Mechanism-based screen for G1/S checkpoint activators identifies a selective activator of EIF2AK3/PERK signalling von Stockwell, Simon R, Platt, Georgina, Barrie, S Elaine, Zoumpoulidou, Georgia, Te Poele, Robert H, Aherne, G Wynne, Wilson, Stuart C, Sheldrake, Peter, McDonald, Edward, Venet, Mathilde, Soudy, Christelle, Elustondo, Frédéric, Rigoreau, Laurent, Blagg, Julian, Workman, Paul, Garrett, Michelle D, Mittnacht, Sibylle

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The Cyclin-Dependent Kinase Inhibitor Seliciclib (R-roscovitine; CYC202) Decreases the Expression of Mitotic Control Genes and Prevents Entry into Mitosis von Whittaker, Steven R., te Poele, Robert H., Chan, Florence, Linardopoulos, Spiros, Walton, Michael I., Garrett, Michelle D., Workman, Paul

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DNA damage is able to induce senescence in tumor cells in vitro and in vivo von TE POELE, Robert H, OKOROKOV, Andrei L, JARDINE, Lesley, CUMMINGS, Jeffrey, JOEL, Simon P

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RNA synthesis block by 5, 6-dichloro-1-beta-D-ribofuranosylbenzimidazole (DRB) triggers p53-dependent apoptosis in human colon carcinoma cells von te Poele, R H, Okorokov, A L, Joel, S P

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Schedule-dependent cytotoxicity of SN-38 in p53 wild-type and mutant colon adenocarcinoma cell lines von Poele, R H te, Joel, S P

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283 SPECT/CT EVALUATION OF HIGH PRECISION HEART IRRADIATION IN SMALL ANIMALS von Gasparini, A, Te Poele, H, Zijp, L, Stewart, F, Sonke, J.J

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AT13148 Is a Novel, Oral Multi-AGC Kinase Inhibitor with Potent Pharmacodynamic and Antitumor Activity von YAP, Timothy A, WALTON, Mike I, HEINZMANN, Kathrin, JONES, Paul S, FELTELL, Ruth E, REULE, Matthias, WOODHEAD, Steven J, DAVIES, Thomas G, LYONS, John F, RAYNAUD, Florence I, ECCLES, Suzanne A, WORKMAN, Paul, GRIMSHAW, Kyla M, THOMPSON, Neil T, GARRETT, Michelle D, TE POELE, Robert H, EVE, Paul D, VALENTI, Melanie R, DE HAVEN BRANDON, Alexis K, MARTINS, Vanessa, ZETTERLUND, Anna, HEATON, Simon P

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PD-0239 PRE-CLINICAL IMPLEMENTATION OF A SMALL ANIMAL IMAGE-GUIDED IRRADIATOR von Gasparini, A, de Gooijer, M.C, te Poele, H, Stewart, F, van Tellingen, O, Sonke, J.J

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Histone Deacetylase Inhibition Increases Levels of Choline Kinase α and Phosphocholine Facilitating Noninvasive Imaging in Human Cancers von BELOUECHE-BABARI, Mounia, ARUNAN, Vaitha, LEACH, Martin O, CHUNG, Yuen-Li, TROY, Helen, TE POELE, Robert H, WONG TE FONG, Anne-Christine, ELIZABETH JACKSON, L, PAYNE, Geoffrey S, GRIFFITHS, John R, JUDSON, Ian R, WORKMAN, Paul

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Correlation of Overall Survival With Gene Expression Profiles in a Prospective Study of Resectable Esophageal Cancer von Rao, Sheela, Welsh, Lyndsey, Cunningham, David, te-Poele, Robert H, Benson, Martin, Norman, Andrew, Saffery, Claire, Giddings, Ian, Workman, Paul, Clarke, Paul A

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In Vitro and In Vivo Expression of Endothelial von Willebrand Factor and Leukocyte Accumulation after Fractionated Irradiation von van Kleef, Ellen, Verheij, Marcel, Poele, Hans te, Oussoren, Yvonne, Dewit, Luc, Stewart, Fiona

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Abstract 2998: Molecular and cellular effects of individual and combinatorial silencing of HSP90 paralogs von Powers, Marissa V., Te Poele, Robert H., Murphy, Ravindhi L., de Billy, Emmanuel, Clarke, Paul A., Workman, Paul

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Re: Loss of DNA Mismatch Repair: Effects on the Rate of Mutation to Drug Resistance von Liu, Wai M., te Poele, Robert H., Joel, Simon P.

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Histone deacetylase inhibition increases levels of choline kinase alpha and phosphocholine facilitating non-invasive imaging in human cancers von Beloueche-Babari, Mounia, Arunan, Vaitha, Troy, Helen, te Poele, Robert H, Fong, Anne-Christine Wong Te, Jackson, L Elizabeth, Payne, Geoffrey S, Griffiths, John R, Judson, Ian R, Workman, Paul, Leach, Martin O, Chung, Yuen-Li

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Abstract 928: The novel clinical candidate AT13148 is an oral multi-AGC kinase inhibitor with potent pharmacodynamic and antitumor activity and demonstrates a mechanism of action d... von Yap, Timothy A., Walton, Michael I., Grimshaw, Kyla M., Poele, Robert H. te, Eve, Paul D., Valenti, Melanie R., de Haven Brandon, Alexis K., Martins, Vanessa, Zetterlund, Anna, Heaton, Simon P., Heinzmann, Kathrin, Jones, Paul S., Feltell, Ruth E., Reule, Matthias, Woodhead, Steven J., Davies, Thomas G., Lyons, John F., Raynaud, Florence I., Eccles, Suzanne A., Workman, Paul, Thompson, Neil T., Garrett, Michelle D.

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Niacin induces PPARgamma expression and transcriptional activation in macrophages via HM74 and HM74a-mediated induction of prostaglandin synthesis pathways von Knowles, Helen J, te Poele, Robert H, Te Poole, Robert, Workman, Paul, Harris, Adrian L

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Re: Loss of DNA mismatch repair: Effects on the rate of mutation to drug resistance / Response von Liu, Wai M, te Poele, Robert H, Joel, Simon P, Maida M de las Alas

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An Efficient System for Active Bovine Pancreatic Ribonuclease Expression in Escherichia coli von Okorokov, A.L., Panov, K.I., Poele, R.H.T., Breukelman, H.J., Furia, A., Karpeisky, M.Y., Beintema, J.J.

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Mechanism-based screen for G1/S checkpoint activators identifies a selective activator of EIF2AK3/PERK signalling von Stockwell, SR, Platt, G, Barrie, SE, Zoumpoulidou, G, Te Poele, RH, Aherne, GW, Wilson, SC, Sheldrake, P, McDonald, E, Venet, M, Soudy, C, Elustondo, F, Rigoreau, L, Blagg, J, Workman, P, Garrett, MD, Mittnacht, S

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Influence of acetylsalicylic acid on development of radiation-induced nephropathy von VAN KLEEF, E. M, TE POELE, J. A. M, OUSSOREN, Y. G, VAN DER WAL, A, DEWIT, L. G. H, STEWART, F. A

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