Multiple roles of caspase‐8 in cell death, inflammation, and innate immunity von Orning, Pontus, Lien, Egil

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Pathogen blockade of TAK1 triggers caspase-8-dependent cleavage of gasdermin D and cell death von Orning, Pontus, Weng, Dan, Starheim, Kristian, Ratner, Dmitry, Best, Zachary, Lee, Bettina, Brooks, Alexandria, Xia, Shiyu, Wu, Hao, Kelliher, Michelle A, Berger, Scott B, Gough, Peter J, Bertin, John, Proulx, Megan M, Goguen, Jon D, Kayagaki, Nobuhiko, Fitzgerald, Katherine A, Lien, Egil

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RIP1 kinase activity promotes steatohepatitis through mediating cell death and inflammation in macrophages von Tao, Liang, Yi, Yuguo, Chen, Yuxin, Zhang, Haibing, Orning, Pontus, Lien, Egil, Jie, Jiapeng, Zhang, Weigao, Xu, Qian, Li, Yang, Ding, Zhao, Wu, Chao, Ding, Qiurong, Wang, Junsong, Zhang, Jianfa, Weng, Dan

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Identification of QS-21 as an Inflammasome-activating Molecular Component of Saponin Adjuvants von Marty-Roix, Robyn, Vladimer, Gregory I., Pouliot, Kimberly, Weng, Dan, Buglione-Corbett, Rachel, West, Kim, MacMicking, John D., Chee, Jonathan D., Wang, Shixia, Lu, Shan, Lien, Egil

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Inhibition of HSP90 and Activation of HSF1 Diminish Macrophage NLRP3 Inflammasome Activity in Alcohol‐Associated Liver Injury von Choudhury, Asmita, Bullock, Daniel, Lim, Arlene, Argemi, Josepmaria, Orning, Pontus, Lien, Egil, Bataller, Ramon, Mandrekar, Pranoti

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MLKL-Driven Inflammasome Activation and Caspase-8 Mediate Inflammatory Cell Death in Influenza A Virus Infection von Lei, Xuqiu, Chen, Yongzhi, Lien, Egil, Fitzgerald, Katherine A

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The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia-reperfusion injury von Sandanger, Øystein, Ranheim, Trine, Vinge, Leif Erik, Bliksøen, Marte, Alfsnes, Katrine, Finsen, Alexandra V, Dahl, Christen P, Askevold, Erik T, Florholmen, Geir, Christensen, Geir, Fitzgerald, Katherine A, Lien, Egil, Valen, Guro, Espevik, Terje, Aukrust, Pål, Yndestad, Arne

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Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death von Weng, Dan, Marty-Roix, Robyn, Ganesan, Sandhya, Proulx, Megan K., Vladimer, Gregory I., Kaiser, William J., Mocarski, Edward S., Pouliot, Kimberly, Chan, Francis Ka-Ming, Kelliher, Michelle A., Harris, Phillip A., Bertin, John, Gough, Peter J., Shayakhmetov, Dmitry M., Goguen, Jon D., Fitzgerald, Katherine A., Silverman, Neal, Lien, Egil

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NLRP3 inflammasome mediates oxidative stress-induced pancreatic islet dysfunction von Sokolova, Marina, Sahraoui, Afaf, Høyem, Merete, Øgaard, Jonas, Lien, Egil, Aukrust, Pål, Yndestad, Arne, Ranheim, Trine, Scholz, Hanne

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The Yersinia pestis Effector YopM Inhibits Pyrin Inflammasome Activation von Ratner, Dmitry, Orning, M Pontus A, Proulx, Megan K, Wang, Donghai, Gavrilin, Mikhail A, Wewers, Mark D, Alnemri, Emad S, Johnson, Peter F, Lee, Bettina, Mecsas, Joan, Kayagaki, Nobuhiko, Goguen, Jon D, Lien, Egil

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Caspase-8 mediates inflammation and disease in rodent malaria von Pereira, Larissa M. N., Assis, Patrícia A., de Araújo, Natalia M., Durso, Danielle F., Junqueira, Caroline, Ataíde, Marco Antônio, Pereira, Dhelio B., Lien, Egil, Fitzgerald, Katherine A., Zamboni, Dario S., Golenbock, Douglas T., Gazzinelli, Ricardo T.

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MD-2-mediated Ionic Interactions between Lipid A and TLR4 Are Essential for Receptor Activation von Meng, Jianmin, Lien, Egil, Golenbock, Douglas T.

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The NLRP12 Inflammasome Recognizes Yersinia pestis von Vladimer, Gregory I., Weng, Dan, Paquette, Sara W. Montminy, Vanaja, Sivapriya Kailasan, Rathinam, Vijay A.K., Aune, Marie Hjelmseth, Conlon, Joseph E., Burbage, Joseph J., Proulx, Megan K., Liu, Qin, Reed, George, Mecsas, Joan C., Iwakura, Yoichiro, Bertin, John, Goguen, Jon D., Fitzgerald, Katherine A., Lien, Egil

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Bacterial secretion systems and regulation of inflammasome activation von Ratner, Dmitry, Orning, M. Pontus A., Lien, Egil

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Author Correction: Caspase-8 mediates inflammation and disease in rodent malaria von Pereira, Larissa M. N., Assis, Patrícia A., de Araújo, Natalia M., Durso, Danielle F., Junqueira, Caroline, Ataíde, Marco Antônio, Pereira, Dhelio B., Lien, Egil, Fitzgerald, Katherine A., Zamboni, Dario S., Golenbock, Douglas T., Gazzinelli, Ricardo T.

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The Rab11a GTPase Controls Toll-like Receptor 4-Induced Activation of Interferon Regulatory Factor-3 on Phagosomes von Husebye, Harald, Aune, Marie Hjelmseth, Stenvik, Jørgen, Samstad, Eivind, Skjeldal, Frode, Halaas, Øyvind, Nilsen, Nadra J., Stenmark, Harald, Latz, Eicke, Lien, Egil, Mollnes, Tom Eirik, Bakke, Oddmund, Espevik, Terje

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A Role for the Adaptor Proteins TRAM and TRIF in Toll-like Receptor 2 Signaling von Nilsen, Nadra J., Vladimer, Gregory I., Stenvik, Jørgen, Orning, M. Pontus A., Zeid-Kilani, Maria V., Bugge, Marit, Bergstroem, Bjarte, Conlon, Joseph, Husebye, Harald, Hise, Amy G., Fitzgerald, Katherine A., Espevik, Terje, Lien, Egil

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Absence of the inflammasome adaptor ASC reduces hypoxia-induced pulmonary hypertension in mice von Cero, Fadila Telarevic, Hillestad, Vigdis, Sjaastad, Ivar, Yndestad, Arne, Aukrust, Pål, Ranheim, Trine, Lunde, Ida Gjervold, Olsen, Maria Belland, Lien, Egil, Zhang, Lili, Haugstad, Solveig Bjærum, Løberg, Else Marit, Christensen, Geir, Larsen, Karl-Otto, Skjønsberg, Ole Henning

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TLR9 signals after translocating from the ER to CpG DNA in the lysosome von Espevik, Terje, Monks, Brian G, Golenbock, Douglas T, Latz, Eicke, Knetter, Cathrine F, Nilsen, Nadra J, Lien, Egil, Visintin, Alberto, Fitzgerald, Katherine A, Schoenemeyer, Annett

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Virulence factors of Yersinia pestis are overcome by a strong lipopolysaccharide response von Lien, Egil, Montminy, Sara W, Khan, Naseema, McGrath, Sara, Walkowicz, Mitchell J, Sharp, Fiona, Conlon, Joseph E, Fukase, Koichi, Kusumoto, Shoichi, Sweet, Charles, Miyake, Kensuke, Akira, Shizuo, Cotter, Robert J, Goguen, Jon D

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