Pyrene-functionalized oligonucleotides and locked nucleic acids (LNAs): tools for fundamental research, diagnostics, and nanotechnology von Østergaard, Michael E, Hrdlicka, Patrick J

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Towards next generation antisense oligonucleotides: mesylphosphoramidate modification improves therapeutic index and duration of effect of gapmer antisense oligonucleotides von Anderson, Brooke A, Freestone, Graeme C, Low, Audrey, De-Hoyos, Cheryl L, III, William J Drury, Østergaard, Michael E, Migawa, Michael T, Fazio, Michael, Wan, W Brad, Berdeja, Andres, Scandalis, Eli, Burel, Sebastien A, Vickers, Timothy A, Crooke, Stanley T, Swayze, Eric E, Liang, Xuehai, Seth, Punit P

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Disorders caused by deficiency of succinate-CoA ligase von Ostergaard, E.

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In Vivo Evaluation of Candidate Allele-specific Mutant Huntingtin Gene Silencing Antisense Oligonucleotides von Southwell, Amber L, Skotte, Niels H, Kordasiewicz, Holly B, Østergaard, Michael E, Watt, Andrew T, Carroll, Jeffrey B, Doty, Crystal N, Villanueva, Erika B, Petoukhov, Eugenia, Vaid, Kuljeet, Xie, Yuanyun, Freier, Susan M, Swayze, Eric E, Seth, Punit P, Bennett, Clarence Frank, Hayden, Michael R

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Fatty acid conjugation enhances potency of antisense oligonucleotides in muscle von Prakash, Thazha P, Mullick, Adam E, Lee, Richard G, Yu, Jinghua, Yeh, Steve T, Low, Audrey, Chappell, Alfred E, Østergaard, Michael E, Murray, Sue, Gaus, Hans J, Swayze, Eric E, Seth, Punit P

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Simplifying the clinical classification of polymerase gamma (POLG) disease based on age of onset; studies using a cohort of 155 cases von Hikmat, Omar, Naess, Karin, Engvall, Martin, Klingenberg, Claus, Rasmussen, Magnhild, Tallaksen, Chantal ME, Brodtkorb, Eylert, Ostergaard, Elsebet, Coo, I. F. M, Pias‐Peleteiro, Leticia, Isohanni, Pirjo, Uusimaa, Johanna, Darin, Niklas, Rahman, Shamima, Bindoff, Laurence A.

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Glucagon Like Peptide 1 Receptor Agonists for Targeted Delivery of Antisense Oligonucleotides to Pancreatic Beta Cell von Knerr, Laurent, Prakash, Thazha P, Lee, Richard, Drury III, William J, Nikan, Mehran, Fu, Wuxia, Pirie, Elaine, Maria, Leonardo De, Valeur, Eric, Hayen, Ahlke, Ölwegård-Halvarsson, Maria, Broddefalk, Johan, Ämmälä, Carina, Østergaard, Michael E, Meuller, Johan, Sundström, Linda, Andersson, Patrik, Janzén, David, Jansson-Löfmark, Rasmus, Seth, Punit P, Andersson, Shalini

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Comprehensive Structure–Activity Relationship of Triantennary N‑Acetylgalactosamine Conjugated Antisense Oligonucleotides for Targeted Delivery to Hepatocytes von Prakash, Thazha P, Yu, Jinghua, Migawa, Michael T, Kinberger, Garth A, Wan, W. Brad, Østergaard, Michael E, Carty, Recaldo L, Vasquez, Guillermo, Low, Audrey, Chappell, Alfred, Schmidt, Karsten, Aghajan, Mariam, Crosby, Jeff, Murray, Heather M, Booten, Sheri L, Hsiao, Jill, Soriano, Armand, Machemer, Todd, Cauntay, Patrick, Burel, Sebastien A, Murray, Susan F, Gaus, Hans, Graham, Mark J, Swayze, Eric E, Seth, Punit P

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Mutations in PCDH21 cause autosomal recessive cone-rod dystrophy von Ostergaard, E, Batbayli, M, Duno, M, Vilhelmsen, K, Rosenberg, T

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Allele-specific suppression of mutant huntingtin using antisense oligonucleotides: providing a therapeutic option for all Huntington disease patients von Skotte, Niels H, Southwell, Amber L, Østergaard, Michael E, Carroll, Jeffrey B, Warby, Simon C, Doty, Crystal N, Petoukhov, Eugenia, Vaid, Kuljeet, Kordasiewicz, Holly, Watt, Andrew T, Freier, Susan M, Hung, Gene, Seth, Punit P, Bennett, C Frank, Swayze, Eric E, Hayden, Michael R

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Tensile and fatigue crack growth behavior of commercially pure titanium produced by laser powder bed fusion additive manufacturing von Hasib, M. Tarik, Ostergaard, Halsey E., Liu, Qian, Li, Xiaopeng, Kruzic, Jamie J.

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Synthesis and Duplex-Stabilizing Properties of Fluorinated N-Methanocarbathymidine Analogues Locked in the C3′-endo Conformation von Jung, Michael E., Dwight, Timothy A., Vigant, Frederic, Østergaard, Michael E., Swayze, Eric E., Seth, Punit P.

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Natural disease course and genotype-phenotype correlations in Complex I deficiency caused by nuclear gene defects: what we learned from 130 cases von Koene, S., Rodenburg, R. J., van der Knaap, M. S., Willemsen, M. A. A. P., Sperl, W., Laugel, V., Ostergaard, E., Tarnopolsky, M., Martin, M. A., Nesbitt, V., Fletcher, J., Edvardson, S., Procaccio, V., Slama, A., van den Heuvel, L. P. W. J., Smeitink, J. A. M.

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Nanoindentation based properties of Inconel 718 at elevated temperatures: A comparison of conventional versus additively manufactured samples von Wang, Hao, Dhiman, Abhijeet, Ostergaard, Halsey E., Zhang, Yang, Siegmund, Thomas, Kruzic, Jamie J., Tomar, Vikas

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A healthy individual with a homozygous PTCH2 frameshift variant: Are variants of PTCH2 associated with nevoid basal cell carcinoma syndrome? von Altaraihi, M., Wadt, K., Ek, J., Gerdes, A. M., Ostergaard, E.

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A Constrained Tricyclic Nucleic Acid Analogue of α‑l‑LNA: Investigating the Effects of Dual Conformational Restriction on Duplex Thermal Stability von Hanessian, Stephen, Wagger, Jernej, Merner, Bradley L, Giacometti, Robert D, Østergaard, Michael E, Swayze, Eric E, Seth, Punit P

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Characterization of the interactions of chemically-modified therapeutic nucleic acids with plasma proteins using a fluorescence polarization assay von Gaus, Hans J, Gupta, Ruchi, Chappell, Alfred E, Østergaard, Michael E, Swayze, Eric E, Seth, Punit P

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The impact of gender, puberty, and pregnancy in patients with POLG disease von Hikmat, Omar, Naess, Karin, Engvall, Martin, Klingenberg, Claus, Rasmussen, Magnhild, Tallaksen, Chantal M. E., Samsonsen, Christian, Brodtkorb, Eylert, Ostergaard, Elsebet, de Coo, Rene, Pias‐Peleteiro, Leticia, Isohanni, Pirjo, Uusimaa, Johanna, Darin, Niklas, Rahman, Shamima, Bindoff, Laurence A.

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Transient creep‐fatigue crack growth in creep‐brittle materials: Application to Alloy 718 von Pribe, Joshua D., Ostergaard, Halsey E., Siegmund, Thomas, Kruzic, Jamie J.

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Stabilin-1 and Stabilin-2 are specific receptors for the cellular internalization of phosphorothioate-modified antisense oligonucleotides (ASOs) in the liver von Miller, Colton M, Donner, Aaron J, Blank, Emma E, Egger, Andrew W, Kellar, Brianna M, Østergaard, Michael E, Seth, Punit P, Harris, Edward N

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