IL-22-dependent dysbiosis and mononuclear phagocyte depletion contribute to steroid-resistant gut graft-versus-host disease in mice von Song, Qingxiao, Wang, Xiaoning, Wu, Xiwei, Kang, Tae Hyuk, Qin, Hanjun, Zhao, Dongchang, Jenq, Robert R., van den Brink, Marcel R. M., Riggs, Arthur D., Martin, Paul J., Chen, Yuan-Zhong, Zeng, Defu

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Steroid-Refractory Gut Graft-Versus-Host Disease: What We Have Learned From Basic Immunology and Experimental Mouse Model von Song, Qingxiao, Nasri, Ubaydah, Zeng, Defu

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Antibodies from donor B cells perpetuate cutaneous chronic graft-versus-host disease in mice von Jin, Hua, Ni, Xiong, Deng, Ruishu, Song, Qingxiao, Young, James, Cassady, Kaniel, Zhang, Mingfeng, Forman, Stephen, Martin, Paul J., Liu, Qifa, Zeng, Defu

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Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease von Deng, Ruishu, Hurtz, Christian, Song, Qingxiao, Yue, Chanyu, Xiao, Gang, Yu, Hua, Wu, Xiwei, Muschen, Markus, Forman, Stephen, Martin, Paul J., Zeng, Defu

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Murine Models Provide New Insights Into Pathogenesis of Chronic Graft- Versus -Host Disease in Humans von Song, Qingxiao, Kong, Xiaohui, Martin, Paul J, Zeng, Defu

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Retention of Donor T Cells in Lymphohematopoietic Tissue and Augmentation of Tissue PD-L1 Protection for Prevention of GVHD While Preserving GVL Activity von Song, Qingxiao, Nasri, Ubaydah, Nakamura, Ryotaro, Martin, Paul J, Zeng, Defu

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Donor T cell STAT3 deficiency enables tissue PD-L1-dependent prevention of graft-versus-host disease while preserving graft-versus-leukemia activity von Li, Qinjian, Wang, Xiaoqi, Song, Qingxiao, Yang, Shijie, Wu, Xiwei, Yang, Dongyun, Marié, Isabelle J, Qin, Hanjun, Zheng, Moqian, Nasri, Ubaydah, Kong, Xiaohui, Wang, Bixin, Lizhar, Elizabeth, Cassady, Kaniel, Tompkins, Josh, Levy, David, Martin, Paul J, Zhang, Xi, Zeng, Defu

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Recent advances and research progress regarding monoclonal antibodies for chronic graft-versus-host disease von Huang, Shiqin, Cheng, Xianjing, Yang, Guancui, Huang, Ruihao, Feng, Yimei, Zeng, Lingyu, Wu, Tao, Song, Qingxiao, Wang, Xiaoqi, Zhang, Xi

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Advances in hematopoietic stem cell transplantation for autoimmune diseases von Xu, Yuxi, Wang, Xiaoqi, Hu, Ziyi, Huang, Ruihao, Yang, Guancui, Wang, Rui, Yang, Shijie, Guo, Liyan, Song, Qingxiao, Wei, Jin, Zhang, Xi

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Anti-CD3 Antibody Ameliorates Transfusion-Associated Graft-Versus-Host Disease in a Chemotherapy-Based Mouse Model With Busulfan and Fludarabine von Li, Xiaofan, Song, Qingxiao, Hu1, Wanyu, Wan, Bo, Huang, Qinghua, Li, Qing

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Blockade of PD-L1/CD80 Interactions Augments Function of Activated Donor T Cells Results in Augmenting Gvhd Induced By Donor Naïve CD8 + t Cells and GVL Effect Mediated By Donor Me... von Song, Qingxiao, Zhang, Yuankun, Cassady, Kaniel, Li, Qinjian, Martin, Paul J., Zeng, Defu

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PD-L1 interacts with CD80 to regulate graft-versus-leukemia activity of donor CD8+ T cells von Ni, Xiong, Song, Qingxiao, Cassady, Kaniel, Deng, Ruishu, Jin, Hua, Zhang, Mingfeng, Dong, Haidong, Forman, Stephen, Martin, Paul J, Chen, Yuan-Zhong, Wang, Jianmin, Zeng, Defu

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Targeting Intestinal Epithelial Ceacam1 Expands Peripheral Tregs and Prevents Steroid-Refractory Acute Gut Graft-Versus-Host Disease von Song, Qingxiao, Zheng, Moqian, Li, Qinjian, Wu, Xiwei, Qin, Hanjun, Kang, Tae Hyuk, Hong, Yaqun, Wang, Bixin, Kujawski, Maciej, Shively, Jack, Nakamura, Ryotaro, Martin, Paul J, Zeng, Defu

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Tolerogenic anti–IL-2 mAb prevents graft-versus-host disease while preserving strong graft-versus-leukemia activity von Song, Qingxiao, Wang, Xiaoning, Wu, Xiwei, Qin, Hanjun, Li, Yingfei, Riggs, Arthur D., Martin, Paul J., Chen, Yuan-Zhong, Zeng, Defu

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Combination Therapy of Allogeneic HSCT and In Vivo Activated iNKT Cells Prevents Acute Gvhd While Augmenting GVL Effect von Zeng, Samuel, Song, Qingxiao, Tang, Shanshan, Wang, Xi, Wang, Yuchen, Zeng, Defu, Yang, Lili

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Expansion of Th/Tc17 T Cells and Loss of CX3CR1+ Macrophages Play a Critical Role in the Pathogenesis of Steroid-Refractory Acute Intestinal Gvhd von Song, Qingxiao, Wang, Xiaoning, Martin, Paul J, Chen, Yuanzhong, Zeng, Defu

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Donor programmed cell death 1 ligand 1 is required for organ transplant tolerance in major histocompatibility complex-mismatched mixed chimeras although programmed cell death 1 lig... von Huang, Yaxun, Wu, Xiwei, Tang, Shanshan, Wu, Huiqing, Nasri, Ubaydah, Qin, Qi, Song, Qingxiao, Wang, Bixin, Tao, Hansen, Chong, Anita S, Riggs, Arthur D, Zeng, Defu

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Blockade of trans PD-L1 interaction with CD80 augments antitumor immunity von Zhang, Yuankun, Song, Qingxiao, Cassady, Kaniel, Lee, Michael, Tang, Haidong, Zheng, Moqian, Wang, Bixin, Schones, Dustin E, Fu, Yang-Xin, Riggs, Arthur D, Martin, Paul J, Feng, Ru, Zeng, Defu

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Neutralization of IL-2 prevents acute GVHD while preserving GVL activity via regulating PD-L1/PD-1 signaling von Song, Qingxiao, Wang, Xiaoning, Martin, Paul J., Chen, Yuanzhong, Zeng, Defu

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Abstract 3180: Blockade of PD-L1 interaction with CD80 in trans augments anti-tumor immunity by increasing NOS2 in tumor-associated macrophages von Zhang, Yuankun, Song, Qingxiao, Lee, Michael, Tang, Haidong, Cassady, Kaniel, Fu, Yang-Xin, Schones, Dustin E., Riggs, Arthur, Feng, Ru, Zeng, Defu

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