An Intranasal OMV-Based Vaccine Induces High Mucosal and Systemic Protecting Immunity Against a SARS-CoV-2 Infection von van der Ley, Peter A, Zariri, Afshin, van Riet, Elly, Oosterhoff, Dinja, Kruiswijk, Corine P

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Outer membrane vesicles as platform vaccine technology von van der Pol, Leo, Stork, Michiel, van der Ley, Peter

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Cysteine depletion causes oxidative stress and triggers outer membrane vesicle release by Neisseria meningitidis; implications for vaccine development von van de Waterbeemd, Bas, Zomer, Gijsbert, van den Ijssel, Jan, van Keulen, Lonneke, Eppink, Michel H, van der Ley, Peter, van der Pol, Leo A

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Differential Activation of Human and Mouse Toll-Like Receptor 4 by the Adjuvant Candidate LpxL1 of Neisseria meningitidis von Steeghs, Liana, Keestra, A Marijke, van Mourik, Andries, Uronen-Hansson, Heli, van der Ley, Peter, Callard, Robin, Klein, Nigel, van Putten, Jos P M

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Naturally occurring lipid A mutants in neisseria meningitidis from patients with invasive meningococcal disease are associated with reduced coagulopathy von Fransen, Floris, Heckenberg, Sebastiaan G B, Hamstra, Hendrik Jan, Feller, Moniek, Boog, Claire J P, van Putten, Jos P M, van de Beek, Diederik, van der Ende, Arie, van der Ley, Peter

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Opa⁺ and Opa⁻ Isolates of Neisseria meningitidis and Neisseria gonorrhoeae Induce Sustained Proliferative Responses in Human CD4⁺ T Cells von Youssef, Abdel-Rahman, van der Flier, Michiel, Estevão, Silvia, Hartwig, Nico G, van der Ley, Peter, Virji, Mumtaz

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Coincorporation of LpxL1 and PagL Mutant Lipopolysaccharides into Liposomes with Neisseria meningitidis Opacity Protein: Influence on Endotoxic and Adjuvant Activity von Arenas, Jesús, van Dijken, Harry, Kuipers, Betsy, Hamstra, Hendrik Jan, Tommassen, Jan, van der Ley, Peter

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Identification of a Novel Lipopolysaccharide Core Biosynthesis Gene Cluster in Bordetella pertussis, and Influence of Core Structure and Lipid A Glucosamine Substitution on Endotox... von Geurtsen, Jeroen, Dzieciatkowska, Monika, Steeghs, Liana, Hamstra, Hendrik-Jan, Boleij, Johanna, Broen, Kelly, Akkerman, Grietsje, el Hassan, Hassan, Li, Jianjun, Richards, James C, Tommassen, Jan, van der Ley, Peter

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Structure of Neisseria meningitidis Lipid A Determines Outcome in Experimental Meningococcal Disease von Fransen, Floris, Hamstra, Hendrik Jan, Boog, Claire J, van Putten, Jos P, van den Dobbelsteen, Germie P.J.M, van der Ley, Peter

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Antigen sparing with adjuvanted inactivated polio vaccine based on Sabin strains von Westdijk, Janny, Koedam, Patrick, Barro, Mario, Steil, Benjamin P, Collin, Nicolas, Vedvick, Thomas S, Bakker, Wilfried A.M, van der Ley, Peter, Kersten, Gideon

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Surface display of a borrelial lipoprotein on meningococcal outer membrane vesicles von Salverda, Merijn L.M, Meinderts, Sanne M, Hamstra, Hendrik-Jan, Wagemakers, Alex, Hovius, Joppe W.R, van der Ark, Arno, Stork, Michiel, van der Ley, Peter

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Next-generation outer membrane vesicle vaccines against Neisseria meningitidis based on nontoxic LPS mutants von van der Ley, Peter, van den Dobbelsteen, Germie

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Bordetella pertussis naturally occurring isolates with altered lipooligosaccharide structure fail to fully mature human dendritic cells von Brummelman, Jolanda, Veerman, Rosanne E, Hamstra, Hendrik Jan, Deuss, Anna J M, Schuijt, Tim J, Sloots, Arjen, Kuipers, Betsy, van Els, Cécile A C M, van der Ley, Peter, Mooi, Frits R, Han, Wanda G H, Pinelli, Elena

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Rational Vaccine Design in Times of Emerging Diseases: The Critical Choices of Immunological Correlates of Protection, Vaccine Antigen and Immunomodulation von Schijns, Virgil, Majhen, Dragomira, van der Ley, Peter, Thakur, Aneesh, Summerfield, Artur, Berisio, Rita, Nativi, Cristina, Fernández-Tejada, Alberto, Alvarez-Dominguez, Carmen, Gizurarson, Sveinbjörn, Zamyatina, Alla, Molinaro, Antonio, Rosano, Camillo, Jakopin, Žiga, Gursel, Ihsan, McClean, Siobhán

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Lipoarabinomannan mannose caps do not affect mycobacterial virulence or the induction of protective immunity in experimental animal models of infection and have minimal impact on i... von Afonso‐Barroso, António, Clark, Simon O., Williams, Ann, Rosa, Gustavo T., Nóbrega, Cláudia, Silva‐Gomes, Sandro, Vale‐Costa, Sílvia, Ummels, Roy, Stoker, Neil, Movahedzadeh, Farahnaz, der Ley, Peter, Sloots, Arjen, Cot, Marlène, Appelmelk, Ben J., Puzo, Germain, Nigou, Jérôme, Geurtsen, Jeroen, Appelberg, Rui

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Shortening the Lipid A Acyl Chains of Bordetella pertussis Enables Depletion of Lipopolysaccharide Endotoxic Activity von Arenas, Jesús, Pupo, Elder, Phielix, Coen, David, Dionne, Zariri, Afshin, Zamyatina, Alla, Tommassen, Jan, van der Ley, Peter

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Agonists of Toll-Like Receptors 3, 4, 7, and 9 Are Candidates for Use as Adjuvants in an Outer Membrane Vaccine against Neisseria meningitidis Serogroup B von Fransen, Floris, Boog, Claire J, van Putten, Jos P, van der Ley, Peter

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Outer membrane vesicle-based intranasal vaccines von Van der Ley, Peter, Schijns, Virgil EJC

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Differential effect of TLR2 and TLR4 on the immune response after immunization with a vaccine against Neisseria meningitidis or Bordetella pertussis von Fransen, Floris, Stenger, Rachel M, Poelen, Martien C M, van Dijken, Harry H, Kuipers, Betsy, Boog, Claire J P, van Putten, Jos P M, van Els, Cécile A C M, van der Ley, Peter

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A Lipopolysaccharide-Deficient Mutant of Neisseria meningitidis Elicits Attenuated Cytokine Release by Human Macrophages and Signals via Toll-like Receptor (TLR) 2 but Not via TLR4... von Pridmore, Alison C., Wyllie, David H., Abdillahi, Fatumo, Steeghs, Liana, van der Ley, Peter, Dower, Steven K., Read, Robert C.

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