Therapeutic hFIX Activity Achieved after Single AAV5-hFIX Treatment in Hemophilia B Patients and NHPs with Pre-existing Anti-AAV5 NABs von Majowicz, Anna, Nijmeijer, Bart, Lampen, Margit H., Spronck, Lisa, de Haan, Martin, Petry, Harald, van Deventer, Sander J., Meyer, Christian, Tangelder, Marco, Ferreira, Valerie

Volltext

Infliximab but not etanercept induces apoptosis in lamina propria T-lymphocytes from patients with Crohn’s disease von Van den Brande, Jan M.H, Braat, Henri, van den Brink, Gijs R, Versteeg, Henri H, Bauer, Christiaan A, Hoedemaeker, Inge, van Montfrans, Catherine, Hommes, Daan W, Peppelenbosch, Maikel P, van Deventer, Sander J.H

Volltext

Treatment and Prevention of Staphylococcus epidermidis Experimental Biomaterial-Associated Infection by Bactericidal Peptide 2 von KWAKMAN, Paulus H. S, TE VELDE, Anje A, VANDENBROUCKE -GRAULS, Christina M. J. E, VAN DEVENTER, Sander J. H, ZAAT, Sebastian A. J

Volltext

Dichotomy between Lactobacillus rhamnosus and Klebsiella pneumoniae on dendritic cell phenotype and function von BRAAT, Henri, DE JONG, Esther C, VAN DEN BRANDE, Jan M. H, KAPSENBERG, Martien L, PEPPELENBOSCH, Maikel P, VAN TOL, Eric A. F, VAN DEVENTER, Sander J. H

Volltext

Adenosine triphosphate-binding cassette transporter genes up-regulation in untreated hepatocellular carcinoma is mediated by cellular microRNAs von Borel, Florie, Han, Ruiqi, Visser, Allerdien, Petry, Harald, van Deventer, Sander J.H., Jansen, Peter L.M., Konstantinova, Pavlina

Volltext

Distribution and Kinetics of Lipoprotein-Bound Lipoteichoic Acid von LEVELS, Johannes H. M, ABRAHAM, Philip R, VAN BARREVELD, Erik P, MEIJERS, Joost C. M, VAN DEVENTER, Sander J. H

Volltext

Potent and sustained huntingtin lowering via AAV5 encoding miRNA preserves striatal volume and cognitive function in a humanized mouse model of Huntington disease von Caron, Nicholas S, Southwell, Amber L, Brouwers, Cynthia C, Cengio, Louisa Dal, Xie, Yuanyun, Black, Hailey Findlay, Anderson, Lisa M, Ko, Seunghyun, Zhu, Xiang, van Deventer, Sander J, Evers, Melvin M, Konstantinova, Pavlina, Hayden, Michael R

Volltext

CpG Oligodeoxynucleotides Enhance Host Defense during Murine Tuberculosis von JUFFERMANS, Nicole P, LEEMANS, Jaklien C, FLORQUIN, Sandrine, VERBON, Annelies, KOLK, Arend H, SPEELMAN, Peter, VAN DEVENTER, Sander J. H, VAN DER POLL, Tom

Volltext

Cholesterol ester transfer protein inhibition by TA-8995 in patients with mild dyslipidaemia (TULIP): a randomised, double-blind, placebo-controlled phase 2 trial von Hovingh, G Kees, Dr, Kastelein, John J P, Prof, van Deventer, Sander J H, Prof, Round, Patrick, Ford, John, Saleheen, Danish, Rader, Daniel J, Prof, Brewer, H Bryan, Prof, Barter, Philip J, Prof

Volltext

AAV5-miHTT Gene Therapy Demonstrates Broad Distribution and Strong Human Mutant Huntingtin Lowering in a Huntington’s Disease Minipig Model von Evers, Melvin M., Miniarikova, Jana, Juhas, Stefan, Vallès, Astrid, Bohuslavova, Bozena, Juhasova, Jana, Skalnikova, Helena Kupcova, Vodicka, Petr, Valekova, Ivona, Brouwers, Cynthia, Blits, Bas, Lubelski, Jacek, Kovarova, Hana, Ellederova, Zdenka, van Deventer, Sander J., Petry, Harald, Motlik, Jan, Konstantinova, Pavlina

Volltext

Infliximab Treatment for Crohn's Disease: One-Year Experience in a Dutch Academic Hospital von Hommes, Daan W., van de Heisteeg, Brenda H., van der Spek, Mirjam, Bartelsman, Joep F. W. M., van Deventer, Sander J. H.

Volltext

Longitudinal Assessment of Lipoprotein(a) Levels in Perinatally HIV-Infected Children and Adolescents von van Genderen, Jason G, Van den Hof, Malon, de Boer, Claudia G, Jansen, Hans P G, van Deventer, Sander J H, Tsimikas, Sotirios, Witztum, Joseph L, Kastelein, John J P, Pajkrt, Dasja

Volltext

NF-kappaB, p38 MAPK and JNK are highly expressed and active in the stroma of human colonic adenomatous polyps von HARDWICK, James C. H, VAN DEN BRINK, Gijs R, OFFERHAUS, G. J, VAN DEVENTER, Sander J. H, PEPPELENBOSCH, Maikel P

Volltext

Factor VIIa/Tissue Factor-induced Signaling via Activation of Src-like Kinases, Phosphatidylinositol 3-Kinase, and Rac von Versteeg, H H, Hoedemaeker, I, Diks, S H, Stam, J C, Spaargaren, M, van Bergen En Henegouwen, P M, van Deventer, S J, Peppelenbosch, M P

Volltext

Targeting RNA-Mediated Toxicity in C9orf72 ALS and/or FTD by RNAi-Based Gene Therapy von Martier, Raygene, Liefhebber, Jolanda M., García-Osta, Ana, Miniarikova, Jana, Cuadrado-Tejedor, Mar, Espelosin, Maria, Ursua, Susana, Petry, Harald, van Deventer, Sander J., Evers, Melvin M., Konstantinova, Pavlina

Volltext

Recurrent Venous Thrombosis and Markers of Inflammation von van Aken, Benien E., den Heijer, Martin, Bos, Gerard M. J., van Deventer, Sander J. H., Reitsma, Pieter H.

Volltext

Anti-Inflammatory Effects of a p38 Mitogen-Activated Protein Kinase Inhibitor During Human Endotoxemia von Branger, Judith, van den Blink, Bernt, Weijer, Sebastiaan, Madwed, Jeffrey, Bos, Carina L, Gupta, Abhya, Yong, Chan-Loi, Polmar, Stephen H, Olszyna, Dariusz P, Hack, C. Erik, van Deventer, Sander J. H, Peppelenbosch, Maikel P, van der Poll, Tom

Volltext

Mast cell degranulation during abdominal surgery initiates postoperative ileus in mice von de Jonge, Wouter J, The, Frans O, van der Coelen, Dennis, Bennink, Roelof J, Reitsma, Pieter H, van Deventer, Sander J, van den Wijngaard, René M, Boeckxstaens, Guy E

Volltext

Artificial MicroRNAs Targeting C9orf72 Can Reduce Accumulation of Intra-nuclear Transcripts in ALS and FTD Patients von Martier, Raygene, Liefhebber, Jolanda M., Miniarikova, Jana, van der Zon, Tom, Snapper, Jolanda, Kolder, Iris, Petry, Harald, van Deventer, Sander J., Evers, Melvin M., Konstantinova, Pavlina

Volltext

AAV5-miHTT Gene Therapy Demonstrates Sustained Huntingtin Lowering and Functional Improvement in Huntington Disease Mouse Models von Spronck, Elisabeth A., Brouwers, Cynthia C., Vallès, Astrid, de Haan, Martin, Petry, Harald, van Deventer, Sander J., Konstantinova, Pavlina, Evers, Melvin M.

Volltext