A Plaque-Specific Antibody Clears Existing β-amyloid Plaques in Alzheimer's Disease Mice von DeMattos, Ronald B., Lu, Jirong, Tang, Ying, Racke, Margaret M., DeLong, Cindy A., Tzaferis, John A., Hole, Justin T., Forster, Beth M., McDonnell, Peter C., Liu, Feng, Kinley, Robert D., Jordan, William H., Hutton, Michael L.

Volltext

LY2456302 is a novel, potent, orally-bioavailable small molecule kappa-selective antagonist with activity in animal models predictive of efficacy in mood and addictive disorders von Rorick-Kehn, Linda M., Witkin, Jeffrey M., Statnick, Michael A., Eberle, Elizabeth L., McKinzie, Jamie H., Kahl, Steven D., Forster, Beth M., Wong, Conrad J., Li, Xia, Crile, Robert S., Shaw, David B., Sahr, Allison E., Adams, Benjamin L., Quimby, Steven J., Diaz, Nuria, Jimenez, Alma, Pedregal, Concepcion, Mitch, Charles H., Knopp, Kelly L., Anderson, Wesley H., Cramer, Jeffrey W., McKinzie, David L.

Volltext

Broad spectrum efficacy with LY2969822, an oral prodrug of metabotropic glutamate 2/3 receptor agonist LY2934747, in rodent pain models von Johnson, Michael P, Muhlhauser, Mark A, Nisenbaum, Eric S, Simmons, Rosa M A, Forster, Beth M, Knopp, Kelly L, Yang, Lijuan, Morrow, Denise, Li, Dominic L, Kennedy, Jeffrey D, Swanson, Steven, Monn, James A

Volltext

A Plaque-Specific Antibody Clears Existing [beta]-amyloid Plaques in Alzheimer's Disease Mice von DeMattos, Ronald B, Lu, Jirong, Tang, Ying, Racke, Margaret M, DeLong, Cindy A, Tzaferis, John A, Hole, Justin T, ster, Beth M, McDonnell, Peter C, Liu, Feng, Kinley, Robert D, Jordan, William H, Hutton, Michael L

Volltext