Polycomb silencers control cell fate, development and cancer von van Lohuizen, Maarten, Sparmann, Anke

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Chromatin Position Effects Assayed by Thousands of Reporters Integrated in Parallel von Akhtar, Waseem, de Jong, Johann, Pindyurin, Alexey V., Pagie, Ludo, Meuleman, Wouter, de Ridder, Jeroen, Berns, Anton, Wessels, Lodewyk F.A., van Lohuizen, Maarten, van Steensel, Bas

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Multiplexed Cas9 targeting reveals genomic location effects and gRNA-based staggered breaks influencing mutation efficiency von Gisler, Santiago, Gonçalves, Joana P., Akhtar, Waseem, de Jong, Johann, Pindyurin, Alexey V., Wessels, Lodewyk F. A., van Lohuizen, Maarten

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Functional Crosstalk between Bmi1 and MLL/Hoxa9 Axis in Establishment of Normal Hematopoietic and Leukemic Stem Cells von Smith, Lan-Lan, Yeung, Jenny, Zeisig, Bernd B., Popov, Nikolay, Huijbers, Ivo, Barnes, Josephine, Wilson, Amanda J., Taskesen, Erdogan, Delwel, Ruud, Gil, Jesús, Van Lohuizen, Maarten, So, Chi Wai Eric

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Prolonged Ezh2 Depletion in Glioblastoma Causes a Robust Switch in Cell Fate Resulting in Tumor Progression von de Vries, Nienke A., Hulsman, Danielle, Akhtar, Waseem, de Jong, Johann, Miles, Denise C., Blom, Marleen, van Tellingen, Olaf, Jonkers, Jos, van Lohuizen, Maarten

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Stem cell regulation by polycomb repressors: postponing commitment von Pietersen, Alexandra M, van Lohuizen, Maarten

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In Vivo RNAi Screen for BMI1 Targets Identifies TGF-β/BMP-ER Stress Pathways as Key Regulators of Neural- and Malignant Glioma-Stem Cell Homeostasis von Gargiulo, Gaetano, Cesaroni, Matteo, Serresi, Michela, de Vries, Nienke, Hulsman, Danielle, Bruggeman, Sophia W., Lancini, Cesare, van Lohuizen, Maarten

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Molecular Maps of the Reorganization of Genome-Nuclear Lamina Interactions during Differentiation von Peric-Hupkes, Daan, Meuleman, Wouter, Pagie, Ludo, Bruggeman, Sophia W.M., Solovei, Irina, Brugman, Wim, Gräf, Stefan, Flicek, Paul, Kerkhoven, Ron M., van Lohuizen, Maarten, Reinders, Marcel, Wessels, Lodewyk, van Steensel, Bas

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Epigenetics and cancer von Lund, Anders H, van Lohuizen, Maarten

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Functional anatomy of polycomb and trithorax chromatin landscapes in Drosophila embryos von Schuettengruber, Bernd, Ganapathi, Mythily, Leblanc, Benjamin, Portoso, Manuela, Jaschek, Rami, Tolhuis, Bas, van Lohuizen, Maarten, Tanay, Amos, Cavalli, Giacomo

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BMI1 Is Recruited to DNA Breaks and Contributes to DNA Damage-Induced H2A Ubiquitination and Repair von Ginjala, Vasudeva, Nacerddine, Karim, Kulkarni, Atul, Oza, Jay, Hill, Sarah J., Yao, Ming, Citterio, Elisabetta, van Lohuizen, Maarten, Ganesan, Shridar

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TRIM28 Is an Epigenetic Barrier to Induced Pluripotent Stem Cell Reprogramming von Miles, Denise Catherine, de Vries, Nienke Alexandra, Gisler, Santiago, Lieftink, Cor, Akhtar, Waseem, Gogola, Ewa, Pawlitzky, Inka, Hulsman, Danielle, Tanger, Ellen, Koppens, Martijn, Beijersbergen, Roderick Leonardus, van Lohuizen, Maarten

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Structure and E3-ligase activity of the Ring-Ring complex of Polycomb proteins Bmi1 and Ring1b von Buchwald, Gretel, van der Stoop, Petra, Weichenrieder, Oliver, Perrakis, Anastassis, van Lohuizen, Maarten, Sixma, Titia K

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PRC1 coordinates timing of sexual differentiation of female primordial germ cells von Yokobayashi, Shihori, Liang, Ching-Yeu, Kohler, Hubertus, Nestorov, Peter, Liu, Zichuan, Vidal, Miguel, van Lohuizen, Maarten, Roloff, Tim C., Peters, Antoine H. F. M.

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Combined deletion of Bap1, Nf2, and Cdkn2ab causes rapid onset of malignant mesothelioma in mice von Badhai, Jitendra, Pandey, Gaurav Kumar, Song, Ji-Ying, Krijgsman, Oscar, Bhaskaran, Rajith, Chandrasekaran, Gayathri, Kwon, Min-chul, Bombardelli, Lorenzo, Monkhorst, Kim, Grasso, Cristoforo, Zevenhoven, John, van der Vliet, Jan, Cozijnsen, Miranda, Krimpenfort, Paul, Peeper, Daniel, van Lohuizen, Maarten, Berns, Anton

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Interactions among Polycomb domains are guided by chromosome architecture von Tolhuis, Bas, Blom, Marleen, Kerkhoven, Ron M, Pagie, Ludo, Teunissen, Hans, Nieuwland, Marja, Simonis, Marieke, de Laat, Wouter, van Lohuizen, Maarten, van Steensel, Bas

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Deletion of Polycomb Repressive Complex 2 From Mouse Intestine Causes Loss of Stem Cells von Koppens, Martijn A.J, Bounova, Gergana, Gargiulo, Gaetano, Tanger, Ellen, Janssen, Hans, Cornelissen-Steijger, Paulien, Blom, Marleen, Song, Ji-Ying, Wessels, Lodewyk F.A, van Lohuizen, Maarten

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Genome-wide profiling of PRC1 and PRC2 Polycomb chromatin binding in Drosophila melanogaster von van Steensel, Bas, van Lohuizen, Maarten, Tolhuis, Bas, Muijrers, Inhua, de Wit, Elzo, Teunissen, Hans, Talhout, Wendy

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Polycomb Group Proteins Ezh2 and Rnf2 Direct Genomic Contraction and Imprinted Repression in Early Mouse Embryos von Terranova, Rémi, Yokobayashi, Shihori, Stadler, Michael B., Otte, Arie P., van Lohuizen, Maarten, Orkin, Stuart H., Peters, Antoine H.F.M.

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A genome-wide enrichment screen identifies NUMA1-loss as a resistance mechanism against mitotic cell-death induced by BMI1 inhibition von Gisler, Santiago, Maia, Ana Rita R., Chandrasekaran, Gayathri, Kopparam, Jawahar, van Lohuizen, Maarten

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