breggen, Ruud, Briaire-de Bruijn, Inge H, van der Ploeg, Manon, Wijers-Koster, Pauline M, Polak, Samuel B, Peul, Wilco C, van der Wal, Robert J P, de Miranda, Noel F C C, Bovee, Judith V M G

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Increased type II deiodinase protein in OA-affected cartilage and allelic imbalance of OA risk polymorphism rs225014 at DIO2 in human OA joint tissues von Bos, Steffan D, Bovée, Judith V M G, Duijnisveld, Bouke J, Raine, Emma V A, van Dalen, Wouter J, Ramos, Yolande F M, van der Breggen, Ruud, Nelissen, Rob G H H, Slagboom, P Eline, Loughlin, John, Meulenbelt, Ingrid

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IL7R gene expression network associates with human healthy ageing von Passtoors, Willemijn M, van den Akker, Erik B, Deelen, Joris, Maier, Andrea B, van der Breggen, Ruud, Jansen, Rick, Trompet, Stella, van Heemst, Diana, Derhovanessian, Evelyna, Pawelec, Graham, van Ommen, Gert-Jan B, Slagboom, P Eline, Beekman, Marian

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Aberrant Calreticulin Expression in Articular Cartilage of Dio2 Deficient Mice von Bomer, Nils, Cornelis, Frederique M F, Ramos, Yolande F M, den Hollander, Wouter, Lakenberg, Nico, van der Breggen, Ruud, Storms, Lies, Slagboom, P Eline, Lories, Rik J U, Meulenbelt, Ingrid

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Large replication study and meta-analyses of DVWA as an osteoarthritis susceptibility locus in European and Asian populations von Meulenbelt, Ingrid, Chapman, Kay, Dieguez-Gonzalez, Rebeca, Shi, Dongquan, Tsezou, Aspasia, Dai, Jin, Malizos, Konstantinos N., Kloppenburg, Margreet, Carr, Andrew, Nakajima, Masahiro, van der Breggen, Ruud, Lakenberg, Nico, Gomez-Reino, Juan J., Jiang, Qing, Ikegawa, Shiro, Gonzalez, Antonio, Loughlin, John, Slagboom, Eline P.

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