Structure- and function-based design of Plasmodium-selective proteasome inhibitors von Li, Hao, O’Donoghue, Anthony J., van der Linden, Wouter A., Xie, Stanley C., Yoo, Euna, Foe, Ian T., Tilley, Leann, Craik, Charles S., da Fonseca, Paula C. A., Bogyo, Matthew

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Disruption of glycolytic flux is a signal for inflammasome signaling and pyroptotic cell death von Sanman, Laura E, Qian, Yu, Eisele, Nicholas A, Ng, Tessie M, van der Linden, Wouter A, Monack, Denise M, Weerapana, Eranthie, Bogyo, Matthew

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Bifunctional Probes of Cathepsin Protease Activity and pH Reveal Alterations in Endolysosomal pH during Bacterial Infection von Sanman, Laura E., van der Linden, Wouter A., Verdoes, Martijn, Bogyo, Matthew

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Global Analysis of Palmitoylated Proteins in Toxoplasma gondii von Foe, Ian T., Child, Matthew A., Majmudar, Jaimeen D., Krishnamurthy, Shruthi, van der Linden, Wouter A., Ward, Gary E., Martin, Brent R., Bogyo, Matthew

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Non-invasive Imaging of Idiopathic Pulmonary Fibrosis Using Cathepsin Protease Probes von Withana, Nimali P., Ma, Xiaowei, McGuire, Helen M., Verdoes, Martijn, van der Linden, Wouter A., Ofori, Leslie O., Zhang, Ruiping, Li, Hao, Sanman, Laura E., Wei, Ke, Yao, Shaobo, Wu, Peilin, Li, Fang, Huang, Hui, Xu, Zuojun, Wolters, Paul J., Rosen, Glenn D., Collard, Harold R., Zhu, Zhaohui, Cheng, Zhen, Bogyo, Matthew

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Development of an activity-based probe for acyl-protein thioesterases von Garland, Megan, Schulze, Christopher J, Foe, Ian T, van der Linden, Wouter A, Child, Matthew A, Bogyo, Matthew

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Bioorthogonal Chemistry: Applications in Activity-Based Protein Profiling von Willems, Lianne I, van der Linden, Wouter A, Li, Nan, Li, Kah-Yee, Liu, Nora, Hoogendoorn, Sascha, van der Marel, Gijs A, Florea, Bogdan I, Overkleeft, Herman S

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The novel β2-selective proteasome inhibitor LU-102 synergizes with bortezomib and carfilzomib to overcome proteasome inhibitor resistance of myeloma cells von Kraus, Marianne, Bader, Juergen, Geurink, Paul P, Weyburne, Emily S, Mirabella, Anne C, Silzle, Tobias, Shabaneh, Tamer B, van der Linden, Wouter A, de Bruin, Gerjan, Haile, Sarah R, van Rooden, Eva, Appenzeller, Christina, Li, Nan, Kisselev, Alexei F, Overkleeft, Herman, Driessen, Christoph

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Deletion of the rodent malaria ortholog for falcipain-1 highlights differences between hepatic and blood stage merozoites von Hopp, Christine S, Bennett, Brandy L, Mishra, Satish, Lehmann, Christine, Hanson, Kirsten K, Lin, Jing-Wen, Rousseau, Kimberly, Carvalho, Filomena A, van der Linden, Wouter A, Santos, Nuno C, Bogyo, Matthew, Khan, Shahid M, Heussler, Volker, Sinnis, Photini

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Cysteine cathepsin activity suppresses osteoclastogenesis of myeloid-derived suppressor cells in breast cancer von Edgington-Mitchell, Laura E, Rautela, Jai, Duivenvoorden, Hendrika M, Jayatilleke, Krishnath M, van der Linden, Wouter A, Verdoes, Martijn, Bogyo, Matthew, Parker, Belinda S

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Legumain is activated in macrophages during pancreatitis von Edgington-Mitchell, Laura E, Wartmann, Thomas, Fleming, Alicia K, Gocheva, Vasilena, van der Linden, Wouter A, Withana, Nimali P, Verdoes, Martijn, Aurelio, Luigi, Edgington-Mitchell, Daniel, Lieu, TinaMarie, Parker, Belinda S, Graham, Bim, Reinheckel, Thomas, Furness, John B, Joyce, Johanna A, Storz, Peter, Halangk, Walter, Bogyo, Matthew, Bunnett, Nigel W

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Proteasome Inhibitors: An Expanding Army Attacking a Unique Target von Kisselev, Alexei F., van der Linden, Wouter A., Overkleeft, Herman S.

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Toxoplasma DJ-1 Regulates Organelle Secretion by a Direct Interaction with Calcium-Dependent Protein Kinase 1 von Child, Matthew A, Garland, Megan, Foe, Ian, Madzelan, Peter, Treeck, Moritz, van der Linden, Wouter A, Oresic Bender, Kristina, Weerapana, Eranthie, Wilson, Mark A, Boothroyd, John C, Reese, Michael L, Bogyo, Matthew

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Improved Quenched Fluorescent Probe for Imaging of Cysteine Cathepsin Activity von Verdoes, Martijn, Oresic Bender, Kristina, Segal, Ehud, van der Linden, Wouter A, Syed, Salahuddin, Withana, Nimali P, Sanman, Laura E, Bogyo, Matthew

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Two-step bioorthogonal activity-based proteasome profiling using copper-free click reagents: A comparative study von van der Linden, Wouter A., Li, Nan, Hoogendoorn, Sascha, Ruben, Mark, Verdoes, Martijn, Guo, Jun, Boons, Geert-Jan, van der Marel, Gijsbert A., Florea, Bogdan I., Overkleeft, Herman S.

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Detection of Intestinal Cancer by Local, Topical Application of a Quenched Fluorescence Probe for Cysteine Cathepsins von Segal, Ehud, Prestwood, Tyler R., van der Linden, Wouter A., Carmi, Yaron, Bhattacharya, Nupur, Withana, Nimali, Verdoes, Martijn, Habtezion, Aida, Engleman, Edgar G., Bogyo, Matthew

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Design of a Highly Selective Quenched Activity-Based Probe and Its Application in Dual Color Imaging Studies of Cathepsin S Activity Localization von Oresic Bender, Kristina, Ofori, Leslie, van der Linden, Wouter A, Mock, Elliot D, Datta, Gopal K, Chowdhury, Somenath, Li, Hao, Segal, Ehud, Sanchez Lopez, Mateo, Ellman, Jonathan A, Figdor, Carl G, Bogyo, Matthew, Verdoes, Martijn

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Relative quantification of proteasome activity by activity-based protein profiling and LC-MS/MS von Li, Nan, Kuo, Chi-Lin, Paniagua, Guillem, van den Elst, Hans, Verdoes, Martijn, Willems, Lianne I, van der Linden, Wouter A, Ruben, Mark, van Genderen, Eric, Gubbens, Jacob, van Wezel, Gilles P, Overkleeft, Herman S, Florea, Bogdan I

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Incorporation of Non-natural Amino Acids Improves Cell Permeability and Potency of Specific Inhibitors of Proteasome Trypsin-like Sites von Geurink, Paul P, van der Linden, Wouter A, Mirabella, Anne C, Gallastegui, Nerea, de Bruin, Gerjan, Blom, Annet E. M, Voges, Mathias J, Mock, Elliot D, Florea, Bogdan I, van der Marel, Gijs A, Driessen, Christoph, van der Stelt, Mario, Groll, Michael, Overkleeft, Herman S, Kisselev, Alexei F

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Assessing Subunit Dependency of the Plasmodium Proteasome Using Small Molecule Inhibitors and Active Site Probes von Li, Hao, van der Linden, Wouter A, Verdoes, Martijn, Florea, Bogdan I, McAllister, Fiona E, Govindaswamy, Kavitha, Elias, Joshua E, Bhanot, Purnima, Overkleeft, Herman S, Bogyo, Matthew

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