A Phase Ib Study of Alpelisib (BYL719), a PI3Kα-Specific Inhibitor, with Letrozole in ER+/HER2- Metastatic Breast Cancer von Mayer, Ingrid A, Abramson, Vandana G, Formisano, Luigi, Balko, Justin M, Estrada, Mónica V, Sanders, Melinda E, Juric, Dejan, Solit, David, Berger, Michael F, Won, Helen H, Li, Yisheng, Cantley, Lewis C, Winer, Eric, Arteaga, Carlos L

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Association of FGFR1 with ERα Maintains Ligand-Independent ER Transcription and Mediates Resistance to Estrogen Deprivation in ER + Breast Cancer von Formisano, Luigi, Stauffer, Kimberly M, Young, Christian D, Bhola, Neil E, Guerrero-Zotano, Angel L, Jansen, Valerie M, Estrada, Mónica M, Hutchinson, Katherine E, Giltnane, Jennifer M, Schwarz, Luis J, Lu, Yao, Balko, Justin M, Deas, Olivier, Cairo, Stefano, Judde, Jean-Gabriel, Mayer, Ingrid A, Sanders, Melinda, Dugger, Teresa C, Bianco, Roberto, Stricker, Thomas, Arteaga, Carlos L

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Proline rich 11 (PRR11) overexpression amplifies PI3K signaling and promotes antiestrogen resistance in breast cancer von Lee, Kyung-min, Guerrero-Zotano, Angel L., Servetto, Alberto, Sudhan, Dhivya R., Lin, Chang-Ching, Formisano, Luigi, Jansen, Valerie M., González-Ericsson, Paula, Sanders, Melinda E., Stricker, Thomas P., Raj, Ganesh, Dean, Kevin M., Fiolka, Reto, Cantley, Lewis C., Hanker, Ariella B., Arteaga, Carlos L.

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ER + Breast Cancers Resistant to Prolonged Neoadjuvant Letrozole Exhibit an E2F4 Transcriptional Program Sensitive to CDK4/6 Inhibitors von Guerrero-Zotano, Angel L, Stricker, Thomas P, Formisano, Luigi, Hutchinson, Katherine E, Stover, Daniel G, Lee, Kyung-Min, Schwarz, Luis J, Giltnane, Jennifer M, Estrada, Monica V, Jansen, Valerie M, Servetto, Alberto, Gavilá, Joaquín, Perez-Fidalgo, J Alejandro, Lluch, Ana, Llombart-Cussac, Antonio, Bayar, Mohamed Amine, Michiels, Stefan, André, Fabrice, Arnedos, Mónica, Guillem, Vicente, Ruiz-Simon, Amparo, Arteaga, Carlos L

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FOLFIRINOX after first-line gemcitabine-based chemotherapy in advanced pancreatic cancer: a retrospective comparison with FOLFOX and FOLFIRI schedules von Foschini, Francesca, Napolitano, Fabiana, Servetto, Alberto, Marciano, Roberta, Mozzillo, Eleonora, Carratù, Anna Chiara, Santaniello, Antonio, De Placido, Pietro, Cascetta, Priscilla, Butturini, Giovanni, Frigerio, Isabella, Regi, Paolo, Silvestris, Nicola, Delcuratolo, Sabina, Vasile, Enrico, Vivaldi, Caterina, Bianco, Cataldo, De Placido, Sabino, Formisano, Luigi, Bianco, Roberto

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Animal models of Multiple Sclerosis von Procaccini, Claudio, De Rosa, Veronica, Pucino, Valentina, Formisano, Luigi, Matarese, Giuseppe

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Role of FGFR3 in bladder cancer: Treatment landscape and future challenges von Ascione, Claudia Maria, Napolitano, Fabiana, Esposito, Daniela, Servetto, Alberto, Belli, Stefania, Santaniello, Antonio, Scagliarini, Sarah, Crocetto, Felice, Bianco, Roberto, Formisano, Luigi

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FGFR signaling and endocrine resistance in breast cancer: Challenges for the clinical development of FGFR inhibitors von Servetto, Alberto, Formisano, Luigi, Arteaga, Carlos L.

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Role of metabolism in neurodegenerative disorders von Procaccini, Claudio, Santopaolo, Marianna, Faicchia, Deriggio, Colamatteo, Alessandra, Formisano, Luigi, de Candia, Paola, Galgani, Mario, De Rosa, Veronica, Matarese, Giuseppe

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KRAS mutations in advanced non-small cell lung cancer: From biology to novel therapeutic strategies von Liguori, Luigi, Salomone, Fabio, Viggiano, Angela, Sabbatino, Francesco, Pepe, Stefano, Formisano, Luigi, Bianco, Roberto, Servetto, Alberto

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Transcriptional and epigenetic regulation of ncx1 and ncx3 in the brain von Formisano, Luigi, Guida, Natascia, Mascolo, Luigi, Serani, Angelo, Laudati, Giusy, Pizzorusso, Vincenzo, Annunziato, Lucio

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Combining Immune Checkpoint Inhibitors with Anti-Angiogenic Agents von Ciciola, Paola, Cascetta, Priscilla, Bianco, Cataldo, Formisano, Luigi, Bianco, Roberto

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Aberrant FGFR signaling mediates resistance to CDK4/6 inhibitors in ER+ breast cancer von Formisano, Luigi, Lu, Yao, Servetto, Alberto, Hanker, Ariella B., Jansen, Valerie M., Bauer, Joshua A., Sudhan, Dhivya R., Guerrero-Zotano, Angel L., Croessmann, Sarah, Guo, Yan, Ericsson, Paula Gonzalez, Lee, Kyung-min, Nixon, Mellissa J., Schwarz, Luis J., Sanders, Melinda E., Dugger, Teresa C., Cruz, Marcelo Rocha, Behdad, Amir, Cristofanilli, Massimo, Bardia, Aditya, O’Shaughnessy, Joyce, Nagy, Rebecca J., Lanman, Richard B., Solovieff, Nadia, He, Wei, Miller, Michelle, Su, Fei, Shyr, Yu, Mayer, Ingrid A., Balko, Justin M., Arteaga, Carlos L.

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CDK 4/6 Inhibitors as Single Agent in Advanced Solid Tumors von Schettini, Francesco, De Santo, Irene, Rea, Carmen G, De Placido, Pietro, Formisano, Luigi, Giuliano, Mario, Arpino, Grazia, De Laurentiis, Michelino, Puglisi, Fabio, De Placido, Sabino, Del Mastro, Lucia

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Mechanisms of lapatinib resistance in HER2-driven breast cancer von D’Amato, Valentina, Raimondo, Lucia, Formisano, Luigi, Giuliano, Mario, De Placido, Sabino, Rosa, Roberta, Bianco, Roberto

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Tumour Microenvironment and Immune Evasion in EGFR Addicted NSCLC: Hurdles and Possibilities von Santaniello, Antonio, Napolitano, Fabiana, Servetto, Alberto, De Placido, Pietro, Silvestris, Nicola, Bianco, Cataldo, Formisano, Luigi, Bianco, Roberto

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Sp3/REST/HDAC1/HDAC2 Complex Represses and Sp1/HIF-1/p300 Complex Activates ncx1 Gene Transcription, in Brain Ischemia and in Ischemic Brain Preconditioning, by Epigenetic Mechanis... von Formisano, Luigi, Guida, Natascia, Valsecchi, Valeria, Cantile, Maria, Cuomo, Ornella, Vinciguerra, Antonio, Laudati, Giusy, Pignataro, Giuseppe, Sirabella, Rossana, Di Renzo, Gianfranco, Annunziato, Lucio

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Mechanisms of resistance to mTOR inhibitors von Formisano, Luigi, Napolitano, Fabiana, Rosa, Roberta, D’Amato, Valentina, Servetto, Alberto, Marciano, Roberta, De Placido, Pietro, Bianco, Cataldo, Bianco, Roberto

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EGFR and HER2 hyper-activation mediates resistance to endocrine therapy and CDK4/6 inhibitors in ER+ breast cancer von Belli, Stefania, Esposito, Daniela, Ascione, Claudia M., Messina, Francesca, Napolitano, Fabiana, Servetto, Alberto, De Angelis, Carmine, Bianco, Roberto, Formisano, Luigi

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Stroke by inducing HDAC9-dependent deacetylation of HIF-1 and Sp1, promotes TfR1 transcription and GPX4 reduction, thus determining ferroptotic neuronal death von Sanguigno, Luca, Guida, Natascia, Anzilotti, Serenella, Cuomo, Ornella, Mascolo, Luigi, Serani, Angelo, Brancaccio, Paola, Pennacchio, Giuseppina, Licastro, Ester, Pignataro, Giuseppe, Molinaro, Pasquale, Annunziato, Lucio, Formisano, Luigi

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