Distinct Regulatory Mechanisms and Functions for p53-Activated and p53-Repressed DNA Damage Response Genes in Embryonic Stem Cells von Li, Mangmang, He, Yunlong, Dubois, Wendy, Wu, Xiaolin, Shi, Jianxin, Huang, Jing

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An Apela RNA-Containing Negative Feedback Loop Regulates p53-Mediated Apoptosis in Embryonic Stem Cells von Li, Mangmang, Gou, Hongfeng, Tripathi, Brajendra K., Huang, Jing, Jiang, Shunlin, Dubois, Wendy, Waybright, Tim, Lei, Ming, Shi, Jianxin, Zhou, Ming, Huang, Jing

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Regulation of MicroRNA Expression and Abundance during Lymphopoiesis von Kuchen, Stefan, Resch, Wolfgang, Yamane, Arito, Kuo, Nan, Li, Zhiyu, Chakraborty, Tirtha, Wei, Lai, Laurence, Arian, Yasuda, Tomoharu, Peng, Siying, Hu-Li, Jane, Lu, Kristina, Dubois, Wendy, Kitamura, Yoshiaki, Charles, Nicolas, Sun, Hong-wei, Muljo, Stefan, Schwartzberg, Pamela L., Paul, William E., O'Shea, John, Rajewsky, Klaus, Casellas, Rafael

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Increased Mammalian Lifespan and a Segmental and Tissue-Specific Slowing of Aging after Genetic Reduction of mTOR Expression von Wu, J. Julie, Liu, Jie, Chen, Edmund B., Wang, Jennifer J., Cao, Liu, Narayan, Nisha, Fergusson, Marie M., Rovira, Ilsa I., Allen, Michele, Springer, Danielle A., Lago, Cory U., Zhang, Shuling, DuBois, Wendy, Ward, Theresa, deCabo, Rafael, Gavrilova, Oksana, Mock, Beverly, Finkel, Toren

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CBFB cooperates with p53 to maintain TAp73 expression and suppress breast cancer von Malik, Navdeep, Yan, Hualong, Yang, Howard H., Ayaz, Gamze, DuBois, Wendy, Tseng, Yu-Chou, Kim, Young-Im, Jiang, Shunlin, Liu, Chengyu, Lee, Maxwell, Huang, Jing

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mTOR intersects antibody-inducing signals from TACI in marginal zone B cells von Sintes, Jordi, Gentile, Maurizio, Zhang, Shuling, Garcia-Carmona, Yolanda, Magri, Giuliana, Cassis, Linda, Segura-Garzón, Daniel, Ciociola, Alessandra, Grasset, Emilie K., Bascones, Sabrina, Comerma, Laura, Pybus, Marc, Lligé, David, Puga, Irene, Gutzeit, Cindy, He, Bing, DuBois, Wendy, Crespo, Marta, Pascual, Julio, Mensa, Anna, Aróstegui, Juan Ignacio, Juan, Manel, Yagüe, Jordi, Serrano, Sergi, Lloreta, Josep, Meffre, Eric, Hahne, Michael, Cunningham-Rundles, Charlotte, Mock, Beverly A., Cerutti, Andrea

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p53 Loss Increases the Osteogenic Differentiation of Bone Marrow Stromal Cells von He, Yunlong, de Castro, Luis F., Shin, Min Hwa, Dubois, Wendy, Yang, Howard H., Jiang, Shunlin, Mishra, Pravin J., Ren, Ling, Gou, Hongfeng, Lal, Ashish, Khanna, Chand, Merlino, Glenn, Lee, Maxwell, Robey, Pamela G., Huang, Jing

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Host CLIC4 expression in the tumor microenvironment is essential for breast cancer metastatic competence von Sanchez, Vanesa C, Yang, Howard H, Craig-Lucas, Alayna, Dubois, Wendy, Carofino, Brandi L, Lack, Justin, Dwyer, Jennifer E, Simpson, R Mark, Cataisson, Christophe, Lee, Max P, Luo, Ji, Hunter, Kent W, Yuspa, Stuart H

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Conventional Co-Housing Modulates Murine Gut Microbiota and Hematopoietic Gene Expression von Chen, Jichun, Zhang, Shuling, Feng, Xingmin, Wu, Zhijie, Dubois, Wendy, Thovarai, Vishal, Ahluwalia, Sonia, Gao, Shouguo, Chen, Jinguo, Peat, Tyler, Sen, Shurjo K., Trinchieri, Giorgio, Young, Neal S., Mock, Beverly A.

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WDR26 and MTF2 are therapeutic targets in multiple myeloma von Sun, Fumou, Cheng, Yan, Riordan, Jesse D., Dupuy, Adam, Dubois, Wendy, Pisano, Michael, Dong, Jing, Mock, Beverly, Zhan, Fenghuang, Hari, Parameswaran, Janz, Siegfried

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Constitutive reductions in mTOR alter cell size, immune cell development, and antibody production von Zhang, Shuling, Readinger, Julie A., DuBois, Wendy, Janka-Junttila, Mirkka, Robinson, Richard, Pruitt, Margaret, Bliskovsky, Val, Wu, Julie Z., Sakakibara, Kaori, Patel, Jyoti, Parent, Carole A., Tessarollo, Lino, Schwartzberg, Pamela L., Mock, Beverly A.

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Cooperative Targets of Combined mTOR/HDAC Inhibition Promote MYC Degradation von Simmons, John K, Michalowski, Aleksandra M, Gamache, Benjamin J, DuBois, Wendy, Patel, Jyoti, Zhang, Ke, Gary, Joy, Zhang, Shuling, Gaikwad, Snehal, Connors, Daniel, Watson, Nicholas, Leon, Elena, Chen, Jin-Qiu, Kuehl, W Michael, Lee, Maxwell P, Zingone, Adriana, Landgren, Ola, Ordentlich, Peter, Huang, Jing, Mock, Beverly A

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AID expression levels determine the extent of cMyc oncogenic translocations and the incidence of B cell tumor development von Takizawa, Makiko, Tolarová, Helena, Li, Zhiyu, Dubois, Wendy, Lim, Susan, Callen, Elsa, Franco, Sonia, Mosaico, Maria, Feigenbaum, Lionel, Alt, Frederick W, Nussenzweig, André, Potter, Michael, Casellas, Rafael

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3D chromatin architecture, BRD4, and Mediator have distinct roles in regulating genome-wide transcriptional bursting and gene network von Trzaskoma, Pawel, Jung, SeolKyoung, Pękowska, Aleksandra, Bohrer, Christopher H, Wang, Xiang, Naz, Faiza, Dell'Orso, Stefania, Dubois, Wendy D, Olivera, Ana, Vartak, Supriya V, Zhao, Yongbing, Nayak, Subhashree, Overmiller, Andrew, Morasso, Maria I, Sartorelli, Vittorio, Larson, Daniel R, Chow, Carson C, Casellas, Rafael, O'Shea, John J

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mTORC1 and mTORC2 differentially regulate homeostasis of neoplastic and non-neoplastic human mast cells von Smrž, Daniel, Kim, Mi-Sun, Zhang, Shuling, Mock, Beverly A., Smržová, Šárka, DuBois, Wendy, Simakova, Olga, Maric, Irina, Wilson, Todd M., Metcalfe, Dean D., Gilfillan, Alasdair M.

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A Genome-wide Map of CTCF Multivalency Redefines the CTCF Code von Nakahashi, Hirotaka, Kwon, Kyong-Rim Kieffer, Resch, Wolfgang, Vian, Laura, Dose, Marei, Stavreva, Diana, Hakim, Ofir, Pruett, Nathanael, Nelson, Steevenson, Yamane, Arito, Qian, Jason, Dubois, Wendy, Welsh, Scott, Phair, Robert D., Pugh, B. Franklin, Lobanenkov, Victor, Hager, Gordon L., Casellas, Rafael

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Loss-of-function RNAi screens in breast cancer cells identify AURKB, PLK1, PIK3R1, MAPK12, PRKD2 , and PTK6 as sensitizing targets of rapamycin activity von Ou, Oliver, Huppi, Konrad, Chakka, Sirisha, Gehlhaus, Kristen, Dubois, Wendy, Patel, Jyoti, Chen, Jinqiu, Mackiewicz, Mark, Jones, Tamara L, Pitt, Jason J, Martin, Scott E, Goldsmith, Paul, Simmons, John K, Mock, Beverly A, Caplen, Natasha J

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cFOS-SOX9 Axis Reprograms Bone Marrow-Derived Mesenchymal Stem Cells into Chondroblastic Osteosarcoma von He, Yunlong, Zhu, Wentao, Shin, Min Hwa, Gary, Joy, Liu, Chengyu, Dubois, Wendy, Hoover, Shelley B., Jiang, Shunlin, Marrogi, Eryney, Mock, Beverly, Simpson, R. Mark, Huang, Jing

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Mouse model of endemic Burkitt translocations reveals the long-range boundaries of Ig-mediated oncogene deregulation von Kovalchuk, Alexander L, Ansarah-Sobrinho, Camilo, Hakim, Ofir, Resch, Wolfgang, Tolarová, Helena, Dubois, Wendy, Yamane, Arito, Takizawa, Makiko, Klein, Isaac, Hager, Gordon L, Morse, Herbert C, Potter, Michael, Nussenzweig, Michel C, Casellas, Rafael

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Mndal, a new interferon-inducible family member, is highly polymorphic, suppresses cell growth, and may modify plasmacytoma susceptibility von Zhang, Ke, Kagan, Daniel, DuBois, Wendy, Robinson, Richard, Bliskovsky, Valery, Vass, William C., Zhang, Shuling, Mock, Beverly A.

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