Desensitization of soluble guanylyl cyclase, the NO receptor, by S-nitrosylation von Sayed, Nazish, Baskaran, Padmamalini, Ma, Xiaolei, van den Akker, Focco, Beuve, Annie

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Structural analysis of the boronic acid beta-lactamase inhibitor vaborbactam binding to Pseudomonas aeruginosa penicillin-binding protein 3 von Kumar, Vijay, Viviani, Samantha L., Ismail, Jeeda, Agarwal, Shreya, Bonomo, Robert A., van den Akker, Focco

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NO and CO differentially activate soluble guanylyl cyclase via a heme pivot-bend mechanism von Ma, Xiaolei, Sayed, Nazish, Beuve, Annie, van den Akker, Focco

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Inhibition of Klebsiella β-Lactamases (SHV-1 and KPC-2) by Avibactam: A Structural Study von Krishnan, Nikhil P, Nguyen, Nhu Q, Papp-Wallace, Krisztina M, Bonomo, Robert A, van den Akker, Focco

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Structural Characterization of Diazabicyclooctane beta-Lactam "Enhancers" in Complex with Penicillin-Binding Proteins PBP2 and PBP3 of Pseudomonas aeruginosa von Rajavel, Malligarjunan, Kumar, Vijay, Ha Nguyen, Wyatt, Jacob, Marshall, Steven H., Papp-Wallace, Krisztina M., Deshpande, Prasad, Bhavsar, Satish, Yeole, Ravindra, Bhagwat, Sachin, Patel, Mahesh, Bonomo, Robert A., van den Akker, Focco

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PAS-mediated Dimerization of Soluble Guanylyl Cyclase Revealed by Signal Transduction Histidine Kinase Domain Crystal Structure von Ma, Xiaolei, Sayed, Nazish, Baskaran, Padmamalini, Beuve, Annie, van den Akker, Focco

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Crystal structure of the signaling helix coiled-coil domain of the β1 subunit of the soluble guanylyl cyclase von Ma, Xiaolei, Beuve, Annie, van den Akker, Focco

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Identification of residues in the heme domain of soluble guanylyl cyclase that are important for basal and stimulated catalytic activity von Baskaran, Padmamalini, Heckler, Erin J, van den Akker, Focco, Beuve, Annie

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Crystal structure of cholera toxin B-pentamer bound to receptor GM1 pentasaccharide von Merritt, E. A, Sarfaty, S, van den Akker, F, L'Hoir, C, Martial, Joseph, Hol, W. G

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Penam sulfones and β-lactamase inhibition: SA2-13 and the importance of the C2 side chain length and composition von Rodkey, Elizabeth A, Winkler, Marisa L, Bethel, Christopher R, Pagadala, Sundar Ram Reddy, Buynak, John D, Bonomo, Robert A, van den Akker, Focco

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Structures of SHV-1 β-lactamase with penem and penam sulfone inhibitors that form cyclic intermediates stabilized by carbonyl conjugation von Ke, Wei, Pattanaik, Priyaranjan, Bethel, Christopher R, Sheri, Anjaneyulu, Buynak, John D, Bonomo, Robert A, van den Akker, Focco

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Structure of the dimerized hormone-binding domain of a guanylyl- cyclase-coupled receptor von Miyagi, Masaru, van den Akker, Focco, Zhang, Xiaolun, Yee, Vivien C, Huo, Xuewen, Misono, Kunio S

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Structural analysis of the boronic acid β-lactamase inhibitor vaborbactam binding to Pseudomonas aeruginosa penicillin-binding protein 3 von Vijay Kumar, Samantha L Viviani, Jeeda Ismail, Shreya Agarwal, Robert A Bonomo, Focco van den Akker

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Identification of new inhibitors of soluble guanylyl cyclase activity von Vijayraghavan, Jagamya, Akker, Focco van den

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The Novel β-Lactamase Inhibitor, ETX-2514, in Combination with Sulbactam Effectively Inhibits Acinetobacter baumannii von Barnes, Melissa D, Bethel, Christopher R, Rutter, Joseph D, Akker, Focco Van Den, Papp-Wallace, Krisztina M, Bonomo, Robert A

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Structural analysis of the boronic acid [beta]-lactamase inhibitor vaborbactam binding to Pseudomonas aeruginosa penicillin-binding protein 3 von Kumar, Vijay, Viviani, Samantha L, Ismail, Jeeda, Agarwal, Shreya, Bonomo, Robert A, van den Akker, Focco

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Adenovirus E1A Down-regulates LMP2 Transcription by Interfering with the Binding of Stat1 to IRF1 von Chatterjee-Kishore, Moitreyee, van den Akker, Focco, Stark, George R.

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Strategic Approaches to Overcome Resistance against Gram-Negative Pathogens Using β‑Lactamase Inhibitors and β‑Lactam Enhancers: Activity of Three Novel Diazabicyclooctanes WCK 515... von Papp-Wallace, Krisztina M, Nguyen, Nhu Q, Jacobs, Michael R, Bethel, Christopher R, Barnes, Melissa D, Kumar, Vijay, Bajaksouzian, Saralee, Rudin, Susan D, Rather, Philip N, Bhavsar, Satish, Ravikumar, Tadiparthi, Deshpande, Prasad K, Patil, Vijay, Yeole, Ravindra, Bhagwat, Sachin S, Patel, Mahesh V, van den Akker, Focco, Bonomo, Robert A

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Molecular recognition of S-nitrosothiol substrate by its cognate protein denitrosylase von Stomberski, Colin T., Zhou, Hua-Lin, Wang, Liwen, van den Akker, Focco, Stamler, Jonathan S.

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Turnover Chemistry and Structural Characterization of the Cj0843c Lytic Transglycosylase of Campylobacter jejuni von Kumar, Vijay, Mathure, Snigdha A, Lee, Mijoon, Boorman, Jacob, Zeng, Ximin, Lin, Jun, Hesek, Dusan, Lastochkin, Elena, Mobashery, Shahriar, van den Akker, Focco

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