A Phase Ib Study of Alpelisib (BYL719), a PI3Kα-Specific Inhibitor, with Letrozole in ER+/HER2- Metastatic Breast Cancer von Mayer, Ingrid A, Abramson, Vandana G, Formisano, Luigi, Balko, Justin M, Estrada, Mónica V, Sanders, Melinda E, Juric, Dejan, Solit, David, Berger, Michael F, Won, Helen H, Li, Yisheng, Cantley, Lewis C, Winer, Eric, Arteaga, Carlos L

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Association of FGFR1 with ERα Maintains Ligand-Independent ER Transcription and Mediates Resistance to Estrogen Deprivation in ER + Breast Cancer von Formisano, Luigi, Stauffer, Kimberly M, Young, Christian D, Bhola, Neil E, Guerrero-Zotano, Angel L, Jansen, Valerie M, Estrada, Mónica M, Hutchinson, Katherine E, Giltnane, Jennifer M, Schwarz, Luis J, Lu, Yao, Balko, Justin M, Deas, Olivier, Cairo, Stefano, Judde, Jean-Gabriel, Mayer, Ingrid A, Sanders, Melinda, Dugger, Teresa C, Bianco, Roberto, Stricker, Thomas, Arteaga, Carlos L

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Proline rich 11 (PRR11) overexpression amplifies PI3K signaling and promotes antiestrogen resistance in breast cancer von Lee, Kyung-min, Guerrero-Zotano, Angel L., Servetto, Alberto, Sudhan, Dhivya R., Lin, Chang-Ching, Formisano, Luigi, Jansen, Valerie M., González-Ericsson, Paula, Sanders, Melinda E., Stricker, Thomas P., Raj, Ganesh, Dean, Kevin M., Fiolka, Reto, Cantley, Lewis C., Hanker, Ariella B., Arteaga, Carlos L.

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Animal models of Multiple Sclerosis von Procaccini, Claudio, De Rosa, Veronica, Pucino, Valentina, Formisano, Luigi, Matarese, Giuseppe

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Role of FGFR3 in bladder cancer: Treatment landscape and future challenges von Ascione, Claudia Maria, Napolitano, Fabiana, Esposito, Daniela, Servetto, Alberto, Belli, Stefania, Santaniello, Antonio, Scagliarini, Sarah, Crocetto, Felice, Bianco, Roberto, Formisano, Luigi

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ER + Breast Cancers Resistant to Prolonged Neoadjuvant Letrozole Exhibit an E2F4 Transcriptional Program Sensitive to CDK4/6 Inhibitors von Guerrero-Zotano, Angel L, Stricker, Thomas P, Formisano, Luigi, Hutchinson, Katherine E, Stover, Daniel G, Lee, Kyung-Min, Schwarz, Luis J, Giltnane, Jennifer M, Estrada, Monica V, Jansen, Valerie M, Servetto, Alberto, Gavilá, Joaquín, Perez-Fidalgo, J Alejandro, Lluch, Ana, Llombart-Cussac, Antonio, Bayar, Mohamed Amine, Michiels, Stefan, André, Fabrice, Arnedos, Mónica, Guillem, Vicente, Ruiz-Simon, Amparo, Arteaga, Carlos L

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Role of metabolism in neurodegenerative disorders von Procaccini, Claudio, Santopaolo, Marianna, Faicchia, Deriggio, Colamatteo, Alessandra, Formisano, Luigi, de Candia, Paola, Galgani, Mario, De Rosa, Veronica, Matarese, Giuseppe

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CDK 4/6 Inhibitors as Single Agent in Advanced Solid Tumors von Schettini, Francesco, De Santo, Irene, Rea, Carmen G, De Placido, Pietro, Formisano, Luigi, Giuliano, Mario, Arpino, Grazia, De Laurentiis, Michelino, Puglisi, Fabio, De Placido, Sabino, Del Mastro, Lucia

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Mechanisms of resistance to mTOR inhibitors von Formisano, Luigi, Napolitano, Fabiana, Rosa, Roberta, D’Amato, Valentina, Servetto, Alberto, Marciano, Roberta, De Placido, Pietro, Bianco, Cataldo, Bianco, Roberto

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FGFR signaling and endocrine resistance in breast cancer: Challenges for the clinical development of FGFR inhibitors von Servetto, Alberto, Formisano, Luigi, Arteaga, Carlos L.

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Regulation of autophagosome biogenesis by OFD1‐mediated selective autophagy von Morleo, Manuela, Brillante, Simona, Formisano, Umberto, Ferrante, Luigi, Carbone, Fabrizia, Iaconis, Daniela, Palma, Alessandro, Buonomo, Viviana, Maione, Angela Serena, Grumati, Paolo, Settembre, Carmine, Franco, Brunella

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KRAS mutations in advanced non-small cell lung cancer: From biology to novel therapeutic strategies von Liguori, Luigi, Salomone, Fabio, Viggiano, Angela, Sabbatino, Francesco, Pepe, Stefano, Formisano, Luigi, Bianco, Roberto, Servetto, Alberto

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Combining Immune Checkpoint Inhibitors with Anti-Angiogenic Agents von Ciciola, Paola, Cascetta, Priscilla, Bianco, Cataldo, Formisano, Luigi, Bianco, Roberto

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Tumour Microenvironment and Immune Evasion in EGFR Addicted NSCLC: Hurdles and Possibilities von Santaniello, Antonio, Napolitano, Fabiana, Servetto, Alberto, De Placido, Pietro, Silvestris, Nicola, Bianco, Cataldo, Formisano, Luigi, Bianco, Roberto

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Sp3/REST/HDAC1/HDAC2 Complex Represses and Sp1/HIF-1/p300 Complex Activates ncx1 Gene Transcription, in Brain Ischemia and in Ischemic Brain Preconditioning, by Epigenetic Mechanis... von Formisano, Luigi, Guida, Natascia, Valsecchi, Valeria, Cantile, Maria, Cuomo, Ornella, Vinciguerra, Antonio, Laudati, Giusy, Pignataro, Giuseppe, Sirabella, Rossana, Di Renzo, Gianfranco, Annunziato, Lucio

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EGFR and HER2 hyper-activation mediates resistance to endocrine therapy and CDK4/6 inhibitors in ER+ breast cancer von Belli, Stefania, Esposito, Daniela, Ascione, Claudia M., Messina, Francesca, Napolitano, Fabiana, Servetto, Alberto, De Angelis, Carmine, Bianco, Roberto, Formisano, Luigi

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RET rearrangements in non-small cell lung cancer: Evolving treatment landscape and future challenges von Servetto, Alberto, Esposito, Daniela, Ferrara, Roberto, Signorelli, Diego, Belli, Stefania, Napolitano, Fabiana, Santaniello, Antonio, Ciciola, Paola, Formisano, Luigi, Bianco, Roberto

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Transcriptional and epigenetic regulation of ncx1 and ncx3 in the brain von Formisano, Luigi, Guida, Natascia, Mascolo, Luigi, Serani, Angelo, Laudati, Giusy, Pizzorusso, Vincenzo, Annunziato, Lucio

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Emerging Role of DREAM in Healthy Brain and Neurological Diseases von Molinaro, Pasquale, Sanguigno, Luca, Casamassa, Antonella, Valsecchi, Valeria, Sirabella, Rossana, Pignataro, Giuseppe, Annunziato, Lucio, Formisano, Luigi

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GATA3 (GATA-Binding Protein 3)/KMT2A (Lysine-Methyltransferase-2A) Complex by Increasing H3K4-3me (Trimethylated Lysine-4 of Histone-3) Upregulates NCX3 (Na + -Ca 2+ Exchanger 3) T... von Guida, Natascia, Mascolo, Luigi, Serani, Angelo, Cuomo, Ornella, Anzilotti, Serenella, Brancaccio, Paola, Pignataro, Giuseppe, Molinaro, Pasquale, Annunziato, Lucio, Formisano, Luigi

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