Treatment patterns and survival outcomes of patients admitted to the intensive care unit due to immune‐related adverse events of immune checkpoint inhibitors von Lin, Lishi, Houwink, Aletta P. I., van Dieren, Jolanda M., Wolthuis, Esther K., van Thienen, Johannes V., van der Heijden, Michiel S., Haanen, John B. A. G., Beijnen, Jos H., Huitema, Alwin D. R.

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Severe Adverse Reaction to Vemurafenib in a Pregnant Woman with Metastatic Melanoma von de Haan, Jorine, van Thienen, Johannes V., Casaer, Michael, Hannivoort, Rebekka A., Van Calsteren, Kristel, van Tuyl, Minke, van Gerwen, Mathilde M., Debeer, Anne, Amant, Frédéric, Painter, Rebecca C.

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The PRO-RCC study: a long-term PROspective Renal Cell Carcinoma cohort in the Netherlands, providing an infrastructure for 'Trial within Cohorts' study designs von Yildirim, Hilin, Widdershoven, Christiaan V, Aarts, Maureen Jb, Bex, Axel, Bloemendal, Haiko J, Bochove-Overgaauw, Deirdre M, Hamberg, Paul, Herbschleb, Karin H, van der Hulle, Tom, Lagerveld, Brunolf W, van Oijen, Martijn Gh, Oosting, Sjoukje F, van Thienen, Johannes V, van der Veldt, Astrid Am, Westgeest, Hans M, Zeijdner, Evelijn E, Aben, Katja Kh, van den Hurk, Corina, Zondervan, Patricia J, Bins, Adriaan D

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Neoadjuvant versus adjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma von Blank, Christian U., Rozeman, Elisa A., Fanchi, Lorenzo F., Sikorska, Karolina, van de Wiel, Bart, Kvistborg, Pia, Krijgsman, Oscar, van den Braber, Marlous, Philips, Daisy, Broeks, Annegien, van Thienen, Johannes V., Mallo, Henk A., Adriaansz, Sandra, ter Meulen, Sylvia, Pronk, Loes M., Grijpink-Ongering, Lindsay G., Bruining, Annemarie, Gittelman, Rachel M., Warren, Sarah, van Tinteren, Harm, Peeper, Daniel S., Haanen, John B. A. G., van Akkooi, Alexander C. J., Schumacher, Ton N.

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Randomized, Double-Blind, Placebo-Controlled, Global Phase III Trial of Talimogene Laherparepvec Combined With Pembrolizumab for Advanced Melanoma von Chesney, Jason A, Ribas, Antoni, Long, Georgina V, Kirkwood, John M, Dummer, Reinhard, Puzanov, Igor, Hoeller, Christoph, Gajewski, Thomas F, Gutzmer, Ralf, Rutkowski, Piotr, Demidov, Lev, Arenberger, Petr, Shin, Sang Joon, Ferrucci, Pier Francesco, Haydon, Andrew, Hyngstrom, John, van Thienen, Johannes V, Haferkamp, Sebastian, Guilera, Josep Malvehy, Rapoport, Bernardo Leon, VanderWalde, Ari, Diede, Scott J, Anderson, James R, Treichel, Sheryl, Chan, Edward L, Bhatta, Sumita, Gansert, Jennifer, Hodi, Frank Stephen, Gogas, Helen

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Endothelial KLF2 Links Local Arterial Shear Stress Levels to the Expression of Vascular Tone-Regulating Genes von Dekker, Rob J., van Thienen, Johannes V., Rohlena, Jakub, de Jager, Saskia C., Elderkamp, Yvonne W., Seppen, Jurgen, de Vries, Carlie J.M., Biessen, Erik A.L., van Berkel, Theo J.C., Pannekoek, Hans, Horrevoets, Anton J.G.

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Identification of the optimal combination dosing schedule of neoadjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma (OpACIN-neo): a multicentre, phase 2, randomise... von Rozeman, Elisa A, Menzies, Alexander M, van Akkooi, Alexander C J, Adhikari, Chandra, Bierman, Carolien, van de Wiel, Bart A, Scolyer, Richard A, Krijgsman, Oscar, Sikorska, Karolina, Eriksson, Hanna, Broeks, Annegien, van Thienen, Johannes V, Guminski, Alexander D, Acosta, Alex Torres, ter Meulen, Sylvia, Koenen, Anne Miek, Bosch, Linda J W, Shannon, Kerwin, Pronk, Loes M, Gonzalez, Maria, Ch'ng, Sydney, Grijpink-Ongering, Lindsay G, Stretch, Jonathan, Heijmink, Stijn, van Tinteren, Harm, Haanen, John B A G, Nieweg, Omgo E, Klop, Willem M C, Zuur, Charlotte L, Saw, Robyn P M, van Houdt, Winan J, Peeper, Daniel S, Spillane, Andrew J, Hansson, Johan, Schumacher, Ton N, Long, Georgina V, Blank, Christian U

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Primary cilia sensitize endothelial cells for fluid shear stress von Hierck, Beerend P., Van der Heiden, Kim, Alkemade, Fanneke E., Van de Pas, Simone, Van Thienen, Johannes V., Groenendijk, Bianca C.W., Bax, Wilhelmina H., Van der Laarse, Arnoud, DeRuiter, Marco C., Horrevoets, Anton J.G., Poelmann, Robert E.

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Indications and Outcomes for Deferred Cytoreductive Nephrectomy Following Immune Checkpoint Inhibitor Combination Therapy: Can Systemic Therapy be Withdrawn in Patients with No Evi... von Fransen van de Putte, Elisabeth E., van den Brink, Luna, Mansour, Mohamed A., van der Mijn, Johannes C., Wilgenhof, Sofie, van Thienen, Johannes V., Haanen, John B.A.G., Boleti, Ekaterini, Powles, Thomas, Zondervan, Patricia J., Graafland, Niels M., Bex, Axel

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Avelumab treatment for patients with metastatic Merkel cell carcinoma can be safely stopped after 1 year and a PET/CT–confirmed complete response von Zijlker, Lisanne P., Levy, Sonja, Wolters, Wendy, Thienen, Johannes V., Akkooi, Alexander C. J., Tesselaar, Margot E. T.

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P-Selectin Glycoprotein Ligand-1 Is Expressed on Endothelial Cells and Mediates Monocyte Adhesion to Activated Endothelium von Martins, Paula da Costa, García-Vallejo, Juan-Jesús, van Thienen, Johannes V, Fernandez-Borja, Mar, van Gils, Janine M, Beckers, Cora, Horrevoets, Anton J, Hordijk, Peter L, Zwaginga, Jaap-Jan

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Cytoreductive nephrectomy and exposure to sunitinib – a post hoc analysis of the Immediate Surgery or Surgery After Sunitinib Malate in Treating Patients With Metastatic Kidney Can... von Abu‐Ghanem, Yasmin, Thienen, Johannes V., Blank, Christian, Aarts, Maureen J. B., Jewett, Michael, Jong, Igle Jan, Lattouf, Jean‐Baptiste, Melick, Harm H. E., Wood, Lori, Mulders, Peter, Rottey, Sylvie, Wagstaff, John, Zondervan, Patricia, Powles, Tom, Neven, Anouk, Collette, Laurence, Tombal, Bertrand, Haanen, John, Bex, Axel

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Neoadjuvant Cytoreductive Treatment With BRAF/MEK Inhibition of Prior Unresectable Regionally Advanced Melanoma to Allow Complete Surgical Resection, REDUCTOR: A Prospective, Singl... von Blankenstein, Stéphanie A., Rohaan, Maartje W., Klop, Willem Martin C., van der Hiel, Bernies, van de Wiel, Bart A., Lahaye, Max J., Adriaansz, Sandra, Sikorska, Karolina, van Tinteren, Harm, Sari, Aysegül, Grijpink-Ongering, Lindsay G., van Houdt, Winan J., Wouters, Michel W. J. M., Blank, Christian U., Wilgenhof, Sofie, van Thienen, Johannes V., van Akkooi, Alexander C. J., Haanen, John B. A. G.

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Reply to: Pioneering combination: Nivolumab and isolated limb perfusion in melanoma in-transit metastases treatment von Holmberg, Carl-Jacob, Zijlker, Lisanne P., Katsarelias, Dimitrios, Huibers, Anne E., Wouters, Michel W.J.M., Schrage, Yvonne, Reijers, Sophie J.M., van Thienen, Johannes V., Grünhagen, Dirk J., Martner, Anna, Nilsson, Jonas A., van Akkooi, Alexander C.J., Ny, Lars, van Houdt, Winan J., Olofsson Bagge, Roger

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Switch to checkpoint inhibition after targeted therapy at time of progression or during ongoing response: A retrospective single‐centre experience in patients with BRAF‐mutated mel... von Reijers, Irene L. M., Rozeman, Elisa A., Wilgenhof, Sofie, Thienen, Johannes V., Haanen, John B. A. G., Blank, Christian U.

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Primary Renal Tumour Response in Patients Treated with Nivolumab and Ipilimumab for Metastatic Renal Cell Carcinoma: Real-world Data Assessment von Meerveld-Eggink, Aafke, Graafland, Niels, Wilgenhof, Sofie, Van Thienen, Johannes V., Lalezari, Ferry, Grant, Michael, Szabados, Bernadett, Abu-Ghanem, Yasmin, Kuusk, Teele, Boleti, Ekaterini, Blank, Christian U., Haanen, John B.A.G., Powles, Thomas, Bex, Axel

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IMPemBra: a phase 2 study comparing pembrolizumab with intermittent/short-term dual MAPK pathway inhibition plus pembrolizumab in patients with melanoma harboring the BRAFV600 muta... von Rozeman, Elisa A, Versluis, Judith M, Sikorska, Karolina, Hoefsmit, Esmée P, Dimitriadis, Petros, Rao, Disha, Lacroix, Ruben, Grijpink-Ongering, Lindsay G, Lopez-Yurda, Marta, Heeres, Birthe C, van de Wiel, Bart A, Flohil, Claudie, Sari, Aysegul, Heijmink, Stijn W T P J, van den Broek, Daan, Broeks, Annegien, de Groot, Jan Willem B, Vollebergh, Marieke A, Wilgenhof, Sofie, van Thienen, Johannes V, Haanen, John B A G, Blank, Christian U

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Real-world data on tolerability and clinical response of cemiplimab in patients with advanced cutaneous squamous cell carcinoma: A retrospective, multicentre cohort study from the... von Rohaan, Maartje W., Duizer, Marleen L., Devriese, Lot A., Meerveld-Eggink, Aafke, Brandts, Willem F., van Thienen, Johannes V., Wilgenhof, Sofie, van Herpen, Carla M.L., Haanen, John B.A.G.

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Shear stress sustains atheroprotective endothelial KLF2 expression more potently than statins through mRNA stabilization von VAN THIENEN, Johannes V, FLEDDERUS, Joost O, DEKKER, Rob J, ROHLENA, Jakub, VAN IJZENDOOM, Gerben A, KOOTSTRA, Neeltje A, PANNEKOEK, Hans, HORREVOETS, Anton J. G

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Tumor-Infiltrating Lymphocyte Therapy or Ipilimumab in Advanced Melanoma von Rohaan, Maartje W., Borch, Troels H., van den Berg, Joost H., Met, Özcan, Kessels, Rob, Geukes Foppen, Marnix H., Stoltenborg Granhøj, Joachim, Nuijen, Bastiaan, Nijenhuis, Cynthia, Jedema, Inge, van Zon, Maaike, Scheij, Saskia, Beijnen, Jos H., Hansen, Marten, Voermans, Carlijn, Noringriis, Inge M., Monberg, Tine J., Holmstroem, Rikke B., Wever, Lidwina D.V., van Dijk, Marloes, Grijpink-Ongering, Lindsay G., Valkenet, Ludy H.M., Torres Acosta, Alejandro, Karger, Matthias, Borgers, Jessica S.W., ten Ham, Renske M.T., Retèl, Valesca P., van Harten, Wim H., Lalezari, Ferry, van Tinteren, Harm, van der Veldt, Astrid A.M., Hospers, Geke A.P., Stevense-den Boer, Marion A.M., Suijkerbuijk, Karijn P.M., Aarts, Maureen J.B., Piersma, Djura, van den Eertwegh, Alfons J.M., de Groot, Jan-Willem B., Vreugdenhil, Gerard, Kapiteijn, Ellen, Boers-Sonderen, Marye J., Fiets, W. Edward, van den Berkmortel, Franchette W.P.J., Ellebaek, Eva, Hölmich, Lisbet R., van Akkooi, Alexander C.J., van Houdt, Winan J., Wouters, Michel W.J.M., van Thienen, Johannes V., Blank, Christian U., Meerveld-Eggink, Aafke, Klobuch, Sebastian, Wilgenhof, Sofie, Schumacher, Ton N., Donia, Marco, Svane, Inge Marie, Haanen, John B.A.G.

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