Opioid analgesia for acute low back pain and neck pain (the OPAL trial): a randomised placebo-controlled trial von Jones, Caitlin M P, Day, Richard O, Koes, Bart W, Latimer, Jane, Maher, Chris G, McLachlan, Andrew J, Billot, Laurent, Shan, Sana, Lin, Chung-Wei Christine, McLachlan, Hanan, Webb, Melissa, Hamilton, Melanie, Ahedi, Harbeer, Barber, Angie, Mak, Wendy, Mathieson, Stephanie, Petrova, Veronika, Bompoint, Severine, Shan, Sana, Murnion, Bridin, Buckley, Nicholas, Demirkol, Apo, Wrigley, Paul, Needs, Christopher, Brooks, Louise, Cantori, Samuel, Preisz, Paul, Aitken, James, Allan, Sujata, Burke, Michael, Cameron, Greg, Cepeda, Francisco Javier Valencia, Davis, Christopher, Dullur, Jayasree, Emmanuel, Joseph, Errey, Catherine, Fieuw-Makaroff, Sabine, Gaudry, Adam, Genua, L, Longhurst, Ian, McCroary, Kenneth, Merhi, Diana, Nguyen, Tanya, Obayd, Zahra Rassoly, Penm, Michelle, Pobbathi, Sharan, Poh, William S, Schnitzler, Paul, Shahnaz, Sabiha, Tan, Ven, Tang, Danny, Tan, Brian, Thu, Win Kyaw, Triantopolous, Thrasivolous, Venkatesan, Ramana, Wong, Wicky Chun Fai, Yang, Shu Ching

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Effects of Tibolone and Continuous Combined Conjugated Equine Estrogen/Medroxyprogesterone Acetate on the Endometrium and Vaginal Bleeding: Results of the OPAL Study von Langer, Robert D., Landgren, Britt Marie, Rymer, Janice, Helmond, Frans A.

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Opioids for back and neck pain: the OPAL trial – Authors' reply von Jones, Caitlin M P, Day, Richard O, Koes, Bart W, Latimer, Jane, Maher, Chris G, McLachlan, Andrew J, Billot, Laurent, Shan, Sana, Lin, Chung-Wei Christine

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Patiromer in Patients with Kidney Disease and Hyperkalemia Receiving RAAS Inhibitors von Weir, Matthew R, Bakris, George L, Bushinsky, David A, Mayo, Martha R, Garza, Dahlia, Stasiv, Yuri, Wittes, Janet, Christ-Schmidt, Heidi, Berman, Lance, Pitt, Bertram

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Ultrasound protocols to measure carotid intima-media thickness: a post-hoc analysis of the OPAL study von Dogan, S., Plantinga, Y., Evans, G. W., Meijer, R., Grobbee, D. E., Bots, M. L.

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The effect of tibolone and continuous combined conjugated equine oestrogens plus medroxyprogesterone acetate on progression of carotid intima–media thickness: the Osteoporosis Prev... von Bots, Michiel L., Evans, Gregory W., Riley, Ward, McBride, Karen H., Paskett, Electra D., Helmond, Frans A., Grobbee, Diederick E.

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The effect of tibolone and continuous combined conjugated equine oestrogens plus medroxy progesterone acetate on progression of carotid intima-media thickness : the Osteoporosis pr... von CLARKSON, Thomas B, BOTS, Michiel L, EVANS, Gregory W, RILEY, Ward, MCBRIDE, Karen H, PASKETT, Electra D, HELMOND, Frans A, GROBBEE, Diederick E

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Optimizing Preventive Adjuvant Linac-Based (OPAL) Radiation: A Phase 2 Trial of Daily Partial Breast Irradiation von Reddy, Jay P., Lei, Xiudong, Bloom, Elizabeth S., Reed, Valerie K., Schlembach, Pamela J., Arzu, Isidora, Mayo, Lauren, Chun, Stephen G., Ahmad, Neelofur R., Stauder, Michael C., Gopal, Ramesh, Kaiser, Kels, Fang, Penny, Smith, Benjamin D.

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The Osteoporosis Prevention and Arterial effects of tiboLone (OPAL) study: design and baseline characteristics von Bots, Michiel L, Evans, Gregory W, Riley, Ward, Meijer, Rudy, McBride, Karen H, Paskett, Electra D, Helmond, Frans A, Grobbee, Diederick E, for the OPAL Investigators

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The OPAL study: A phase II study to evaluate the efficacy, safety, and tolerability of tosedostat (CHR-2797) in elderly subjects with treatment refractory or relapsed acute myeloid... von Cortes, J. E., Feldman, E. J., Yee, K. W., Toal, M. J., Richardson, A., Charman, A., Flores, N.

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Treatment effects of high‐dose antithrombin without concomitant heparin in patients with severe sepsis with or without disseminated intravascular coagulation von KIENAST, J., JUERS, M., WIEDERMANN, C. J., HOFFMANN, J. N., OSTERMANN, H., STRAUSS, R., KEINECKE, H‐O., WARREN, B. L., OPAL, S. M.

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Procalcitonin-Guided Use of Antibiotics for Lower Respiratory Tract Infection von Huang, David T, Yealy, Donald M, Filbin, Michael R, Brown, Aaron M, Chang, Chung-Chou H, Doi, Yohei, Donnino, Michael W, Fine, Jonathan, Fine, Michael J, Fischer, Michelle A, Holst, John M, Hou, Peter C, Kellum, John A, Khan, Feras, Kurz, Michael C, Lotfipour, Shahram, LoVecchio, Frank, Peck-Palmer, Octavia M, Pike, Francis, Prunty, Heather, Sherwin, Robert L, Southerland, Lauren, Terndrup, Thomas, Weissfeld, Lisa A, Yabes, Jonathan, Angus, Derek C

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Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer von Riggan, Marjorie J, Beesley, Jonathan, Soucy, Penny, Aalfs, Cora M, Adams, Marcia, Arnold, Norbert, Arun, Banu K, Bean, Yukie, Bermisheva, Marina, Birrer, Michael J, Blankstein, Kenneth, Bonanni, Bernardo, Bradbury, Angela R, Broberg, Per, Campbell, Ian, Cannioto, Rikki, Cescon, Terence, Chan, Salina B, Chanock, Stephen, Claes, Kathleen B M, Conner, Thomas, Dansonka-Mieszkowska, Agnieszka, Davidson, Rosemarie, Dürst, Matthias, Ellis, Steve, Fasching, Peter A, Ferguson, Sarah, Frost, Debra, Gentry-Maharaj, Aleksandra, Gore, Martin, Gronwald, Jacek, Gruber, Stephen, Håkansson, Niclas, Hauke, Jan, Hildebrandt, Michelle A T, Høgdall, Claus K, Hogervorst, Frans B L, Hulick, Peter J, Imyanitov, Evgeny N, Izatt, Louise, Izquierdo, Angel, Jensen, Allan, Karnezis, Anthony, Kupryjanczyk, Jolanta, Lambrechts, Diether, Lee, Jong Won, Lele, Shashikant B, Leroux, Dominique, Lesueur, Fabienne, Lilyquist, Jenna, Mai, Phuong L, McAlpine, Jessica N, McGuire, Valerie, Mensenkamp, Arjen R, Modugno, Francesmary, Moes-Sosnowska, Joanna, Mulligan, Anna Marie, Musinsky, Jacob, Nedergaard, Lotte, Ness, Roberta B, Nevanlinna, Heli, Niederacher, Dieter, Nussbaum, Robert L, Onland-Moret, N Charlotte, Paul, James, Pelttari, Liisa M, Pezzani, Lidia, Phillips, Kelly-Anne, Poppe, Bruce, Prieur, Fabienne, Prokofyeva, Darya, Rice, Patricia, Rodriguez, Gustavo C, Rookus, Matti A, Senter, Leigha, Shelford, Tameka, Siddiqui, Nadeem, Side, Lucy E, Stadler, Zsofia, Sutphen, Rebecca, Sutter, Christian, Szabo, Csilla I, Terry, Kathryn L, Tihomirova, Laima, Tung, Nadine, Van Heetvelde, Mattias, Varon-Mateeva, Raymonda, Walsh, Christine, Wappenschmidt, Barbara, Webb, Penelope M, Weinberg, Clarice R, Weitzel, Jeffrey N, Yang, Hannah, Goodman, Marc T, Park, Sue K, Risch, Harvey A, Offit, Kenneth, Simard, Jacques, Chenevix-Trench, Georgia, Goode, Ellen L

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Effect of Selepressin vs Placebo on Ventilator- and Vasopressor-Free Days in Patients With Septic Shock: The SEPSIS-ACT Randomized Clinical Trial von Laterre, Pierre-Francois, Berry, Scott M, Blemings, Allan, Carlsen, Jan E, François, Bruno, Graves, Todd, Jacobsen, Karsten, Lewis, Roger J, Opal, Steven M, Perner, Anders, Pickkers, Peter, Russell, James A, Windeløv, Nis A, Yealy, Donald M, Asfar, Pierre, Bestle, Morten H, Muller, Grégoire, Bruel, Cédric, Brulé, Noëlle, Decruyenaere, Johan, Dive, Alain-Michel, Dugernier, Thierry, Krell, Kenneth, Lefrant, Jean-Yves, Megarbane, Bruno, Mercier, Emmanuelle, Mira, Jean-Paul, Quenot, Jean-Pierre, Rasmussen, Bodil Steen, Thorsen-Meyer, Hans-Christian, Vander Laenen, Margot, Vang, Marianne Lauridsen, Vignon, Philippe, Vinatier, Isabelle, Wichmann, Sine, Wittebole, Xavier, Kjølbye, Anne Louise, Angus, Derek C

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High-dose antithrombin III in the treatment of severe sepsis in patients with a high risk of death: Efficacy and safety von Wiedermann, Christian J, Hoffmann, Johannes N, Juers, Mathias, Ostermann, Helmut, Kienast, Joachim, Briegel, Josef, Strauss, Richard, Keinecke, Heinz-Otto, Warren, Brian L, Opal, Steven M

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Polygenic risk modeling for prediction of epithelial ovarian cancer risk von Dareng, Eileen O, Tyrer, Jonathan P, Barnes, Daniel R, Jones, Michelle R, Yang, Xin, Aben, Katja K H, Adank, Muriel A, Agata, Simona, Andrulis, Irene L, Anton-Culver, Hoda, Antonenkova, Natalia N, Aravantinos, Gerasimos, Arun, Banu K, Augustinsson, Annelie, Balmaña, Judith, Bandera, Elisa V, Barkardottir, Rosa B, Barrowdale, Daniel, Beckmann, Matthias W, Beeghly-Fadiel, Alicia, Benitez, Javier, Bermisheva, Marina, Bernardini, Marcus Q, Bjorge, Line, Black, Amanda, Bogdanova, Natalia V, Bonanni, Bernardo, Borg, Ake, Brenton, James D, Budzilowska, Agnieszka, Butzow, Ralf, Buys, Saundra S, Cai, Hui, Caligo, Maria A, Campbell, Ian, Cannioto, Rikki, Cassingham, Hayley, Chang-Claude, Jenny, Chanock, Stephen J, Chen, Kexin, Chiew, Yoke-Eng, Chung, Wendy K, Claes, Kathleen B M, Colonna, Sarah, Cook, Linda S, Couch, Fergus J, Daly, Mary B, Dao, Fanny, Davies, Eleanor, de la Hoya, Miguel, de Putter, Robin, Dennis, Joe, DePersia, Allison, Devilee, Peter, Diez, Orland, Ding, Yuan Chun, Doherty, Jennifer A, Domchek, Susan M, Dörk, Thilo, du Bois, Andreas, Dürst, Matthias, Eccles, Diana M, Eliassen, Heather A, Engel, Christoph, Evans, Gareth D, Fasching, Peter A, Flanagan, James M, Fortner, Renée T, Machackova, Eva, Friedman, Eitan, Ganz, Patricia A, Garber, Judy, Gensini, Francesca, Giles, Graham G, Glendon, Gord, Godwin, Andrew K, Goodman, Marc T, Greene, Mark H, Gronwald, Jacek, Hahnen, Eric, Haiman, Christopher A, Håkansson, Niclas, Hamann, Ute, Hansen, Thomas V O, Harris, Holly R, Hartman, Mikael, Heitz, Florian, Hildebrandt, Michelle A T, Høgdall, Estrid, Høgdall, Claus K, Hopper, John L, Huang, Ruea-Yea, Huff, Chad, Hulick, Peter J, Huntsman, David G, Imyanitov, Evgeny N, Isaacs, Claudine, Jakubowska, Anna, James, Paul A, Janavicius, Ramunas

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Benefit/risk profile of high-dose antithrombin in patients with severe sepsis treated with and without concomitant heparin von Hoffmann, Johannes N., Wiedermann, Christian J., Juers, Mathias, Ostermann, Helmut, Kienast, Joachim, Briegel, Josef, Strauss, Richard, Warren, Brian L., Opal, Steven M.

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Polygenic risk modeling for prediction of epithelial ovarian cancer risk (vol 30, pg 349, 2021) von Dareng, EO, Tyrer, JP, Barnes, DR, Jones, MR, Yang, X, Aben, KKH, Adank, MA, Agata, S, Andrulis, IL, Anton-Culver, H

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Correction: Polygenic risk modeling for prediction of epithelial ovarian cancer risk von Dareng, Eileen O, Tyrer, Jonathan P, Barnes, Daniel R, Jones, Michelle R, Yang, Xin, Aben, Katja K H, Adank, Muriel A, Agata, Simona, Andrulis, Irene L, Anton-Culver, Hoda, Antonenkova, Natalia N, Aravantinos, Gerasimos, Arun, Banu K, Augustinsson, Annelie, Balmaña, Judith, Bandera, Elisa V, Barkardottir, Rosa B, Barrowdale, Daniel, Beckmann, Matthias W, Beeghly-Fadiel, Alicia, Benitez, Javier, Bermisheva, Marina, Bernardini, Marcus Q, Bjorge, Line, Black, Amanda, Bogdanova, Natalia V, Bonanni, Bernardo, Borg, Ake, Brenton, James D, Budzilowska, Agnieszka, Butzow, Ralf, Buys, Saundra S, Cai, Hui, Caligo, Maria A, Campbell, Ian, Cannioto, Rikki, Cassingham, Hayley, Chang-Claude, Jenny, Chanock, Stephen J, Chen, Kexin, Chiew, Yoke-Eng, Chung, Wendy K, Claes, Kathleen B M, Colonna, Sarah, Cook, Linda S, Couch, Fergus J, Daly, Mary B, Dao, Fanny, Davies, Eleanor, de la Hoya, Miguel, de Putter, Robin, Dennis, Joe, DePersia, Allison, Devilee, Peter, Diez, Orland, Ding, Yuan Chun, Doherty, Jennifer A, Domchek, Susan M, Dörk, Thilo, du Bois, Andreas, Dürst, Matthias, Eccles, Diana M, Eliassen, Heather A, Engel, Christoph, Evans, Gareth D, Fasching, Peter A, Flanagan, James M, Fortner, Renée T, Machackova, Eva, Friedman, Eitan, Ganz, Patricia A, Garber, Judy, Gensini, Francesca, Giles, Graham G, Glendon, Gord, Godwin, Andrew K, Goodman, Marc T, Greene, Mark H, Gronwald, Jacek, Hahnen, Eric, Haiman, Christopher A, Håkansson, Niclas, Hamann, Ute, Hansen, Thomas V O, Harris, Holly R, Hartman, Mikael, Heitz, Florian, Hildebrandt, Michelle A T, Høgdall, Estrid, Høgdall, Claus K, Hopper, John L, Huang, Ruea-Yea, Huff, Chad, Hulick, Peter J, Huntsman, David G, Imyanitov, Evgeny N, Isaacs, Claudine, Jakubowska, Anna, James, Paul A, Janavicius, Ramunas

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Efficacy and safety of a phospholipid emulsion (GR270773) in Gram-negative severe sepsis: Results of a phase II multicenter, randomized, placebo-controlled, dose-finding clinical t... von Phillip Dellinger, R, Tomayko, John F, Angus, Derek C, Opal, Steven, Cupo, Michael A, McDermott, Sharon, Ducher, Annie, Calandra, Thierry, Cohen, Jonathan

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